722 related articles for article (PubMed ID: 27247382)
1. Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy.
Moore AS; Holzbaur EL
Proc Natl Acad Sci U S A; 2016 Jun; 113(24):E3349-58. PubMed ID: 27247382
[TBL] [Abstract][Full Text] [Related]
2. The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy.
Heo JM; Ordureau A; Paulo JA; Rinehart J; Harper JW
Mol Cell; 2015 Oct; 60(1):7-20. PubMed ID: 26365381
[TBL] [Abstract][Full Text] [Related]
3. Temporal dynamics of PARK2/parkin and OPTN/optineurin recruitment during the mitophagy of damaged mitochondria.
Wong YC; Holzbaur EL
Autophagy; 2015; 11(2):422-4. PubMed ID: 25801386
[TBL] [Abstract][Full Text] [Related]
4. Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.
Wong YC; Holzbaur EL
Proc Natl Acad Sci U S A; 2014 Oct; 111(42):E4439-48. PubMed ID: 25294927
[TBL] [Abstract][Full Text] [Related]
5. Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria.
Richter B; Sliter DA; Herhaus L; Stolz A; Wang C; Beli P; Zaffagnini G; Wild P; Martens S; Wagner SA; Youle RJ; Dikic I
Proc Natl Acad Sci U S A; 2016 Apr; 113(15):4039-44. PubMed ID: 27035970
[TBL] [Abstract][Full Text] [Related]
6. ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy.
Harding O; Evans CS; Ye J; Cheung J; Maniatis T; Holzbaur ELF
Proc Natl Acad Sci U S A; 2021 Jun; 118(24):. PubMed ID: 34099552
[TBL] [Abstract][Full Text] [Related]
7. Spatiotemporal dynamics of autophagy receptors in selective mitophagy.
Moore AS; Holzbaur EL
Autophagy; 2016 Oct; 12(10):1956-1957. PubMed ID: 27484150
[TBL] [Abstract][Full Text] [Related]
8.
Wauters F; Cornelissen T; Imberechts D; Martin S; Koentjoro B; Sue C; Vangheluwe P; Vandenberghe W
Autophagy; 2020 Feb; 16(2):203-222. PubMed ID: 30945962
[TBL] [Abstract][Full Text] [Related]
9. Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism.
Shen WC; Li HY; Chen GC; Chern Y; Tu PH
Autophagy; 2015 Apr; 11(4):685-700. PubMed ID: 25484089
[TBL] [Abstract][Full Text] [Related]
10. The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.
Lazarou M; Sliter DA; Kane LA; Sarraf SA; Wang C; Burman JL; Sideris DP; Fogel AI; Youle RJ
Nature; 2015 Aug; 524(7565):309-314. PubMed ID: 26266977
[TBL] [Abstract][Full Text] [Related]
11. PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis.
Araya J; Tsubouchi K; Sato N; Ito S; Minagawa S; Hara H; Hosaka Y; Ichikawa A; Saito N; Kadota T; Yoshida M; Fujita Y; Utsumi H; Kobayashi K; Yanagisawa H; Hashimoto M; Wakui H; Ishikawa T; Numata T; Kaneko Y; Asano H; Yamashita M; Odaka M; Morikawa T; Nishimura SL; Nakayama K; Kuwano K
Autophagy; 2019 Mar; 15(3):510-526. PubMed ID: 30290714
[TBL] [Abstract][Full Text] [Related]
12. LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy.
Padman BS; Nguyen TN; Uoselis L; Skulsuppaisarn M; Nguyen LK; Lazarou M
Nat Commun; 2019 Jan; 10(1):408. PubMed ID: 30679426
[TBL] [Abstract][Full Text] [Related]
13. Role of Optineurin in the Mitochondrial Dysfunction: Potential Implications in Neurodegenerative Diseases and Cancer.
Weil R; Laplantine E; Curic S; Génin P
Front Immunol; 2018; 9():1243. PubMed ID: 29971063
[TBL] [Abstract][Full Text] [Related]
14. RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway.
Heo JM; Ordureau A; Swarup S; Paulo JA; Shen K; Sabatini DM; Harper JW
Sci Adv; 2018 Nov; 4(11):eaav0443. PubMed ID: 30627666
[TBL] [Abstract][Full Text] [Related]
15. Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.
Li F; Xu D; Wang Y; Zhou Z; Liu J; Hu S; Gong Y; Yuan J; Pan L
Autophagy; 2018; 14(1):66-79. PubMed ID: 29394115
[TBL] [Abstract][Full Text] [Related]
16. PINK1-mediated mitophagy maintains pluripotency through optineurin.
Wang C; Liu K; Cao J; Wang L; Zhao Q; Li Z; Zhang H; Chen Q; Zhao T
Cell Prolif; 2021 May; 54(5):e13034. PubMed ID: 33931895
[TBL] [Abstract][Full Text] [Related]
17. A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin.
Sirohi K; Kumari A; Radha V; Swarup G
PLoS One; 2015; 10(9):e0138289. PubMed ID: 26376340
[TBL] [Abstract][Full Text] [Related]
18. Optineurin-mediated mitophagy protects renal tubular epithelial cells against accelerated senescence in diabetic nephropathy.
Chen K; Dai H; Yuan J; Chen J; Lin L; Zhang W; Wang L; Zhang J; Li K; He Y
Cell Death Dis; 2018 Jan; 9(2):105. PubMed ID: 29367621
[TBL] [Abstract][Full Text] [Related]
19. Glaucoma-Associated Mutations in the Optineurin Gene Have Limited Impact on Parkin-Dependent Mitophagy.
Chernyshova K; Inoue K; Yamashita SI; Fukuchi T; Kanki T
Invest Ophthalmol Vis Sci; 2019 Aug; 60(10):3625-3635. PubMed ID: 31469402
[TBL] [Abstract][Full Text] [Related]
20. Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy.
Ordureau A; Heo JM; Duda DM; Paulo JA; Olszewski JL; Yanishevski D; Rinehart J; Schulman BA; Harper JW
Proc Natl Acad Sci U S A; 2015 May; 112(21):6637-42. PubMed ID: 25969509
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
