These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 27224922)

  • 1. Inhibition of neddylation regulates dendritic cell functions via Deptor accumulation driven mTOR inactivation.
    Cheng M; Hu S; Wang Z; Pei Y; Fan R; Liu X; Wang L; Zhou J; Zheng S; Zhang T; Lin Y; Zhang M; Tao R; Zhong J
    Oncotarget; 2016 Jun; 7(24):35643-35654. PubMed ID: 27224922
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis.
    Serrano-Maciá M; Simón J; González-Rellan MJ; Azkargorta M; Goikoetxea-Usandizaga N; Lopitz-Otsoa F; De Urturi DS; Rodríguez-Agudo R; Lachiondo-Ortega S; Mercado-Gomez M; Gutiérrez de Juan V; Bizkarguenaga M; Fernández-Ramos D; Buque X; Baselli GA; Valenti LVC; Iruzubieta P; Crespo J; Villa E; Banales JM; Avila MA; Marin JJG; Aspichueta P; Sutherland J; Barrio R; Mayor U; Elortza F; Xirodimas DP; Nogueiras R; Delgado TC; Martínez-Chantar ML
    Mol Metab; 2021 Nov; 53():101275. PubMed ID: 34153521
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neddylation plays an important role in the regulation of murine and human dendritic cell function.
    Mathewson N; Toubai T; Kapeles S; Sun Y; Oravecz-Wilson K; Tamaki H; Wang Y; Hou G; Sun Y; Reddy P
    Blood; 2013 Sep; 122(12):2062-73. PubMed ID: 23863900
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neddylation pathway regulates the proliferation and survival of macrophages.
    Li L; Liu B; Dong T; Lee HW; Yu J; Zheng Y; Gao H; Zhang Y; Chu Y; Liu G; Niu W; Zheng S; Jeong LS; Jia L
    Biochem Biophys Res Commun; 2013 Mar; 432(3):494-8. PubMed ID: 23416079
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stabilization of HIF through inhibition of Cullin-2 neddylation is protective in mucosal inflammatory responses.
    Curtis VF; Ehrentraut SF; Campbell EL; Glover LE; Bayless A; Kelly CJ; Kominsky DJ; Colgan SP
    FASEB J; 2015 Jan; 29(1):208-15. PubMed ID: 25326537
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Suppression of glioblastoma by targeting the overactivated protein neddylation pathway.
    Hua W; Li C; Yang Z; Li L; Jiang Y; Yu G; Zhu W; Liu Z; Duan S; Chu Y; Yang M; Zhang Y; Mao Y; Jia L
    Neuro Oncol; 2015 Oct; 17(10):1333-43. PubMed ID: 25904638
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deregulated neddylation in liver fibrosis.
    Zubiete-Franco I; Fernández-Tussy P; Barbier-Torres L; Simon J; Fernández-Ramos D; Lopitz-Otsoa F; Gutiérrez-de Juan V; de Davalillo SL; Duce AM; Iruzubieta P; Taibo D; Crespo J; Caballeria J; Villa E; Aurrekoetxea I; Aspichueta P; Varela-Rey M; Lu SC; Mato JM; Beraza N; Delgado TC; Martínez-Chantar ML
    Hepatology; 2017 Feb; 65(2):694-709. PubMed ID: 28035772
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.
    Lan H; Tang Z; Jin H; Sun Y
    Sci Rep; 2016 Apr; 6():24218. PubMed ID: 27063292
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppressive role of neddylation in dendritic cells during Mycobacterium tuberculosis infection.
    Chadha A; Mehto S; Selvakumar A; Vashishta M; Kamble SS; Popli S; Raman R; Singh Y; Natarajan K
    Tuberculosis (Edinb); 2015 Sep; 95(5):599-607. PubMed ID: 26096160
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer.
    Barbier-Torres L; Delgado TC; García-Rodríguez JL; Zubiete-Franco I; Fernández-Ramos D; Buqué X; Cano A; Gutiérrez-de Juan V; Fernández-Domínguez I; Lopitz-Otsoa F; Fernández-Tussy P; Boix L; Bruix J; Villa E; Castro A; Lu SC; Aspichueta P; Xirodimas D; Varela-Rey M; Mato JM; Beraza N; Martínez-Chantar ML
    Oncotarget; 2015 Feb; 6(4):2509-23. PubMed ID: 25650664
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SAG/Rbx2-Dependent Neddylation Regulates T-Cell Responses.
    Mathewson ND; Fujiwara H; Wu SR; Toubai T; Oravecz-Wilson K; Sun Y; Rossi C; Zajac C; Sun Y; Reddy P
    Am J Pathol; 2016 Oct; 186(10):2679-91. PubMed ID: 27543965
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of NAE-dependent protein hyper-NEDDylation in cystic cholangiocytes halts cystogenesis in experimental models of polycystic liver disease.
    Lee-Law PY; Olaizola P; Caballero-Camino FJ; Izquierdo-Sanchez L; Rodrigues PM; Perugorria MJ; Azkargorta M; Elortza F; Martinez-Chantar ML; Aspichueta P; Marzioni M; Bujanda L; Drenth JPH; Banales JM
    United European Gastroenterol J; 2021 Sep; 9(7):848-859. PubMed ID: 34310849
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin signaling.
    van de Laar L; Buitenhuis M; Wensveen FM; Janssen HL; Coffer PJ; Woltman AM
    J Immunol; 2010 Jun; 184(12):6600-11. PubMed ID: 20488790
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neddylation Inhibition Activates the Extrinsic Apoptosis Pathway through ATF4-CHOP-DR5 Axis in Human Esophageal Cancer Cells.
    Chen P; Hu T; Liang Y; Li P; Chen X; Zhang J; Ma Y; Hao Q; Wang J; Zhang P; Zhang Y; Zhao H; Yang S; Yu J; Jeong LS; Qi H; Yang M; Hoffman RM; Dong Z; Jia L
    Clin Cancer Res; 2016 Aug; 22(16):4145-57. PubMed ID: 26983464
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DEPTOR suppresses the progression of esophageal squamous cell carcinoma and predicts poor prognosis.
    Ji YM; Zhou XF; Zhang J; Zheng X; Li SB; Wei ZQ; Liu T; Cheng DL; Liu P; Song K; Tan T; Zhu H; Guo JL
    Oncotarget; 2016 Mar; 7(12):14188-98. PubMed ID: 26893358
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer.
    Chen P; Hu T; Liang Y; Jiang Y; Pan Y; Li C; Zhang P; Wei D; Li P; Jeong LS; Chu Y; Qi H; Yang M; Hoffman RM; Dong Z; Jia L
    Oncotarget; 2015 Apr; 6(11):9002-17. PubMed ID: 25797246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tyrosine phosphorylation of DEPTOR functions as a molecular switch to activate mTOR signaling.
    M Gagné L; Morin N; Lavoie N; Bisson N; Lambert JP; Mallette FA; Huot MÉ
    J Biol Chem; 2021 Nov; 297(5):101291. PubMed ID: 34634301
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neddylation: a novel modulator of the tumor microenvironment.
    Zhou L; Jiang Y; Luo Q; Li L; Jia L
    Mol Cancer; 2019 Apr; 18(1):77. PubMed ID: 30943988
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth.
    Luo Z; Yu G; Lee HW; Li L; Wang L; Yang D; Pan Y; Ding C; Qian J; Wu L; Chu Y; Yi J; Wang X; Sun Y; Jeong LS; Liu J; Jia L
    Cancer Res; 2012 Jul; 72(13):3360-71. PubMed ID: 22562464
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DEPTOR-mTOR Signaling Is Critical for Lipid Metabolism and Inflammation Homeostasis of Lymphocytes in Human PBMC Culture.
    Xie QB; Liang Y; Yang M; Yang Y; Cen XM; Yin G
    J Immunol Res; 2017; 2017():5252840. PubMed ID: 28349073
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.