These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 27236925)

  • 1. Screening of hepatitis C NS5B polymerase inhibitors containing benzothiadiazine core: a steered molecular dynamics.
    Nutho B; Meeprasert A; Chulapa M; Kungwan N; Rungrotmongkol T
    J Biomol Struct Dyn; 2017 Jun; 35(8):1743-1757. PubMed ID: 27236925
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insight into the structural requirements of benzothiadiazine scaffold-based derivatives as hepatitis C virus NS5B polymerase inhibitors using 3D-QSAR, molecular docking and molecular dynamics.
    Zhang HX; Li Y; Wang X; Xiao ZT; Wang YH
    Curr Med Chem; 2011; 18(26):4019-28. PubMed ID: 21824089
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular modeling and residue interaction network studies on the mechanism of binding and resistance of the HCV NS5B polymerase mutants to VX-222 and ANA598.
    Xue W; Jiao P; Liu H; Yao X
    Antiviral Res; 2014 Apr; 104():40-51. PubMed ID: 24462692
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Combined 3D-QSAR, molecular docking, molecular dynamics simulation, and binding free energy calculation studies on the 5-hydroxy-2H-pyridazin-3-one derivatives as HCV NS5B polymerase inhibitors.
    Yu H; Fang Y; Lu X; Liu Y; Zhang H
    Chem Biol Drug Des; 2014 Jan; 83(1):89-105. PubMed ID: 23941500
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In silico screening for potent inhibitors against the NS3/4A protease of hepatitis C virus.
    Meeprasert A; Rungrotmongkol T; Li MS; Hannongbua S
    Curr Pharm Des; 2014; 20(21):3465-77. PubMed ID: 24001230
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recent advances in drug discovery of benzothiadiazine and related analogs as HCV NS5B polymerase inhibitors.
    Das D; Hong J; Chen SH; Wang G; Beigelman L; Seiwert SD; Buckman BO
    Bioorg Med Chem; 2011 Aug; 19(16):4690-703. PubMed ID: 21798747
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Non-nucleoside inhibitors of HCV NS5B polymerase. Part 1: Synthetic and computational exploration of the binding modes of benzothiadiazine and 1,4-benzothiazine HCV NS5b polymerase inhibitors.
    Hendricks RT; Fell JB; Blake JF; Fischer JP; Robinson JE; Spencer SR; Stengel PJ; Bernacki AL; Leveque VJ; Le Pogam S; Rajyaguru S; Najera I; Josey JA; Harris JR; Swallow S
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3637-41. PubMed ID: 19447623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of novel natural flavonoids as potent antiviral candidates against hepatitis C virus NS5B polymerase.
    Akher FB; Farrokhzadeh A; Ramharack P; Shunmugam L; Van Heerden FR; Soliman MES
    Med Hypotheses; 2019 Nov; 132():109359. PubMed ID: 31466018
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multiple virtual screening approaches for finding new hepatitis C virus RNA-dependent RNA polymerase inhibitors: structure-based screens and molecular dynamics for the pursue of new poly pharmacological inhibitors.
    Elhefnawi M; ElGamacy M; Fares M
    BMC Bioinformatics; 2012; 13 Suppl 17(Suppl 17):S5. PubMed ID: 23282180
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiple e-pharmacophore modeling, 3D-QSAR, and high-throughput virtual screening of hepatitis C virus NS5B polymerase inhibitors.
    Therese PJ; Manvar D; Kondepudi S; Battu MB; Sriram D; Basu A; Yogeeswari P; Kaushik-Basu N
    J Chem Inf Model; 2014 Feb; 54(2):539-52. PubMed ID: 24460140
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of NS5B Polymerase Activity of Hepatitis C Virus by Target Specific Phytotherapeutics: An In-Silico Molecular Dynamics Approach.
    Dhanasekaran S; Selvadoss PP; Manoharan SS; Jeyabalan S; Yaraguppi DA; Choudhury AA; Rajeswari VD; Ramanathan G; Thamaraikani T; Sekar M; Subramaniyan V; Shing WL
    Cell Biochem Biophys; 2024 Sep; 82(3):2473-2492. PubMed ID: 39042185
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In silico identification of novel SARS-COV-2 2'-O-methyltransferase (nsp16) inhibitors: structure-based virtual screening, molecular dynamics simulation and MM-PBSA approaches.
    El Hassab MA; Ibrahim TM; Al-Rashood ST; Alharbi A; Eskandrani RO; Eldehna WM
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):727-736. PubMed ID: 33685335
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel Guanosine Derivatives as Anti-HCV NS5b Polymerase: A QSAR and Molecular Docking Study.
    Elfiky AA
    Med Chem; 2019; 15(2):130-137. PubMed ID: 30324891
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Distinct Characteristic Binding Modes of Benzofuran Core Inhibitors to Diverse Genotypes of Hepatitis C Virus NS5B Polymerase: A Molecular Simulation Study.
    Han D; Zhao F; Chen Y; Xue Y; Bao K; Chang Y; Lu J; Wang M; Liu T; Gao Q; Cui W; Xu Y
    Int J Mol Sci; 2024 Jul; 25(15):. PubMed ID: 39125602
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparative Molecular Field Analysis and Molecular Docking Studies on Quinolinone Derivatives Indicate Potential Hepatitis C Virus Inhibitors.
    Malathi K; Ramaiah S; Anbarasu A
    Cell Biochem Biophys; 2019 Jun; 77(2):139-156. PubMed ID: 30796723
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Probing the "fingers" domain binding pocket of Hepatitis C virus NS5B RdRp and D559G resistance mutation via molecular docking, molecular dynamics simulation and binding free energy calculations.
    Manjula S; Sivanandam M; Kumaradhas P
    J Biomol Struct Dyn; 2019 Jun; 37(9):2440-2456. PubMed ID: 30047829
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B.
    Bessa LM; Launay H; Dujardin M; Cantrelle FX; Lippens G; Landrieu I; Schneider R; Hanoulle X
    J Biol Chem; 2017 Nov; 292(44):18024-18043. PubMed ID: 28912275
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-based virtual screening, synthesis and SAR of novel inhibitors of hepatitis C virus NS5B polymerase.
    Talele TT; Arora P; Kulkarni SS; Patel MR; Singh S; Chudayeu M; Kaushik-Basu N
    Bioorg Med Chem; 2010 Jul; 18(13):4630-8. PubMed ID: 20627595
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combination of pharmacophore hypothesis and molecular docking to identify novel inhibitors of HCV NS5B polymerase.
    Harikishore A; Li E; Lee JJ; Cho NJ; Yoon HS
    Mol Divers; 2015 Aug; 19(3):529-39. PubMed ID: 25862642
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel 4-thiazolidinones as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase.
    Çakir G; Küçükgüzel İ; Guhamazumder R; Tatar E; Manvar D; Basu A; Patel BA; Zia J; Talele TT; Kaushik-Basu N
    Arch Pharm (Weinheim); 2015 Jan; 348(1):10-22. PubMed ID: 25449674
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.