BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

293 related articles for article (PubMed ID: 27233924)

  • 41. Management of organic impurities in small molecule medicinal products: Deriving safe limits for use in early development.
    Harvey J; Fleetwood A; Ogilvie R; Teasdale A; Wilcox P; Spanhaak S
    Regul Toxicol Pharmacol; 2017 Mar; 84():116-123. PubMed ID: 28038978
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Improvement of in vivo genotoxicity assessment: combination of acute tests and integration into standard toxicity testing.
    Rothfuss A; Honma M; Czich A; Aardema MJ; Burlinson B; Galloway S; Hamada S; Kirkland D; Heflich RH; Howe J; Nakajima M; O'Donovan M; Plappert-Helbig U; Priestley C; Recio L; Schuler M; Uno Y; Martus HJ
    Mutat Res; 2011 Aug; 723(2):108-20. PubMed ID: 21182982
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Determination of compound-specific acceptable daily intakes for 11 mutagenic carcinogens used in pharmaceutical synthesis.
    Ellis P; Kenyon M; Dobo K
    Regul Toxicol Pharmacol; 2013 Mar; 65(2):201-13. PubMed ID: 23228434
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Overall impact of the regulatory requirements for genotoxic impurities on the drug development process.
    Giordani A; Kobel W; Gally HU
    Eur J Pharm Sci; 2011 May; 43(1-2):1-15. PubMed ID: 21420491
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Toxicity assessment strategies, data requirements, and risk assessment approaches to derive health based guidance values for non-relevant metabolites of plant protection products.
    Dekant W; Melching-Kollmuss S; Kalberlah F
    Regul Toxicol Pharmacol; 2010 Mar; 56(2):135-42. PubMed ID: 19883711
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Application of the threshold of toxicological concern concept to pharmaceutical manufacturing operations.
    Dolan DG; Naumann BD; Sargent EV; Maier A; Dourson M
    Regul Toxicol Pharmacol; 2005 Oct; 43(1):1-9. PubMed ID: 16099564
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Classification of dermal sensitizers in pharmaceutical manufacturing.
    Winkler GC; Perino C; Araya SH; Bechter R; Kuster M; Lovsin Barle E
    Regul Toxicol Pharmacol; 2015 Aug; 72(3):501-5. PubMed ID: 26028366
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Toxicological evaluation of ergocalciferol, cholecalciferol, and their metabolites by a category approach.
    Tugcu G; Charehsaz M; Aydın A
    Drug Chem Toxicol; 2021 Nov; 44(6):661-667. PubMed ID: 31412708
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Derivation of an occupational exposure limit for an inhalation analgesic methoxyflurane (Penthrox(®)).
    Frangos J; Mikkonen A; Down C
    Regul Toxicol Pharmacol; 2016 Oct; 80():210-25. PubMed ID: 27181451
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Exposure-triggered reproductive toxicity testing under the REACH legislation: a proposal to define significant/relevant exposure.
    Bernauer U; Heinemeyer G; Heinrich-Hirsch B; Ulbrich B; Gundert-Remy U
    Toxicol Lett; 2008 Jan; 176(1):68-76. PubMed ID: 18068317
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Setting occupational exposure limits for unstudied pharmaceutical intermediates using an in vitro parallelogram approach.
    Maier MS
    Toxicol Mech Methods; 2011 Feb; 21(2):76-85. PubMed ID: 20156007
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Determination of a site-specific reference dose for methylmercury for fish-eating populations.
    Shipp AM; Gentry PR; Lawrence G; Van Landingham C; Covington T; Clewell HJ; Gribben K; Crump K
    Toxicol Ind Health; 2000 Nov; 16(9-10):335-438. PubMed ID: 11762928
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Considerations when deriving compound-specific limits for extractables and leachables from pharmaceutical products: Four case studies.
    Parris P; Martin EA; Stanard B; Glowienke S; Dolan DG; Li K; Binazon O; Giddings A; Whelan G; Masuda-Herrera M; Bercu J; Broschard T; Bruen U; Callis CM; Stults CLM; Erexson GL; Cruz MT; Nagao LM
    Regul Toxicol Pharmacol; 2020 Dec; 118():104802. PubMed ID: 33038429
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Mutagenicity assessment strategy for pharmaceutical intermediates to aid limit setting for occupational exposure.
    Araya S; Lovsin-Barle E; Glowienke S
    Regul Toxicol Pharmacol; 2015 Nov; 73(2):515-20. PubMed ID: 26454093
    [TBL] [Abstract][Full Text] [Related]  

  • 55. RIFM fragrance ingredient safety assessment, linalyl isobutyrate, CAS registry number 78-35-3.
    Api AM; Belsito D; Bhatia S; Bruze M; Calow P; Dagli ML; Dekant W; Fryer AD; Kromidas L; La Cava S; Lalko JF; Lapczynski A; Liebler DC; Miyachi Y; Politano VT; Ritacco G; Salvito D; Schultz TW; Shen J; Sipes IG; Wall B; Wilcox DK
    Food Chem Toxicol; 2015 Oct; 84 Suppl():S76-87. PubMed ID: 26423640
    [TBL] [Abstract][Full Text] [Related]  

  • 56. RIFM fragrance ingredient safety assessment, Linalyl isovalerate, CAS Registry Number 1118-27-0.
    Api AM; Belsito D; Bhatia S; Bruze M; Calow P; Dagli ML; Dekant W; Fryer AD; Kromidas L; La Cava S; Lalko JF; Lapczynski A; Liebler DC; Miyachi Y; Politano VT; Ritacco G; Salvito D; Schultz TW; Shen J; Sipes IG; Wall B; Wilcox DK
    Food Chem Toxicol; 2015 Oct; 84 Suppl():S88-99. PubMed ID: 26334794
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern.
    Laufersweiler MC; Gadagbui B; Baskerville-Abraham IM; Maier A; Willis A; Scialli AR; Carr GJ; Felter SP; Blackburn K; Daston G
    Regul Toxicol Pharmacol; 2012 Feb; 62(1):160-82. PubMed ID: 22019814
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Revision of the ICH guideline on detection of toxicity to reproduction for medicinal products: SWOT analysis.
    Barrow P
    Reprod Toxicol; 2016 Sep; 64():57-63. PubMed ID: 27046733
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Human health risk assessment of chloroxylenol in liquid hand soap and dishwashing soap used by consumers and health-care professionals.
    Yost LJ; Rodricks JD; Turnbull D; DeLeo PC; Nash JF; Quiñones-Rivera A; Carlson PA
    Regul Toxicol Pharmacol; 2016 Oct; 80():116-24. PubMed ID: 27316554
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Establishing powder-handling workflow practices and standard operating procedures: compounding pharmacy and safety.
    Prince B; Lundevall J
    Int J Pharm Compd; 2014; 18(3):222-6. PubMed ID: 25306770
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.