BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

555 related articles for article (PubMed ID: 27246539)

  • 1. Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy.
    Incio J; Liu H; Suboj P; Chin SM; Chen IX; Pinter M; Ng MR; Nia HT; Grahovac J; Kao S; Babykutty S; Huang Y; Jung K; Rahbari NN; Han X; Chauhan VP; Martin JD; Kahn J; Huang P; Desphande V; Michaelson J; Michelakos TP; Ferrone CR; Soares R; Boucher Y; Fukumura D; Jain RK
    Cancer Discov; 2016 Aug; 6(8):852-69. PubMed ID: 27246539
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages.
    Incio J; Suboj P; Chin SM; Vardam-Kaur T; Liu H; Hato T; Babykutty S; Chen I; Deshpande V; Jain RK; Fukumura D
    PLoS One; 2015; 10(12):e0141392. PubMed ID: 26641266
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tumor-Stroma IL1β-IRAK4 Feedforward Circuitry Drives Tumor Fibrosis, Chemoresistance, and Poor Prognosis in Pancreatic Cancer.
    Zhang D; Li L; Jiang H; Li Q; Wang-Gillam A; Yu J; Head R; Liu J; Ruzinova MB; Lim KH
    Cancer Res; 2018 Apr; 78(7):1700-1712. PubMed ID: 29363544
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibiting tumor necrosis factor-alpha diminishes desmoplasia and inflammation to overcome chemoresistance in pancreatic ductal adenocarcinoma.
    Zhao X; Fan W; Xu Z; Chen H; He Y; Yang G; Yang G; Hu H; Tang S; Wang P; Zhang Z; Xu P; Yu M
    Oncotarget; 2016 Dec; 7(49):81110-81122. PubMed ID: 27835602
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Desmoplasia suppression by metformin-mediated AMPK activation inhibits pancreatic cancer progression.
    Duan W; Chen K; Jiang Z; Chen X; Sun L; Li J; Lei J; Xu Q; Ma J; Li X; Han L; Wang Z; Wu Z; Wang F; Wu E; Ma Q; Ma Z
    Cancer Lett; 2017 Jan; 385():225-233. PubMed ID: 27773749
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.
    Kaneda MM; Cappello P; Nguyen AV; Ralainirina N; Hardamon CR; Foubert P; Schmid MC; Sun P; Mose E; Bouvet M; Lowy AM; Valasek MA; Sasik R; Novelli F; Hirsch E; Varner JA
    Cancer Discov; 2016 Aug; 6(8):870-85. PubMed ID: 27179037
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tumor Cell-Derived IL1β Promotes Desmoplasia and Immune Suppression in Pancreatic Cancer.
    Das S; Shapiro B; Vucic EA; Vogt S; Bar-Sagi D
    Cancer Res; 2020 Mar; 80(5):1088-1101. PubMed ID: 31915130
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.
    Shi Y; Gao W; Lytle NK; Huang P; Yuan X; Dann AM; Ridinger-Saison M; DelGiorno KE; Antal CE; Liang G; Atkins AR; Erikson G; Sun H; Meisenhelder J; Terenziani E; Woo G; Fang L; Santisakultarm TP; Manor U; Xu R; Becerra CR; Borazanci E; Von Hoff DD; Grandgenett PM; Hollingsworth MA; Leblanc M; Umetsu SE; Collisson EA; Scadeng M; Lowy AM; Donahue TR; Reya T; Downes M; Evans RM; Wahl GM; Pawson T; Tian R; Hunter T
    Nature; 2019 May; 569(7754):131-135. PubMed ID: 30996350
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The critical roles of activated stellate cells-mediated paracrine signaling, metabolism and onco-immunology in pancreatic ductal adenocarcinoma.
    Fu Y; Liu S; Zeng S; Shen H
    Mol Cancer; 2018 Feb; 17(1):62. PubMed ID: 29458370
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment.
    Gomez-Chou SB; Swidnicka-Siergiejko AK; Badi N; Chavez-Tomar M; Lesinski GB; Bekaii-Saab T; Farren MR; Mace TA; Schmidt C; Liu Y; Deng D; Hwang RF; Zhou L; Moore T; Chatterjee D; Wang H; Leng X; Arlinghaus RB; Logsdon CD; Cruz-Monserrate Z
    Cancer Res; 2017 May; 77(10):2647-2660. PubMed ID: 28249896
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells.
    Nagathihalli NS; Castellanos JA; VanSaun MN; Dai X; Ambrose M; Guo Q; Xiong Y; Merchant NB
    Oncotarget; 2016 Oct; 7(40):65982-65992. PubMed ID: 27602757
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma.
    Ene-Obong A; Clear AJ; Watt J; Wang J; Fatah R; Riches JC; Marshall JF; Chin-Aleong J; Chelala C; Gribben JG; Ramsay AG; Kocher HM
    Gastroenterology; 2013 Nov; 145(5):1121-32. PubMed ID: 23891972
    [TBL] [Abstract][Full Text] [Related]  

  • 13. p110γ deficiency protects against pancreatic carcinogenesis yet predisposes to diet-induced hepatotoxicity.
    Torres C; Mancinelli G; Cordoba-Chacon J; Viswakarma N; Castellanos K; Grimaldo S; Kumar S; Principe D; Dorman MJ; McKinney R; Hirsch E; Dawson D; Munshi HG; Rana A; Grippo PJ
    Proc Natl Acad Sci U S A; 2019 Jul; 116(29):14724-14733. PubMed ID: 31266893
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer.
    Zhang Y; Liu L; Fan P; Bauer N; Gladkich J; Ryschich E; Bazhin AV; Giese NA; Strobel O; Hackert T; Hinz U; Gross W; Fortunato F; Herr I
    Oncotarget; 2015 Apr; 6(12):9999-10015. PubMed ID: 25846752
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Involvement of angiotensin II type 2 receptor (AT2R) signaling in human pancreatic ductal adenocarcinoma (PDAC): a novel AT2R agonist effectively attenuates growth of PDAC grafts in mice.
    Ishiguro S; Yoshimura K; Tsunedomi R; Oka M; Takao S; Inui M; Kawabata A; Wall T; Magafa V; Cordopatis P; Tzakos AG; Tamura M
    Cancer Biol Ther; 2015; 16(2):307-16. PubMed ID: 25756513
    [TBL] [Abstract][Full Text] [Related]  

  • 16. IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma.
    Biffi G; Oni TE; Spielman B; Hao Y; Elyada E; Park Y; Preall J; Tuveson DA
    Cancer Discov; 2019 Feb; 9(2):282-301. PubMed ID: 30366930
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.
    Nagathihalli NS; Castellanos JA; Shi C; Beesetty Y; Reyzer ML; Caprioli R; Chen X; Walsh AJ; Skala MC; Moses HL; Merchant NB
    Gastroenterology; 2015 Dec; 149(7):1932-1943.e9. PubMed ID: 26255562
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ESE3-positive PSCs drive pancreatic cancer fibrosis, chemoresistance and poor prognosis via tumour-stromal IL-1β/NF-κB/ESE3 signalling axis.
    Zhao T; Xiao D; Jin F; Sun X; Yu J; Wang H; Liu J; Cai W; Huang C; Wang X; Gao S; Liu Z; Yang S; Gao C; Hao J
    Br J Cancer; 2022 Nov; 127(8):1461-1472. PubMed ID: 35986089
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pancreatic stellate cell: Pandora's box for pancreatic disease biology.
    Bynigeri RR; Jakkampudi A; Jangala R; Subramanyam C; Sasikala M; Rao GV; Reddy DN; Talukdar R
    World J Gastroenterol; 2017 Jan; 23(3):382-405. PubMed ID: 28210075
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.
    Ijichi H; Chytil A; Gorska AE; Aakre ME; Bierie B; Tada M; Mohri D; Miyabayashi K; Asaoka Y; Maeda S; Ikenoue T; Tateishi K; Wright CV; Koike K; Omata M; Moses HL
    J Clin Invest; 2011 Oct; 121(10):4106-17. PubMed ID: 21926469
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.