216 related articles for article (PubMed ID: 27220848)
1. Histone H3.3 promotes IgV gene diversification by enhancing formation of AID-accessible single-stranded DNA.
Romanello M; Schiavone D; Frey A; Sale JE
EMBO J; 2016 Jul; 35(13):1452-64. PubMed ID: 27220848
[TBL] [Abstract][Full Text] [Related]
2. SRSF1-3 contributes to diversification of the immunoglobulin variable region gene by promoting accumulation of AID in the nucleus.
Kawaguchi Y; Nariki H; Kawamoto N; Kanehiro Y; Miyazaki S; Suzuki M; Magari M; Tokumitsu H; Kanayama N
Biochem Biophys Res Commun; 2017 Apr; 485(2):261-266. PubMed ID: 28235482
[TBL] [Abstract][Full Text] [Related]
3. Pold4, the fourth subunit of replicative polymerase δ, suppresses gene conversion in the immunoglobulin-variable gene in avian DT40 cells.
Kojima K; Ooka M; Abe T; Hirota K
DNA Repair (Amst); 2021 Apr; 100():103056. PubMed ID: 33588156
[TBL] [Abstract][Full Text] [Related]
4. Negative supercoiling creates single-stranded patches of DNA that are substrates for AID-mediated mutagenesis.
Parsa JY; Ramachandran S; Zaheen A; Nepal RM; Kapelnikov A; Belcheva A; Berru M; Ronai D; Martin A
PLoS Genet; 2012 Feb; 8(2):e1002518. PubMed ID: 22346767
[TBL] [Abstract][Full Text] [Related]
5. SRSF1-3, a splicing and somatic hypermutation regulator, controls transcription of IgV genes via chromatin regulators SATB2, UBN1 and histone variant H3.3.
Singh AK; Tamrakar A; Jaiswal A; Kanayama N; Kodgire P
Mol Immunol; 2020 Mar; 119():69-82. PubMed ID: 31986311
[TBL] [Abstract][Full Text] [Related]
6. Activation-induced cytidine deaminase (AID)-dependent somatic hypermutation requires a splice isoform of the serine/arginine-rich (SR) protein SRSF1.
Kanehiro Y; Todo K; Negishi M; Fukuoka J; Gan W; Hikasa T; Kaga Y; Takemoto M; Magari M; Li X; Manley JL; Ohmori H; Kanayama N
Proc Natl Acad Sci U S A; 2012 Jan; 109(4):1216-21. PubMed ID: 22232677
[TBL] [Abstract][Full Text] [Related]
7. Immunoglobulin gene conversion in chicken DT40 cells largely proceeds through an abasic site intermediate generated by excision of the uracil produced by AID-mediated deoxycytidine deamination.
Di Noia JM; Neuberger MS
Eur J Immunol; 2004 Feb; 34(2):504-8. PubMed ID: 14768055
[TBL] [Abstract][Full Text] [Related]
8. Single-stranded DNA structure and positional context of the target cytidine determine the enzymatic efficiency of AID.
Larijani M; Martin A
Mol Cell Biol; 2007 Dec; 27(23):8038-48. PubMed ID: 17893327
[TBL] [Abstract][Full Text] [Related]
9. Enhancement of hypermutation frequency in the chicken B cell line DT40 for efficient diversification of the antibody repertoire.
Magari M; Kanehiro Y; Todo K; Ikeda M; Kanayama N; Ohmori H
Biochem Biophys Res Commun; 2010 May; 396(2):353-8. PubMed ID: 20416279
[TBL] [Abstract][Full Text] [Related]
10. GANP regulates the choice of DNA repair pathway by DNA-PKcs interaction in AID-dependent IgV region diversification.
Eid MM; Maeda K; Almofty SA; Singh SK; Shimoda M; Sakaguchi N
J Immunol; 2014 Jun; 192(12):5529-39. PubMed ID: 24808370
[TBL] [Abstract][Full Text] [Related]
11. GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy.
Singh SK; Maeda K; Eid MM; Almofty SA; Ono M; Pham P; Goodman MF; Sakaguchi N
Nat Commun; 2013; 4():1830. PubMed ID: 23652018
[TBL] [Abstract][Full Text] [Related]
12. Transcription-targeted DNA deamination by the AID antibody diversification enzyme.
Chaudhuri J; Tian M; Khuong C; Chua K; Pinaud E; Alt FW
Nature; 2003 Apr; 422(6933):726-30. PubMed ID: 12692563
[TBL] [Abstract][Full Text] [Related]
13. Activation-induced cytidine deaminase can target multiple topologies of double-stranded DNA in a transcription-independent manner.
Branton SA; Ghorbani A; Bolt BN; Fifield H; Berghuis LM; Larijani M
FASEB J; 2020 Jul; 34(7):9245-9268. PubMed ID: 32437054
[TBL] [Abstract][Full Text] [Related]
14. Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA.
Brar SS; Sacho EJ; Tessmer I; Croteau DL; Erie DA; Diaz M
DNA Repair (Amst); 2008 Jan; 7(1):77-87. PubMed ID: 17889624
[TBL] [Abstract][Full Text] [Related]
15. Molecular mechanism of immunoglobulin V-region diversification regulated by transcription and RNA metabolism in antigen-driven B cells.
Sakaguchi N; Maeda K; Kuwahara K
Scand J Immunol; 2011 Jun; 73(6):520-6. PubMed ID: 21388430
[TBL] [Abstract][Full Text] [Related]
16. Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase.
Bransteitter R; Pham P; Scharff MD; Goodman MF
Proc Natl Acad Sci U S A; 2003 Apr; 100(7):4102-7. PubMed ID: 12651944
[TBL] [Abstract][Full Text] [Related]
17. The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription.
Shen HM; Poirier MG; Allen MJ; North J; Lal R; Widom J; Storb U
J Exp Med; 2009 May; 206(5):1057-71. PubMed ID: 19380635
[TBL] [Abstract][Full Text] [Related]
18. Integrity of immunoglobulin variable regions is supported by GANP during AID-induced somatic hypermutation in germinal center B cells.
Eid MMA; Shimoda M; Singh SK; Almofty SA; Pham P; Goodman MF; Maeda K; Sakaguchi N
Int Immunol; 2017 May; 29(5):211-220. PubMed ID: 28541550
[TBL] [Abstract][Full Text] [Related]
19. Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID.
Wang M; Rada C; Neuberger MS
J Exp Med; 2010 Jan; 207(1):141-53. PubMed ID: 20048284
[TBL] [Abstract][Full Text] [Related]
20. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.
Di Noia J; Neuberger MS
Nature; 2002 Sep; 419(6902):43-8. PubMed ID: 12214226
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]