BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

292 related articles for article (PubMed ID: 27221467)

  • 1. MicroRNA-146a suppresses ROCK1 allowing hyperphosphorylation of tau in Alzheimer's disease.
    Wang G; Huang Y; Wang LL; Zhang YF; Xu J; Zhou Y; Lourenco GF; Zhang B; Wang Y; Ren RJ; Halliday GM; Chen SD
    Sci Rep; 2016 May; 6():26697. PubMed ID: 27221467
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease.
    Banzhaf-Strathmann J; Benito E; May S; Arzberger T; Tahirovic S; Kretzschmar H; Fischer A; Edbauer D
    EMBO J; 2014 Aug; 33(15):1667-80. PubMed ID: 25001178
    [TBL] [Abstract][Full Text] [Related]  

  • 3. miR-200c suppression increases tau hyperphosphorylation by targeting 14-3-3γ in early stage of 5xFAD mouse model of Alzheimer's disease.
    Park H; Lee YB; Chang KA
    Int J Biol Sci; 2022; 18(5):2220-2234. PubMed ID: 35342350
    [No Abstract]   [Full Text] [Related]  

  • 4. miR-106b inhibits tau phosphorylation at Tyr18 by targeting Fyn in a model of Alzheimer's disease.
    Liu W; Zhao J; Lu G
    Biochem Biophys Res Commun; 2016 Sep; 478(2):852-7. PubMed ID: 27520374
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MicroRNA-922 promotes tau phosphorylation by downregulating ubiquitin carboxy-terminal hydrolase L1 (UCHL1) expression in the pathogenesis of Alzheimer's disease.
    Zhao ZB; Wu L; Xiong R; Wang LL; Zhang B; Wang C; Li H; Liang L; Chen SD
    Neuroscience; 2014 Sep; 275():232-7. PubMed ID: 24950120
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-β levels in brain.
    Henderson BW; Gentry EG; Rush T; Troncoso JC; Thambisetty M; Montine TJ; Herskowitz JH
    J Neurochem; 2016 Aug; 138(4):525-31. PubMed ID: 27246255
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Knockdown of long non-coding RNA TUG1 depresses apoptosis of hippocampal neurons in Alzheimer's disease by elevating microRNA-15a and repressing ROCK1 expression.
    Li X; Wang SW; Li XL; Yu FY; Cong HM
    Inflamm Res; 2020 Sep; 69(9):897-910. PubMed ID: 32577774
    [TBL] [Abstract][Full Text] [Related]  

  • 8. O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease.
    Liu F; Iqbal K; Grundke-Iqbal I; Hart GW; Gong CX
    Proc Natl Acad Sci U S A; 2004 Jul; 101(29):10804-9. PubMed ID: 15249677
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The novel calpain inhibitor A-705253 prevents stress-induced tau hyperphosphorylation in vitro and in vivo.
    Nikkel AL; Martino B; Markosyan S; Brederson JD; Medeiros R; Moeller A; Bitner RS
    Neuropharmacology; 2012 Sep; 63(4):606-12. PubMed ID: 22613839
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease.
    Gong CX; Iqbal K
    Curr Med Chem; 2008; 15(23):2321-8. PubMed ID: 18855662
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: implications for Alzheimer's disease.
    Planel E; Miyasaka T; Launey T; Chui DH; Tanemura K; Sato S; Murayama O; Ishiguro K; Tatebayashi Y; Takashima A
    J Neurosci; 2004 Mar; 24(10):2401-11. PubMed ID: 15014115
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers.
    De Felice FG; Wu D; Lambert MP; Fernandez SJ; Velasco PT; Lacor PN; Bigio EH; Jerecic J; Acton PJ; Shughrue PJ; Chen-Dodson E; Kinney GG; Klein WL
    Neurobiol Aging; 2008 Sep; 29(9):1334-47. PubMed ID: 17403556
    [TBL] [Abstract][Full Text] [Related]  

  • 13. UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation.
    Subramanian M; Hyeon SJ; Das T; Suh YS; Kim YK; Lee JS; Song EJ; Ryu H; Yu K
    Nat Commun; 2021 Jun; 12(1):3291. PubMed ID: 34078905
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reduced miR-512 and the Elevated Expression of Its Targets cFLIP and MCL1 Localize to Neurons With Hyperphosphorylated Tau Protein in Alzheimer Disease.
    Mezache L; Mikhail M; Garofalo M; Nuovo GJ
    Appl Immunohistochem Mol Morphol; 2015 Oct; 23(9):615-23. PubMed ID: 26258756
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation of tau antagonizes apoptosis by stabilizing beta-catenin, a mechanism involved in Alzheimer's neurodegeneration.
    Li HL; Wang HH; Liu SJ; Deng YQ; Zhang YJ; Tian Q; Wang XC; Chen XQ; Yang Y; Zhang JY; Wang Q; Xu H; Liao FF; Wang JZ
    Proc Natl Acad Sci U S A; 2007 Feb; 104(9):3591-6. PubMed ID: 17360687
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alpha1-antichymotrypsin, an inflammatory protein overexpressed in Alzheimer's disease brain, induces tau phosphorylation in neurons.
    Padmanabhan J; Levy M; Dickson DW; Potter H
    Brain; 2006 Nov; 129(Pt 11):3020-34. PubMed ID: 16987932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tau pathology in Alzheimer disease and other tauopathies.
    Iqbal K; Alonso Adel C; Chen S; Chohan MO; El-Akkad E; Gong CX; Khatoon S; Li B; Liu F; Rahman A; Tanimukai H; Grundke-Iqbal I
    Biochim Biophys Acta; 2005 Jan; 1739(2-3):198-210. PubMed ID: 15615638
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MicroRNA-146a regulates the expression of the Aβ1-42 protein in Alzheimer's disease.
    Huang P; Xu M; He YX
    Eur Rev Med Pharmacol Sci; 2021 Feb; 25(4):2003-2012. PubMed ID: 33660812
    [TBL] [Abstract][Full Text] [Related]  

  • 19. JNK plays a key role in tau hyperphosphorylation in Alzheimer's disease models.
    Ploia C; Antoniou X; Sclip A; Grande V; Cardinetti D; Colombo A; Canu N; Benussi L; Ghidoni R; Forloni G; Borsello T
    J Alzheimers Dis; 2011; 26(2):315-29. PubMed ID: 21628793
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer's Disease.
    Liu Z; Li T; Li P; Wei N; Zhao Z; Liang H; Ji X; Chen W; Xue M; Wei J
    Oxid Med Cell Longev; 2015; 2015():352723. PubMed ID: 26171115
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.