These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

293 related articles for article (PubMed ID: 27223062)

  • 21. Functional evaluation of the role of inhibitor of apoptosis proteins in chronic lymphocytic leukemia.
    Schliep S; Decker T; Schneller F; Wagner H; Häcker G
    Exp Hematol; 2004 Jun; 32(6):556-62. PubMed ID: 15183896
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Targeting XIAP for Promoting Cancer Cell Death-The Story of ARTS and SMAC.
    Abbas R; Larisch S
    Cells; 2020 Mar; 9(3):. PubMed ID: 32182843
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases.
    Samuel T; Welsh K; Lober T; Togo SH; Zapata JM; Reed JC
    J Biol Chem; 2006 Jan; 281(2):1080-90. PubMed ID: 16282325
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Targeting inhibitor of apoptosis proteins by Smac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia.
    Opel D; Schnaiter A; Dodier D; Jovanovic M; Gerhardinger A; Idler I; Mertens D; Bullinger L; Stilgenbauer S; Fulda S
    Int J Cancer; 2015 Dec; 137(12):2959-70. PubMed ID: 26096065
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine-conjugated Smac peptide.
    Yang L; Mashima T; Sato S; Mochizuki M; Sakamoto H; Yamori T; Oh-Hara T; Tsuruo T
    Cancer Res; 2003 Feb; 63(4):831-7. PubMed ID: 12591734
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Disturbed XIAP and XAF1 expression balance is an independent prognostic factor in gastric adenocarcinomas.
    Shibata T; Noguchi T; Takeno S; Gabbert HE; Ramp U; Kawahara K
    Ann Surg Oncol; 2008 Dec; 15(12):3579-87. PubMed ID: 18807090
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2.
    Darding M; Feltham R; Tenev T; Bianchi K; Benetatos C; Silke J; Meier P
    Cell Death Differ; 2011 Aug; 18(8):1376-86. PubMed ID: 21331077
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Design and characterization of bivalent Smac-based peptides as antagonists of XIAP and development and validation of a fluorescence polarization assay for XIAP containing both BIR2 and BIR3 domains.
    Nikolovska-Coleska Z; Meagher JL; Jiang S; Kawamoto SA; Gao W; Yi H; Qin D; Roller PP; Stuckey JA; Wang S
    Anal Biochem; 2008 Mar; 374(1):87-98. PubMed ID: 18023397
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Tipping the Noxa/Mcl-1 balance overcomes ABT-737 resistance in chronic lymphocytic leukemia.
    Tromp JM; Geest CR; Breij EC; Elias JA; van Laar J; Luijks DM; Kater AP; Beaumont T; van Oers MH; Eldering E
    Clin Cancer Res; 2012 Jan; 18(2):487-98. PubMed ID: 22128299
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent Smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP.
    Sun H; Nikolovska-Coleska Z; Lu J; Meagher JL; Yang CY; Qiu S; Tomita Y; Ueda Y; Jiang S; Krajewski K; Roller PP; Stuckey JA; Wang S
    J Am Chem Soc; 2007 Dec; 129(49):15279-94. PubMed ID: 17999504
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Peptides mimicking the unique ARTS-XIAP binding site promote apoptotic cell death in cultured cancer cells.
    Edison N; Reingewertz TH; Gottfried Y; Lev T; Zuri D; Maniv I; Carp MJ; Shalev G; Friedler A; Larisch S
    Clin Cancer Res; 2012 May; 18(9):2569-78. PubMed ID: 22392914
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis.
    Srinivasula SM; Hegde R; Saleh A; Datta P; Shiozaki E; Chai J; Lee RA; Robbins PD; Fernandes-Alnemri T; Shi Y; Alnemri ES
    Nature; 2001 Mar; 410(6824):112-6. PubMed ID: 11242052
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-κB activation, and is active in patient-derived xenograft models.
    Benetatos CA; Mitsuuchi Y; Burns JM; Neiman EM; Condon SM; Yu G; Seipel ME; Kapoor GS; Laporte MG; Rippin SR; Deng Y; Hendi MS; Tirunahari PK; Lee YH; Haimowitz T; Alexander MD; Graham MA; Weng D; Shi Y; McKinlay MA; Chunduru SK
    Mol Cancer Ther; 2014 Apr; 13(4):867-79. PubMed ID: 24563541
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Phosphorylation of Smac by Akt promotes the caspase-3 activation during etoposide-induced apoptosis in HeLa cells.
    Jeong CH; Chun KS; Kundu J; Park B
    Mol Carcinog; 2015 Feb; 54(2):83-92. PubMed ID: 24038446
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Rapid induction of IAP family proteins and Smac/DIABLO expression after proapoptotic stimulation with doxorubicin in RPMI 8226 multiple myeloma cells.
    Abe S; Hasegawa M; Yamamoto K; Kurata M; Nakagawa Y; Suzuki K; Takizawa T; Kitagawa M
    Exp Mol Pathol; 2007 Dec; 83(3):405-12. PubMed ID: 17521628
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Modulation of Respiration and Mitochondrial Dynamics by SMAC-Mimetics for Combination Therapy in Chemoresistant Cancer.
    Hagenbuchner J; Oberacher H; Arnhard K; Kiechl-Kohlendorfer U; Ausserlechner MJ
    Theranostics; 2019; 9(17):4909-4922. PubMed ID: 31410190
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Immunoexpression of inhibitors of apoptosis proteins and their antagonist SMAC/DIABLO in colorectal carcinoma: correlation with apoptotic index, cellular proliferation and prognosis.
    De Oliveira Lima F; De Oliveira Costa H; Barrezueta LF; Fujiyama Oshima CT; Silva JA; Gomes TS; Pinheiro N; Neto RA; Franco M
    Oncol Rep; 2009 Aug; 22(2):295-303. PubMed ID: 19578769
    [TBL] [Abstract][Full Text] [Related]  

  • 38. ARTS binds to a distinct domain in XIAP-BIR3 and promotes apoptosis by a mechanism that is different from other IAP-antagonists.
    Bornstein B; Gottfried Y; Edison N; Shekhtman A; Lev T; Glaser F; Larisch S
    Apoptosis; 2011 Sep; 16(9):869-81. PubMed ID: 21695558
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Integrity of XIAP is essential for effective activity recovery of apoptosome and its downstream caspases by Smac/Diablo.
    Attaran-Bandarabadi F; Abhari BA; Neishabouri SH; Davoodi J
    Int J Biol Macromol; 2017 Aug; 101():283-289. PubMed ID: 28322955
    [TBL] [Abstract][Full Text] [Related]  

  • 40. PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
    Saita S; Nolte H; Fiedler KU; Kashkar H; Venne AS; Zahedi RP; Krüger M; Langer T
    Nat Cell Biol; 2017 Apr; 19(4):318-328. PubMed ID: 28288130
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.