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5. Effects of the KCNQ channel opener ezogabine on functional connectivity of the ventral striatum and clinical symptoms in patients with major depressive disorder. Tan A; Costi S; Morris LS; Van Dam NT; Kautz M; Whitton AE; Friedman AK; Collins KA; Ahle G; Chadha N; Do B; Pizzagalli DA; Iosifescu DV; Nestler EJ; Han MH; Murrough JW Mol Psychiatry; 2020 Jun; 25(6):1323-1333. PubMed ID: 30385872 [TBL] [Abstract][Full Text] [Related]
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7. Impact of the KCNQ2/3 Channel Opener Ezogabine on Reward Circuit Activity and Clinical Symptoms in Depression: Results From a Randomized Controlled Trial. Costi S; Morris LS; Kirkwood KA; Hoch M; Corniquel M; Vo-Le B; Iqbal T; Chadha N; Pizzagalli DA; Whitton A; Bevilacqua L; Jha MK; Ursu S; Swann AC; Collins KA; Salas R; Bagiella E; Parides MK; Stern ER; Iosifescu DV; Han MH; Mathew SJ; Murrough JW Am J Psychiatry; 2021 May; 178(5):437-446. PubMed ID: 33653118 [TBL] [Abstract][Full Text] [Related]
8. Activation of KCNQ Channels Suppresses Spontaneous Activity in Dorsal Root Ganglion Neurons and Reduces Chronic Pain after Spinal Cord Injury. Wu Z; Li L; Xie F; Du J; Zuo Y; Frost JA; Carlton SM; Walters ET; Yang Q J Neurotrauma; 2017 Mar; 34(6):1260-1270. PubMed ID: 28073317 [TBL] [Abstract][Full Text] [Related]
9. Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience. Friedman AK; Walsh JJ; Juarez B; Ku SM; Chaudhury D; Wang J; Li X; Dietz DM; Pan N; Vialou VF; Neve RL; Yue Z; Han MH Science; 2014 Apr; 344(6181):313-9. PubMed ID: 24744379 [TBL] [Abstract][Full Text] [Related]
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11. The neuronal KCNQ channel opener retigabine inhibits locomotor activity and reduces forebrain excitatory responses to the psychostimulants cocaine, methylphenidate and phencyclidine. Hansen HH; Andreasen JT; Weikop P; Mirza N; Scheel-Krüger J; Mikkelsen JD Eur J Pharmacol; 2007 Sep; 570(1-3):77-88. PubMed ID: 17628530 [TBL] [Abstract][Full Text] [Related]
12. The KCNQ channel opener retigabine inhibits the activity of mesencephalic dopaminergic systems of the rat. Hansen HH; Ebbesen C; Mathiesen C; Weikop P; Rønn LC; Waroux O; Scuvée-Moreau J; Seutin V; Mikkelsen JD J Pharmacol Exp Ther; 2006 Sep; 318(3):1006-19. PubMed ID: 16775195 [TBL] [Abstract][Full Text] [Related]
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14. KCNQ2/3 openers show differential selectivity and site of action across multiple KCNQ channels. Zhang D; Thimmapaya R; Zhang XF; Anderson DJ; Baranowski JL; Scanio M; Perez-Medrano A; Peddi S; Wang Z; Patel JR; DeGoey DA; Gopalakrishnan M; Honore P; Yao BB; Surowy CS J Neurosci Methods; 2011 Aug; 200(1):54-62. PubMed ID: 21723881 [TBL] [Abstract][Full Text] [Related]
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17. The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation. Dost R; Rostock A; Rundfeldt C Naunyn Schmiedebergs Arch Pharmacol; 2004 Apr; 369(4):382-90. PubMed ID: 15007538 [TBL] [Abstract][Full Text] [Related]
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20. The mechanism of action of retigabine (ezogabine), a first-in-class K+ channel opener for the treatment of epilepsy. Gunthorpe MJ; Large CH; Sankar R Epilepsia; 2012 Mar; 53(3):412-24. PubMed ID: 22220513 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]