BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 27251789)

  • 1. Phosphoproteomic Analyses of NRAS(G12) and NRAS(Q61) Mutant Melanocytes Reveal Increased CK2α Kinase Levels in NRAS(Q61) Mutant Cells.
    Posch C; Sanlorenzo M; Vujic I; Oses-Prieto JA; Cholewa BD; Kim ST; Ma J; Lai K; Zekhtser M; Esteve-Puig R; Green G; Chand S; Burlingame AL; Panzer-Grümayer R; Rappersberger K; Ortiz-Urda S
    J Invest Dermatol; 2016 Oct; 136(10):2041-2048. PubMed ID: 27251789
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NRAS, NRAS, Which Mutation Is Fairest of Them All?
    Grill C; Larue L
    J Invest Dermatol; 2016 Oct; 136(10):1936-1938. PubMed ID: 27664710
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo.
    Posch C; Moslehi H; Feeney L; Green GA; Ebaee A; Feichtenschlager V; Chong K; Peng L; Dimon MT; Phillips T; Daud AI; McCalmont TH; LeBoit PE; Ortiz-Urda S
    Proc Natl Acad Sci U S A; 2013 Mar; 110(10):4015-20. PubMed ID: 23431193
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The frequency and clinicopathological significance of NRAS mutations in primary cutaneous nodular melanoma in Indonesia.
    Rinonce HT; Sastri DJ; Trisnawati F; Kameswari B; Ferronika P; Irianiwati
    Cancer Rep (Hoboken); 2022 Jan; 5(1):e1454. PubMed ID: 34110110
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Growth suppression by dual BRAF(V600E) and NRAS(Q61) oncogene expression is mediated by SPRY4 in melanoma.
    Kumar R; Njauw CN; Reddy BY; Ji Z; Rajadurai A; Klebanov N; Tsao H
    Oncogene; 2019 May; 38(18):3504-3520. PubMed ID: 30651601
    [TBL] [Abstract][Full Text] [Related]  

  • 6. P53 and MITF/Bcl-2 identified as key pathways in the acquired resistance of NRAS-mutant melanoma to MEK inhibition.
    Najem A; Krayem M; Salès F; Hussein N; Badran B; Robert C; Awada A; Journe F; Ghanem GE
    Eur J Cancer; 2017 Sep; 83():154-165. PubMed ID: 28738256
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MIG6 Is MEK Regulated and Affects EGF-Induced Migration in Mutant NRAS Melanoma.
    Vu HL; Rosenbaum S; Capparelli C; Purwin TJ; Davies MA; Berger AC; Aplin AE
    J Invest Dermatol; 2016 Feb; 136(2):453-463. PubMed ID: 26967478
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Characterization of genetic alterations in primary human melanomas carrying BRAF or NRAS mutation].
    Lázár V
    Magy Onkol; 2013 Jun; 57(2):96-9. PubMed ID: 23795354
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Imaging Mass Spectrometry for the Classification of Melanoma Based on
    Casadonte R; Kriegsmann M; Kriegsmann K; Streit H; Meliß RR; Müller CSL; Kriegsmann J
    Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982192
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NRAS mutant melanoma: biological behavior and future strategies for therapeutic management.
    Fedorenko IV; Gibney GT; Smalley KS
    Oncogene; 2013 Jun; 32(25):3009-18. PubMed ID: 23069660
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synergistic effects of eIF4A and MEK inhibitors on proliferation of NRAS-mutant melanoma cell lines.
    Malka-Mahieu H; Girault I; Rubington M; Leriche M; Welsch C; Kamsu-Kom N; Zhao Q; Desaubry L; Vagner S; Robert C
    Cell Cycle; 2016 Sep; 15(18):2405-9. PubMed ID: 27533468
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MEK inhibition may increase survival of NRAS-mutated melanoma patients treated with checkpoint blockade: Results of a retrospective multicentre analysis of 364 patients.
    Kirchberger MC; Ugurel S; Mangana J; Heppt MV; Eigentler TK; Berking C; Schadendorf D; Schuler G; Dummer R; Heinzerling L
    Eur J Cancer; 2018 Jul; 98():10-16. PubMed ID: 29843107
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma.
    Hayes TK; Luo F; Cohen O; Goodale AB; Lee Y; Pantel S; Bagul M; Piccioni F; Root DE; Garraway LA; Meyerson M; Johannessen CM
    Cancer Res; 2019 May; 79(9):2352-2366. PubMed ID: 30819666
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of Wee1, AKT, and CDK4 underlies the efficacy of the HSP90 inhibitor XL888 in an in vivo model of NRAS-mutant melanoma.
    Haarberg HE; Paraiso KH; Wood E; Rebecca VW; Sondak VK; Koomen JM; Smalley KS
    Mol Cancer Ther; 2013 Jun; 12(6):901-12. PubMed ID: 23538902
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BRAF mutations are also associated with neurocutaneous melanocytosis and large/giant congenital melanocytic nevi.
    Salgado CM; Basu D; Nikiforova M; Bauer BS; Johnson D; Rundell V; Grunwaldt LJ; Reyes-Múgica M
    Pediatr Dev Pathol; 2015; 18(1):1-9. PubMed ID: 25490715
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RICTOR involvement in the PI3K/AKT pathway regulation in melanocytes and melanoma.
    Laugier F; Finet-Benyair A; André J; Rachakonda PS; Kumar R; Bensussan A; Dumaz N
    Oncotarget; 2015 Sep; 6(29):28120-31. PubMed ID: 26356562
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma.
    Vu HL; Aplin AE
    Mol Cancer Res; 2014 Oct; 12(10):1509-19. PubMed ID: 24962318
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Variation of mutant allele frequency in NRAS Q61 mutated melanomas.
    Hélias-Rodzewicz Z; Funck-Brentano E; Terrones N; Beauchet A; Zimmermann U; Marin C; Saiag P; Emile JF
    BMC Dermatol; 2017 Jul; 17(1):9. PubMed ID: 28668077
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The BRAF and NRAS mutation prevalence in dermoscopic subtypes of acquired naevi reveals constitutive mitogen-activated protein kinase pathway activation.
    Tan JM; Tom LN; Jagirdar K; Lambie D; Schaider H; Sturm RA; Soyer HP; Stark MS
    Br J Dermatol; 2018 Jan; 178(1):191-197. PubMed ID: 28714107
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Combined Inhibition of MEK and Plk1 Has Synergistic Antitumor Activity in NRAS Mutant Melanoma.
    Posch C; Cholewa BD; Vujic I; Sanlorenzo M; Ma J; Kim ST; Kleffel S; Schatton T; Rappersberger K; Gutteridge R; Ahmad N; Ortiz/Urda S
    J Invest Dermatol; 2015 Oct; 135(10):2475-2483. PubMed ID: 26016894
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.