305 related articles for article (PubMed ID: 27219534)
1. The microglial ATP-gated ion channel P2X7 as a CNS drug target.
Bhattacharya A; Biber K
Glia; 2016 Oct; 64(10):1772-87. PubMed ID: 27219534
[TBL] [Abstract][Full Text] [Related]
2. The evolution of P2X7 antagonists with a focus on CNS indications.
Rech JC; Bhattacharya A; Letavic MA; Savall BM
Bioorg Med Chem Lett; 2016 Aug; 26(16):3838-45. PubMed ID: 27426304
[TBL] [Abstract][Full Text] [Related]
3. A central role for P2X7 receptors in human microglia.
Janks L; Sharma CVR; Egan TM
J Neuroinflammation; 2018 Nov; 15(1):325. PubMed ID: 30463629
[TBL] [Abstract][Full Text] [Related]
4. Neuropsychopharmacology of JNJ-55308942: evaluation of a clinical candidate targeting P2X7 ion channels in animal models of neuroinflammation and anhedonia.
Bhattacharya A; Lord B; Grigoleit JS; He Y; Fraser I; Campbell SN; Taylor N; Aluisio L; O'Connor JC; Papp M; Chrovian C; Carruthers N; Lovenberg TW; Letavic MA
Neuropsychopharmacology; 2018 Dec; 43(13):2586-2596. PubMed ID: 30026598
[TBL] [Abstract][Full Text] [Related]
5. P2X7 Receptors Amplify CNS Damage in Neurodegenerative Diseases.
Illes P
Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32825423
[TBL] [Abstract][Full Text] [Related]
6. The azetidine derivative, KHG26792 protects against ATP-induced activation of NFAT and MAPK pathways through P2X7 receptor in microglia.
Kim EA; Cho CH; Kim J; Hahn HG; Choi SY; Yang SJ; Cho SW
Neurotoxicology; 2015 Dec; 51():198-206. PubMed ID: 26522449
[TBL] [Abstract][Full Text] [Related]
7. Ion channels on microglia: therapeutic targets for neuroprotection.
Skaper SD
CNS Neurol Disord Drug Targets; 2011 Feb; 10(1):44-56. PubMed ID: 21143139
[TBL] [Abstract][Full Text] [Related]
8. Recent Advances in CNS P2X7 Physiology and Pharmacology: Focus on Neuropsychiatric Disorders.
Bhattacharya A
Front Pharmacol; 2018; 9():30. PubMed ID: 29449810
[TBL] [Abstract][Full Text] [Related]
9. Leveraging the ATP-P2X7 receptor signalling axis to alleviate traumatic CNS damage and related complications.
Yin Y; Wei L; Caseley EA; Lopez-Charcas O; Wei Y; Li D; Muench SP; Roger S; Wang L; Jiang LH
Med Res Rev; 2023 Sep; 43(5):1346-1373. PubMed ID: 36924449
[TBL] [Abstract][Full Text] [Related]
10. P2X7 antagonists as potential therapeutic agents for the treatment of CNS disorders.
Chrovian CC; Rech JC; Bhattacharya A; Letavic MA
Prog Med Chem; 2014; 53():65-100. PubMed ID: 24418608
[TBL] [Abstract][Full Text] [Related]
11. Emerging role of the P2X7-NLRP3-IL1β pathway in mood disorders.
Bhattacharya A; Jones DNC
Psychoneuroendocrinology; 2018 Dec; 98():95-100. PubMed ID: 30121550
[TBL] [Abstract][Full Text] [Related]
12. A novel radioligand for the ATP-gated ion channel P2X7: [3H] JNJ-54232334.
Lord B; Ameriks MK; Wang Q; Fourgeaud L; Vliegen M; Verluyten W; Haspeslagh P; Carruthers NI; Lovenberg TW; Bonaventure P; Letavic MA; Bhattacharya A
Eur J Pharmacol; 2015 Oct; 765():551-9. PubMed ID: 26386289
[TBL] [Abstract][Full Text] [Related]
13. ATP-activated P2X7 receptor in the pathophysiology of mood disorders and as an emerging target for the development of novel antidepressant therapeutics.
Wei L; Syed Mortadza SA; Yan J; Zhang L; Wang L; Yin Y; Li C; Chalon S; Emond P; Belzung C; Li D; Lu C; Roger S; Jiang LH
Neurosci Biobehav Rev; 2018 Apr; 87():192-205. PubMed ID: 29453990
[TBL] [Abstract][Full Text] [Related]
14. Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432.
Lord B; Aluisio L; Shoblock JR; Neff RA; Varlinskaya EI; Ceusters M; Lovenberg TW; Carruthers N; Bonaventure P; Letavic MA; Deak T; Drinkenburg W; Bhattacharya A
J Pharmacol Exp Ther; 2014 Dec; 351(3):628-41. PubMed ID: 25271258
[TBL] [Abstract][Full Text] [Related]
15. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody.
Kaczmarek-Hajek K; Zhang J; Kopp R; Grosche A; Rissiek B; Saul A; Bruzzone S; Engel T; Jooss T; Krautloher A; Schuster S; Magnus T; Stadelmann C; Sirko S; Koch-Nolte F; Eulenburg V; Nicke A
Elife; 2018 Aug; 7():. PubMed ID: 30074479
[TBL] [Abstract][Full Text] [Related]
16. Extracellular ATP enhances radiation-induced brain injury through microglial activation and paracrine signaling via P2X7 receptor.
Xu P; Xu Y; Hu B; Wang J; Pan R; Murugan M; Wu LJ; Tang Y
Brain Behav Immun; 2015 Nov; 50():87-100. PubMed ID: 26122280
[TBL] [Abstract][Full Text] [Related]
17. P2X7-dependent, but differentially regulated release of IL-6, CCL2, and TNF-α in cultured mouse microglia.
Shieh CH; Heinrich A; Serchov T; van Calker D; Biber K
Glia; 2014 Apr; 62(4):592-607. PubMed ID: 24470356
[TBL] [Abstract][Full Text] [Related]
18. Antagonism of the brain P2X7 ion channel attenuates repeated social defeat induced microglia reactivity, monocyte recruitment and anxiety-like behavior in male mice.
Biltz RG; Swanson SP; Draime N; Davis AC; Yin W; Goodman EJ; Gallagher NR; Bhattacharya A; Sheridan JF; Godbout JP
Brain Behav Immun; 2024 Jan; 115():356-373. PubMed ID: 37914101
[TBL] [Abstract][Full Text] [Related]
19. New Inhibitory Effects of Cilnidipine on Microglial P2X7 Receptors and IL-1β Release: An Involvement in its Alleviating Effect on Neuropathic Pain.
Yamashita T; Kamikaseda S; Tanaka A; Tozaki-Saitoh H; Caaveiro JMM; Inoue K; Tsuda M
Cells; 2021 Feb; 10(2):. PubMed ID: 33670748
[TBL] [Abstract][Full Text] [Related]
20. Interactions of pannexin 1 with NMDA and P2X7 receptors in central nervous system pathologies: Possible role on chronic pain.
Bravo D; Maturana CJ; Pelissier T; Hernández A; Constandil L
Pharmacol Res; 2015 Nov; 101():86-93. PubMed ID: 26211949
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]