These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 27251120)

  • 1. Synthesis and evaluation of new 2-aminothiophenes against Mycobacterium tuberculosis.
    Thanna S; Knudson SE; Grzegorzewicz A; Kapil S; Goins CM; Ronning DR; Jackson M; Slayden RA; Sucheck SJ
    Org Biomol Chem; 2016 Jul; 14(25):6119-6133. PubMed ID: 27251120
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis.
    Wilson R; Kumar P; Parashar V; Vilchèze C; Veyron-Churlet R; Freundlich JS; Barnes SW; Walker JR; Szymonifka MJ; Marchiano E; Shenai S; Colangeli R; Jacobs WR; Neiditch MB; Kremer L; Alland D
    Nat Chem Biol; 2013 Aug; 9(8):499-506. PubMed ID: 23770708
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of 4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran] analogues against both active and dormant Mycobacterium tuberculosis.
    Alluri KK; Reshma RS; Suraparaju R; Gottapu S; Sriram D
    Bioorg Med Chem; 2018 May; 26(8):1462-1469. PubMed ID: 29501415
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In Vitro Effect of DFC-2 on Mycolic Acid Biosynthesis in
    Kim S; Seo H; Mahmud HA; Islam MI; Kim YS; Lyu J; Nam KW; Lee BE; Lee KI; Song HY
    J Microbiol Biotechnol; 2017 Nov; 27(11):1932-1941. PubMed ID: 28870005
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and anti-tubercular evaluation of new 2-acylated and 2-alkylated amino-5-(4-(benzyloxy)phenyl)thiophene-3-carboxylic acid derivatives. Part 1.
    Lu X; Wan B; Franzblau SG; You Q
    Eur J Med Chem; 2011 Sep; 46(9):3551-63. PubMed ID: 21641695
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of inhibitors targeting polyketide synthase 13 of Mycobacterium tuberculosis as antituberculosis drug leads.
    Wang X; Zhao W; Wang B; Ding W; Guo H; Zhao H; Meng J; Liu S; Lu Y; Liu Y; Zhang D
    Bioorg Chem; 2021 Sep; 114():105110. PubMed ID: 34175719
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Altered drug efflux under iron deprivation unveils abrogated MmpL3 driven mycolic acid transport and fluidity in mycobacteria.
    Pal R; Hameed S; Fatima Z
    Biometals; 2019 Feb; 32(1):49-63. PubMed ID: 30430296
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of thiophene based small molecules as potent inhibitors of Mycobacterium tuberculosis.
    Meena CL; Singh P; Shaliwal RP; Kumar V; Kumar A; Tiwari AK; Asthana S; Singh R; Mahajan D
    Eur J Med Chem; 2020 Dec; 208():112772. PubMed ID: 32920342
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In silico Design and Synthesis of Tetrahydropyrimidinones and Tetrahydropyrimidinethiones as Potential Thymidylate Kinase Inhibitors Exerting Anti-TB Activity Against
    Venugopala KN; Tratrat C; Pillay M; Chandrashekharappa S; Al-Attraqchi OHA; Aldhubiab BE; Attimarad M; Alwassil OI; Nair AB; Sreeharsha N; Venugopala R; Morsy MA; Haroun M; Kumalo HM; Odhav B; Mlisana K
    Drug Des Devel Ther; 2020; 14():1027-1039. PubMed ID: 32214795
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Editorial: Current status and perspective on drug targets in tubercle bacilli and drug design of antituberculous agents based on structure-activity relationship.
    Tomioka H
    Curr Pharm Des; 2014; 20(27):4305-6. PubMed ID: 24245755
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-Based Optimization of Coumestan Derivatives as Polyketide Synthase 13-Thioesterase(Pks13-TE) Inhibitors with Improved hERG Profiles for
    Zhang W; Lun S; Wang SS; Cai YP; Yang F; Tang J; Bishai WR; Yu LF
    J Med Chem; 2022 Oct; 65(19):13240-13252. PubMed ID: 36174223
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Drugs that inhibit mycolic acid biosynthesis in Mycobacterium tuberculosis.
    Schroeder EK; de Souza N; Santos DS; Blanchard JS; Basso LA
    Curr Pharm Biotechnol; 2002 Sep; 3(3):197-225. PubMed ID: 12164478
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IQG-607 abrogates the synthesis of mycolic acids and displays intracellular activity against Mycobacterium tuberculosis in infected macrophages.
    Rodrigues-Junior VS; dos Santos Junior AA; Villela AD; Belardinelli JM; Morbidoni HR; Basso LA; Campos MM; Santos DS
    Int J Antimicrob Agents; 2014 Jan; 43(1):82-5. PubMed ID: 24139881
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and investigation on the structure-activity relationships of N-substituted 2-aminothiazole derivatives as antitubercular agents.
    Pieroni M; Wan B; Cho S; Franzblau SG; Costantino G
    Eur J Med Chem; 2014 Jan; 72():26-34. PubMed ID: 24333612
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: toward in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis.
    Chollet A; Stigliani JL; Pasca MR; Mori G; Lherbet C; Constant P; Quémard A; Bernadou J; Pratviel G; Bernardes-Génisson V
    Chem Biol Drug Des; 2016 Nov; 88(5):740-755. PubMed ID: 27301022
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New approaches to target the mycolic acid biosynthesis pathway for the development of tuberculosis therapeutics.
    North EJ; Jackson M; Lee RE
    Curr Pharm Des; 2014; 20(27):4357-78. PubMed ID: 24245756
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and anti-tubercular activity of 2-nitroimidazooxazines with modification at the C-7 position as PA-824 analogs.
    Kang YG; Park CY; Shin H; Singh R; Arora G; Yu CM; Lee IY
    Bioorg Med Chem Lett; 2015 Sep; 25(17):3650-3. PubMed ID: 26199118
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An Antibacterial β-Lactone Kills Mycobacterium tuberculosis by Disrupting Mycolic Acid Biosynthesis.
    Lehmann J; Cheng TY; Aggarwal A; Park AS; Zeiler E; Raju RM; Akopian T; Kandror O; Sacchettini JC; Moody DB; Rubin EJ; Sieber SA
    Angew Chem Int Ed Engl; 2018 Jan; 57(1):348-353. PubMed ID: 29067779
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 1,3-Oxazine-2-one derived dual-targeted molecules against replicating and non-replicating forms of Mycobacterium tuberculosis.
    Velappan AB; Kesamsetty D; Datta D; Ma R; Hari N; Franzblau SG; Debnath J
    Eur J Med Chem; 2020 Dec; 208():112835. PubMed ID: 32977201
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and Antibacterial Activity of Mefloquine-Based Analogs Against Sensitive and Resistant Mycobacterium tuberculosis Strains.
    da Silva Araújo A; Moraes AM; Lourenço MCS; Pessoa CO; da Silva ET; de Souza MVN
    Curr Top Med Chem; 2019; 19(9):683-689. PubMed ID: 30836914
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.