These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

287 related articles for article (PubMed ID: 27226027)

  • 21. CaMKII orchestrates endoplasmic reticulum stress and apoptosis in doxorubicin-induced cardiotoxicity by regulating the IRE1α/XBP1s pathway.
    Kong L; Zhang Y; Ning J; Xu C; Wang Z; Yang J; Yang L
    J Cell Mol Med; 2022 Oct; 26(20):5303-5314. PubMed ID: 36111515
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Emerging roles for the ER stress sensor IRE1α in metabolic regulation and disease.
    Huang S; Xing Y; Liu Y
    J Biol Chem; 2019 Dec; 294(49):18726-18741. PubMed ID: 31666338
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Phosphorylation at Ser
    Li Y; Huang S; Wang J; Dai J; Cai J; Yan S; Huang Z; He S; Wang P; Liu J; Liu Y
    J Biol Chem; 2022 Jun; 298(6):101997. PubMed ID: 35500653
    [TBL] [Abstract][Full Text] [Related]  

  • 24. IRE1α prevents hepatic steatosis by processing and promoting the degradation of select microRNAs.
    Wang JM; Qiu Y; Yang Z; Kim H; Qian Q; Sun Q; Zhang C; Yin L; Fang D; Back SH; Kaufman RJ; Yang L; Zhang K
    Sci Signal; 2018 May; 11(530):. PubMed ID: 29764990
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability.
    Liu J; Wang Y; Song L; Zeng L; Yi W; Liu T; Chen H; Wang M; Ju Z; Cong YS
    Nat Commun; 2017 Jan; 8():14186. PubMed ID: 28128204
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Nicotinic acetylcholine receptor signaling regulates inositol-requiring enzyme 1α activation to protect β-cells against terminal unfolded protein response under irremediable endoplasmic reticulum stress.
    Ishibashi T; Morita S; Kishimoto S; Uraki S; Takeshima K; Furukawa Y; Inaba H; Ariyasu H; Iwakura H; Furuta H; Nishi M; Papa FR; Akamizu T
    J Diabetes Investig; 2020 Jul; 11(4):801-813. PubMed ID: 31925927
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Induction of the Endoplasmic-Reticulum-Stress Response: MicroRNA-34a Targeting of the IRE1α-Branch.
    Krammes L; Hart M; Rheinheimer S; Diener C; Menegatti J; Grässer F; Keller A; Meese E
    Cells; 2020 Jun; 9(6):. PubMed ID: 32531952
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma.
    Mimura N; Fulciniti M; Gorgun G; Tai YT; Cirstea D; Santo L; Hu Y; Fabre C; Minami J; Ohguchi H; Kiziltepe T; Ikeda H; Kawano Y; French M; Blumenthal M; Tam V; Kertesz NL; Malyankar UM; Hokenson M; Pham T; Zeng Q; Patterson JB; Richardson PG; Munshi NC; Anderson KC
    Blood; 2012 Jun; 119(24):5772-81. PubMed ID: 22538852
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia.
    Sun H; Lin DC; Guo X; Kharabi Masouleh B; Gery S; Cao Q; Alkan S; Ikezoe T; Akiba C; Paquette R; Chien W; Müller-Tidow C; Jing Y; Agelopoulos K; Müschen M; Koeffler HP
    Oncotarget; 2016 Apr; 7(14):18736-49. PubMed ID: 26934650
    [TBL] [Abstract][Full Text] [Related]  

  • 30. An initial phase of JNK activation inhibits cell death early in the endoplasmic reticulum stress response.
    Brown M; Strudwick N; Suwara M; Sutcliffe LK; Mihai AD; Ali AA; Watson JN; Schröder M
    J Cell Sci; 2016 Jun; 129(12):2317-2328. PubMed ID: 27122189
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Ginkgolide K protects the heart against endoplasmic reticulum stress injury by activating the inositol-requiring enzyme 1α/X box-binding protein-1 pathway.
    Wang S; Wang Z; Fan Q; Guo J; Galli G; Du G; Wang X; Xiao W
    Br J Pharmacol; 2016 Aug; 173(15):2402-18. PubMed ID: 27186946
    [TBL] [Abstract][Full Text] [Related]  

  • 32. METABOLISM. S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction.
    Yang L; Calay ES; Fan J; Arduini A; Kunz RC; Gygi SP; Yalcin A; Fu S; Hotamisligil GS
    Science; 2015 Jul; 349(6247):500-6. PubMed ID: 26228140
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes.
    Montibeller L; de Belleroche J
    Cell Stress Chaperones; 2018 Sep; 23(5):897-912. PubMed ID: 29725981
    [TBL] [Abstract][Full Text] [Related]  

  • 34. IRE1alpha controls cyclin A1 expression and promotes cell proliferation through XBP-1.
    Thorpe JA; Schwarze SR
    Cell Stress Chaperones; 2010 Sep; 15(5):497-508. PubMed ID: 20013084
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Hepatocyte-specific deletion of XBP1 sensitizes mice to liver injury through hyperactivation of IRE1α.
    Duwaerts CC; Siao K; Soon RK; Her C; Iwawaki T; Kohno K; Mattis AN; Maher JJ
    Cell Death Differ; 2021 May; 28(5):1455-1465. PubMed ID: 33219328
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Small molecule inhibition of IRE1α kinase/RNase has anti-fibrotic effects in the lung.
    Thamsen M; Ghosh R; Auyeung VC; Brumwell A; Chapman HA; Backes BJ; Perara G; Maly DJ; Sheppard D; Papa FR
    PLoS One; 2019; 14(1):e0209824. PubMed ID: 30625178
    [TBL] [Abstract][Full Text] [Related]  

  • 37. IRE1α pathway of endoplasmic reticulum stress induces neuronal apoptosis in the locus coeruleus of rats under single prolonged stress.
    Zhao W; Han F; Shi Y
    Prog Neuropsychopharmacol Biol Psychiatry; 2016 Aug; 69():11-8. PubMed ID: 27059130
    [TBL] [Abstract][Full Text] [Related]  

  • 38. HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction.
    Gupta S; Deepti A; Deegan S; Lisbona F; Hetz C; Samali A
    PLoS Biol; 2010 Jul; 8(7):e1000410. PubMed ID: 20625543
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Inhibition of ER stress by targeting the IRE1α-TXNDC5 pathway alleviates crystalline silica-induced pulmonary fibrosis.
    Chen X; Li C; Liu J; He Y; Wei Y; Chen J
    Int Immunopharmacol; 2021 Jun; 95():107519. PubMed ID: 33691254
    [TBL] [Abstract][Full Text] [Related]  

  • 40. IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling.
    Chen C; Zhang X
    J Transl Med; 2017 Feb; 15(1):42. PubMed ID: 28222747
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.