These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

480 related articles for article (PubMed ID: 27252617)

  • 21. Donepezil Derivatives Targeting Amyloid-β Cascade in Alzheimer's Disease.
    Mezeiova E; Chalupova K; Nepovimova E; Gorecki L; Prchal L; Malinak D; Kuca K; Soukup O; Korabecny J
    Curr Alzheimer Res; 2019; 16(9):772-800. PubMed ID: 30819078
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Further Studies on Triazinoindoles as Potential Novel Multitarget-Directed Anti-Alzheimer's Agents.
    Patel DV; Patel NR; Kanhed AM; Teli DM; Patel KB; Gandhi PM; Patel SP; Chaudhary BN; Shah DB; Prajapati NK; Patel KV; Yadav MR
    ACS Chem Neurosci; 2020 Nov; 11(21):3557-3574. PubMed ID: 33073564
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease.
    Brunetti L; Leuci R; Carrieri A; Catto M; Occhineri S; Vinci G; Gambacorta L; Baltrukevich H; Chaves S; Laghezza A; Altomare CD; Tortorella P; Santos MA; Loiodice F; Piemontese L
    Eur J Med Chem; 2022 Jul; 237():114358. PubMed ID: 35462163
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Discovery of novel series of 2-substituted benzo[d]oxazol-5-amine derivatives as multi-target directed ligands for the treatment of Alzheimer's disease.
    Gutti G; Kakarla R; Kumar D; Beohar M; Ganeshpurkar A; Kumar A; Krishnamurthy S; Singh SK
    Eur J Med Chem; 2019 Nov; 182():111613. PubMed ID: 31437780
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Novel Donepezil-Arylsulfonamide Hybrids as Multitarget-Directed Ligands for Potential Treatment of Alzheimer's Disease.
    Queda F; Calò S; Gwizdala K; Magalhães JD; Cardoso SM; Chaves S; Piemontese L; Santos MA
    Molecules; 2021 Mar; 26(6):. PubMed ID: 33809771
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Development of multi-targetable chalcone derivatives bearing N-aryl piperazine moiety for the treatment of Alzheimer's disease.
    Bajad NG; Singh RB; T A G; Gutti G; Kumar A; Krishnamurthy S; Singh SK
    Bioorg Chem; 2024 Feb; 143():107082. PubMed ID: 38199142
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal structure and in-vitro biological evaluation.
    Manzoor S; Prajapati SK; Majumdar S; Raza MK; Gabr MT; Kumar S; Pal K; Rashid H; Kumar S; Krishnamurthy S; Hoda N
    Eur J Med Chem; 2021 Apr; 215():113224. PubMed ID: 33582578
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A molecular approach in drug development for Alzheimer's disease.
    Agatonovic-Kustrin S; Kettle C; Morton DW
    Biomed Pharmacother; 2018 Oct; 106():553-565. PubMed ID: 29990843
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Propargylamine-derived multitarget-directed ligands: fighting Alzheimer's disease with monoamine oxidase inhibitors.
    Bolea I; Gella A; Unzeta M
    J Neural Transm (Vienna); 2013 Jun; 120(6):893-902. PubMed ID: 23238976
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Recent Developments in Tacrine-based Hybrids as a Therapeutic Option for Alzheimer's Disease.
    Yamali C; Donmez S
    Mini Rev Med Chem; 2023; 23(7):869-880. PubMed ID: 36464869
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The development of advanced structural framework as multi-target-directed ligands for the treatment of Alzheimer's disease.
    Sang Z; Wang K; Shi J; Liu W; Cheng X; Zhu G; Wang Y; Zhao Y; Qiao Z; Wu A; Tan Z
    Eur J Med Chem; 2020 Apr; 192():112180. PubMed ID: 32131034
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A multifunctional anti-AD approach: Design, synthesis, X-ray crystal structure, biological evaluation and molecular docking of chrysin derivatives.
    Yang A; Liu C; Zhang H; Wu J; Shen R; Kou X
    Eur J Med Chem; 2022 Apr; 233():114216. PubMed ID: 35227980
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer's disease based on the fusion of donepezil and melatonin.
    Wang J; Wang ZM; Li XM; Li F; Wu JJ; Kong LY; Wang XB
    Bioorg Med Chem; 2016 Sep; 24(18):4324-4338. PubMed ID: 27460699
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design, Synthesis, and Pharmacological Evaluation of
    Kumar B; Dwivedi AR; Arora T; Raj K; Prashar V; Kumar V; Singh S; Prakash J; Kumar V
    ACS Chem Neurosci; 2022 Jul; 13(14):2122-2139. PubMed ID: 35797244
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Bolea I; Juárez-Jiménez J; de Los Ríos C; Chioua M; Pouplana R; Luque FJ; Unzeta M; Marco-Contelles J; Samadi A
    J Med Chem; 2011 Dec; 54(24):8251-70. PubMed ID: 22023459
    [TBL] [Abstract][Full Text] [Related]  

  • 36. In vitro and in vivo Biological Evaluation of Newly Tacrine-Selegiline Hybrids as Multi-Target Inhibitors of Cholinesterases and Monoamine Oxidases for Alzheimer's Disease.
    Huang ST; Luo JC; Zhong GH; Teng LP; Yang CY; Tang CL; Jing L; Zhou ZB; Liu J; Jiang N
    Drug Des Devel Ther; 2024; 18():133-159. PubMed ID: 38283137
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Hydroxytyrosol-Donepezil Hybrids Play a Protective Role in an In Vitro Induced Alzheimer's Disease Model and in Neuronal Differentiated Human SH-SY5Y Neuroblastoma Cells.
    Maiuolo J; Costanzo P; Masullo M; D'Errico A; Nasso R; Bonacci S; Mollace V; Oliverio M; Arcone R
    Int J Mol Sci; 2023 Aug; 24(17):. PubMed ID: 37686262
    [TBL] [Abstract][Full Text] [Related]  

  • 38. New phosphazine and phosphazide derivatives as multifunctional ligands targeting acetylcholinesterase and β-Amyloid aggregation for treatment of Alzheimer's disease.
    El-Sayed NF; El-Hussieny M; Ewies EF; Fouad MA; Boulos LS
    Bioorg Chem; 2020 Jan; 95():103499. PubMed ID: 31838287
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design, synthesis, and biological evaluation of thienopyrimidine derivatives as multifunctional agents against Alzheimer's disease.
    Eissa KI; Kamel MM; Mohamed LW; Doghish AS; Alnajjar R; Al-Karmalawy AA; Kassab AE
    Drug Dev Res; 2023 Aug; 84(5):937-961. PubMed ID: 37067008
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A Novel Multifunctional 5,6-Dimethoxy-Indanone-Chalcone-Carbamate Hybrids Alleviates Cognitive Decline in Alzheimer's Disease by Dual Inhibition of Acetylcholinesterase and Inflammation.
    Liu C; Sang Z; Pan H; Wu Q; Qiu Y; Shi J
    Front Aging Neurosci; 2022; 14():922650. PubMed ID: 35860673
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 24.