176 related articles for article (PubMed ID: 27226387)
1. Biochemical and Cellular Characterization and Inhibitor Discovery of Pseudomonas aeruginosa 15-Lipoxygenase.
Deschamps JD; Ogunsola AF; Jameson JB; Yasgar A; Flitter BA; Freedman CJ; Melvin JA; Nguyen JV; Maloney DJ; Jadhav A; Simeonov A; Bomberger JM; Holman TR
Biochemistry; 2016 Jun; 55(23):3329-40. PubMed ID: 27226387
[TBL] [Abstract][Full Text] [Related]
2. 5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1.
Green AR; Freedman C; Tena J; Tourdot BE; Liu B; Holinstat M; Holman TR
Biochemistry; 2018 Dec; 57(48):6726-6734. PubMed ID: 30407793
[TBL] [Abstract][Full Text] [Related]
3. Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa.
Banthiya S; Kalms J; Galemou Yoga E; Ivanov I; Carpena X; Hamberg M; Kuhn H; Scheerer P
Biochim Biophys Acta; 2016 Nov; 1861(11):1681-1692. PubMed ID: 27500637
[TBL] [Abstract][Full Text] [Related]
4. The opportunistic pathogen Pseudomonas aeruginosa carries a secretable arachidonate 15-lipoxygenase.
Vance RE; Hong S; Gronert K; Serhan CN; Mekalanos JJ
Proc Natl Acad Sci U S A; 2004 Feb; 101(7):2135-9. PubMed ID: 14766977
[TBL] [Abstract][Full Text] [Related]
5.
Morello E; Pérez-Berezo T; Boisseau C; Baranek T; Guillon A; Bréa D; Lanotte P; Carpena X; Pietrancosta N; Hervé V; Ramphal R; Cenac N; Si-Tahar M
Front Microbiol; 2019; 10():1826. PubMed ID: 31474948
[No Abstract] [Full Text] [Related]
6. A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2.
Jameson JB; Kantz A; Schultz L; Kalyanaraman C; Jacobson MP; Maloney DJ; Jadhav A; Simeonov A; Holman TR
PLoS One; 2014; 9(8):e104094. PubMed ID: 25111178
[TBL] [Abstract][Full Text] [Related]
7. Strict Regiospecificity of Human Epithelial 15-Lipoxygenase-2 Delineates Its Transcellular Synthesis Potential.
Green AR; Barbour S; Horn T; Carlos J; Raskatov JA; Holman TR
Biochemistry; 2016 May; 55(20):2832-40. PubMed ID: 27145229
[TBL] [Abstract][Full Text] [Related]
8. Inhibitory and mechanistic investigations of oxo-lipids with human lipoxygenase isozymes.
Armstrong MM; Diaz G; Kenyon V; Holman TR
Bioorg Med Chem; 2014 Aug; 22(15):4293-7. PubMed ID: 24924423
[TBL] [Abstract][Full Text] [Related]
9. Understanding the Mechanism of the Hydrogen Abstraction from Arachidonic Acid Catalyzed by the Human Enzyme 15-Lipoxygenase-2. A Quantum Mechanics/Molecular Mechanics Free Energy Simulation.
Suardíaz R; Jambrina PG; Masgrau L; González-Lafont À; Rosta E; Lluch JM
J Chem Theory Comput; 2016 Apr; 12(4):2079-90. PubMed ID: 26918937
[TBL] [Abstract][Full Text] [Related]
10. Kinetic investigation of human 5-lipoxygenase with arachidonic acid.
Mittal M; Kumar RB; Balagunaseelan N; Hamberg M; Jegerschöld C; Rådmark O; Haeggström JZ; Rinaldo-Matthis A
Bioorg Med Chem Lett; 2016 Aug; 26(15):3547-51. PubMed ID: 27363940
[TBL] [Abstract][Full Text] [Related]
11. The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity.
Kalms J; Banthiya S; Galemou Yoga E; Hamberg M; Holzhutter HG; Kuhn H; Scheerer P
Biochim Biophys Acta Mol Cell Biol Lipids; 2017 May; 1862(5):463-473. PubMed ID: 28093240
[TBL] [Abstract][Full Text] [Related]
12. Kinetic and structural investigations of the allosteric site in human epithelial 15-lipoxygenase-2.
Wecksler AT; Kenyon V; Garcia NK; Deschamps JD; van der Donk WA; Holman TR
Biochemistry; 2009 Sep; 48(36):8721-30. PubMed ID: 19645454
[TBL] [Abstract][Full Text] [Related]
13. A potent and selective inhibitor targeting human and murine 12/15-LOX.
Armstrong MM; Freedman CJ; Jung JE; Zheng Y; Kalyanaraman C; Jacobson MP; Simeonov A; Maloney DJ; van Leyen K; Jadhav A; Holman TR
Bioorg Med Chem; 2016 Mar; 24(6):1183-90. PubMed ID: 26899595
[TBL] [Abstract][Full Text] [Related]
14. Activity-Based Probes for 15-Lipoxygenase-1.
Eleftheriadis N; Thee SA; Zwinderman MR; Leus NG; Dekker FJ
Angew Chem Int Ed Engl; 2016 Sep; 55(40):12300-5. PubMed ID: 27612308
[TBL] [Abstract][Full Text] [Related]
15. Characterization of arachidonic-acid-metabolizing enzymes in adult Schistisoma mansoni.
Abdel Baset H; O'Neill GP; Ford-Hutchinson AW
Mol Biochem Parasitol; 1995 Jul; 73(1-2):31-41. PubMed ID: 8577345
[TBL] [Abstract][Full Text] [Related]
16. Kinetic investigations of the rate-limiting step in human 12- and 15-lipoxygenase.
Segraves EN; Holman TR
Biochemistry; 2003 May; 42(18):5236-43. PubMed ID: 12731864
[TBL] [Abstract][Full Text] [Related]
17. Improvement of lipoxygenase inhibition by octapeptides.
Schurink M; van Berkel WJ; Wichers HJ; Boeriu CG
Peptides; 2007 Dec; 28(12):2268-75. PubMed ID: 17996330
[TBL] [Abstract][Full Text] [Related]
18. Development of novel peptide inhibitor of Lipoxygenase based on biochemical and BIAcore evidences.
Somvanshi RK; Singh AK; Saxena M; Mishra B; Dey S
Biochim Biophys Acta; 2008 Nov; 1784(11):1812-7. PubMed ID: 18691678
[TBL] [Abstract][Full Text] [Related]
19. Alterations of lipoxygenase specificity by targeted substrate modification and site-directed mutagenesis.
Walther M; Ivanov I; Myagkova G; Kuhn H
Chem Biol; 2001 Aug; 8(8):779-90. PubMed ID: 11514227
[TBL] [Abstract][Full Text] [Related]
20. Kinetic and structural investigations into the allosteric and pH effect on the substrate specificity of human epithelial 15-lipoxygenase-2.
Joshi N; Hoobler EK; Perry S; Diaz G; Fox B; Holman TR
Biochemistry; 2013 Nov; 52(45):8026-35. PubMed ID: 24171444
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
