BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 27251775)

  • 21. Regioselective C-H hydroxylation of omeprazole sulfide by Bacillus megaterium CYP102A1 to produce a human metabolite.
    Jang HH; Ryu SH; Le TK; Doan TT; Nguyen TH; Park KD; Yim DE; Kim DH; Kang CK; Ahn T; Kang HS; Yun CH
    Biotechnol Lett; 2017 Jan; 39(1):105-112. PubMed ID: 27640009
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Regioselective hydroxylation of C(12)-C(15) fatty acids with fluorinated substituents by cytochrome P450 BM3.
    Chiang CH; Ramu R; Tu YJ; Yang CL; Ng KY; Luo WI; Chen CH; Lu YY; Liu CL; Yu SS
    Chemistry; 2013 Oct; 19(41):13680-91. PubMed ID: 24092541
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Screening of a minimal enriched P450 BM3 mutant library for hydroxylation of cyclic and acyclic alkanes.
    Weber E; Seifert A; Antonovici M; Geinitz C; Pleiss J; Urlacher VB
    Chem Commun (Camb); 2011 Jan; 47(3):944-6. PubMed ID: 21079837
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The role of the conserved threonine in P450 BM3 oxygen activation: substrate-determined hydroxylation activity of the Thr268Ala mutant.
    Cryle MJ; De Voss JJ
    Chembiochem; 2008 Jan; 9(2):261-6. PubMed ID: 18161730
    [TBL] [Abstract][Full Text] [Related]  

  • 25. An efficient route to selective bio-oxidation catalysts: an iterative approach comprising modeling, diversification, and screening, based on CYP102A1.
    Seifert A; Antonovici M; Hauer B; Pleiss J
    Chembiochem; 2011 Jun; 12(9):1346-51. PubMed ID: 21591046
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The full-length cytochrome P450 enzyme CYP102A1 dimerizes at its reductase domains and has flexible heme domains for efficient catalysis.
    Zhang H; Yokom AL; Cheng S; Su M; Hollenberg PF; Southworth DR; Osawa Y
    J Biol Chem; 2018 May; 293(20):7727-7736. PubMed ID: 29618513
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Rational re-design of the substrate binding site of flavocytochrome P450 BM3.
    Ost TW; Miles CS; Murdoch J; Cheung Y; Reid GA; Chapman SK; Munro AW
    FEBS Lett; 2000 Dec; 486(2):173-7. PubMed ID: 11113461
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Engineering cytochrome P450 BM3 of Bacillus megaterium for terminal oxidation of palmitic acid.
    Brühlmann F; Fourage L; Ullmann C; Haefliger OP; Jeckelmann N; Dubois C; Wahler D
    J Biotechnol; 2014 Aug; 184():17-26. PubMed ID: 24833423
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Functional interactions in cytochrome P450BM3: flavin semiquinone intermediates, role of NADP(H), and mechanism of electron transfer by the flavoprotein domain.
    Murataliev MB; Klein M; Fulco A; Feyereisen R
    Biochemistry; 1997 Jul; 36(27):8401-12. PubMed ID: 9204888
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
    Park SH; Kim DH; Kim D; Kim DH; Jung HC; Pan JG; Ahn T; Kim D; Yun CH
    Drug Metab Dispos; 2010 May; 38(5):732-9. PubMed ID: 20100815
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cytochrome P450 catalyzed oxidative hydroxylation of achiral organic compounds with simultaneous creation of two chirality centers in a single C-H activation step.
    Roiban GD; Agudo R; Reetz MT
    Angew Chem Int Ed Engl; 2014 Aug; 53(33):8659-63. PubMed ID: 24590553
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Synthesis of ω-hydroxy dodecanoic acid based on an engineered CYP153A fusion construct.
    Scheps D; Honda Malca S; Richter SM; Marisch K; Nestl BM; Hauer B
    Microb Biotechnol; 2013 Nov; 6(6):694-707. PubMed ID: 23941649
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Whole-cell microtiter plate screening assay for terminal hydroxylation of fatty acids by P450s.
    Weissenborn MJ; Notonier S; Lang SL; Otte KB; Herter S; Turner NJ; Flitsch SL; Hauer B
    Chem Commun (Camb); 2016 May; 52(36):6158-61. PubMed ID: 27074906
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Characterization of Two Self-Sufficient Monooxygenases, CYP102A15 and CYP102A170, as Long-Chain Fatty Acid Hydroxylases.
    Rimal H; Lee WH; Kim KH; Park H; Oh TJ
    J Microbiol Biotechnol; 2019 May; 30(5):777-784. PubMed ID: 32482945
    [TBL] [Abstract][Full Text] [Related]  

  • 35. An Enzymatic Route to α-Tocopherol Synthons: Aromatic Hydroxylation of Pseudocumene and Mesitylene with P450 BM3.
    Dennig A; Weingartner AM; Kardashliev T; Müller CA; Tassano E; Schürmann M; Ruff AJ; Schwaneberg U
    Chemistry; 2017 Dec; 23(71):17981-17991. PubMed ID: 28990705
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Altering the regioselectivity of the subterminal fatty acid hydroxylase P450 BM-3 towards gamma- and delta-positions.
    Dietrich M; Do TA; Schmid RD; Pleiss J; Urlacher VB
    J Biotechnol; 2009 Jan; 139(1):115-7. PubMed ID: 18984016
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Construction of a thermostable cytochrome P450 chimera derived from self-sufficient mesophilic parents.
    Eiben S; Bartelmäs H; Urlacher VB
    Appl Microbiol Biotechnol; 2007 Jul; 75(5):1055-61. PubMed ID: 17468867
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Regio- and enantioselective alkane hydroxylation with engineered cytochromes P450 BM-3.
    Peters MW; Meinhold P; Glieder A; Arnold FH
    J Am Chem Soc; 2003 Nov; 125(44):13442-50. PubMed ID: 14583039
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Application of engineered cytochrome P450 mutants as biocatalysts for the synthesis of benzylic and aromatic metabolites of fenamic acid NSAIDs.
    Venkataraman H; Verkade-Vreeker MC; Capoferri L; Geerke DP; Vermeulen NP; Commandeur JN
    Bioorg Med Chem; 2014 Oct; 22(20):5613-20. PubMed ID: 24999003
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Engineered P450 BM3 and cpADH5 coupled cascade reaction for β-oxo fatty acid methyl ester production in whole cells.
    Ensari Y; de Almeida Santos G; Ruff AJ; Schwaneberg U
    Enzyme Microb Technol; 2020 Aug; 138():109555. PubMed ID: 32527525
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.