BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 27253695)

  • 1. Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair.
    Penterling C; Drexler GA; Böhland C; Stamp R; Wilke C; Braselmann H; Caldwell RB; Reindl J; Girst S; Greubel C; Siebenwirth C; Mansour WY; Borgmann K; Dollinger G; Unger K; Friedl AA
    PLoS One; 2016; 11(6):e0156599. PubMed ID: 27253695
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of the Histone H3K27 Demethylase UTX Enhances Tumor Cell Radiosensitivity.
    Rath BH; Waung I; Camphausen K; Tofilon PJ
    Mol Cancer Ther; 2018 May; 17(5):1070-1078. PubMed ID: 29483212
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histone H3 Lysine 9 Acetylation Obstructs ATM Activation and Promotes Ionizing Radiation Sensitivity in Normal Stem Cells.
    Meyer B; Fabbrizi MR; Raj S; Zobel CL; Hallahan DE; Sharma GG
    Stem Cell Reports; 2016 Dec; 7(6):1013-1022. PubMed ID: 27974220
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypoxia induces trimethylated H3 lysine 4 by inhibition of JARID1A demethylase.
    Zhou X; Sun H; Chen H; Zavadil J; Kluz T; Arita A; Costa M
    Cancer Res; 2010 May; 70(10):4214-21. PubMed ID: 20406991
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair.
    Gong F; Clouaire T; Aguirrebengoa M; Legube G; Miller KM
    J Cell Biol; 2017 Jul; 216(7):1959-1974. PubMed ID: 28572115
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repair.
    Hsiao KY; Mizzen CA
    J Mol Cell Biol; 2013 Jun; 5(3):157-65. PubMed ID: 23329852
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.
    DiTacchio L; Le HD; Vollmers C; Hatori M; Witcher M; Secombe J; Panda S
    Science; 2011 Sep; 333(6051):1881-5. PubMed ID: 21960634
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A.
    Chaturvedi CP; Somasundaram B; Singh K; Carpenedo RL; Stanford WL; Dilworth FJ; Brand M
    Proc Natl Acad Sci U S A; 2012 Nov; 109(46):18845-50. PubMed ID: 23112189
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance.
    Gale M; Sayegh J; Cao J; Norcia M; Gareiss P; Hoyer D; Merkel JS; Yan Q
    Oncotarget; 2016 Jun; 7(26):39931-39944. PubMed ID: 27224921
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4.
    Seiler DM; Rouquette J; Schmid VJ; Strickfaden H; Ottmann C; Drexler GA; Mazurek B; Greubel C; Hable V; Dollinger G; Cremer T; Friedl AA
    Chromosome Res; 2011 Oct; 19(7):883-99. PubMed ID: 21987186
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex.
    Nishibuchi G; Shibata Y; Hayakawa T; Hayakawa N; Ohtani Y; Sinmyozu K; Tagami H; Nakayama J
    J Biol Chem; 2014 Oct; 289(42):28956-70. PubMed ID: 25190814
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage.
    Marampon F; Gravina G; Ju X; Vetuschi A; Sferra R; Casimiro M; Pompili S; Festuccia C; Colapietro A; Gaudio E; Di Cesare E; Tombolini V; Pestell RG
    Oncotarget; 2016 Feb; 7(5):5383-400. PubMed ID: 26689991
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The KDM5 family of histone demethylases as targets in oncology drug discovery.
    Rasmussen PB; Staller P
    Epigenomics; 2014 Jun; 6(3):277-86. PubMed ID: 25111482
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The emerging role of KDM5A in human cancer.
    Yang GJ; Zhu MH; Lu XJ; Liu YJ; Lu JF; Leung CH; Ma DL; Chen J
    J Hematol Oncol; 2021 Feb; 14(1):30. PubMed ID: 33596982
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucose starvation impairs DNA repair in tumour cells selectively by blocking histone acetylation.
    Ampferl R; Rodemann HP; Mayer C; Höfling TTA; Dittmann K
    Radiother Oncol; 2018 Mar; 126(3):465-470. PubMed ID: 29100699
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Increased progesterone receptor A expression in labouring human myometrium is associated with decreased promoter occupancy by the histone demethylase JARID1A.
    Chai SY; Smith R; Fitter JT; Mitchell C; Pan X; Ilicic M; Maiti K; Zakar T; Madsen G
    Mol Hum Reprod; 2014 May; 20(5):442-53. PubMed ID: 24442343
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Class I histone deacetylase inhibitors inhibit the retention of BRCA1 and 53BP1 at the site of DNA damage.
    Fukuda T; Wu W; Okada M; Maeda I; Kojima Y; Hayami R; Miyoshi Y; Tsugawa K; Ohta T
    Cancer Sci; 2015 Aug; 106(8):1050-6. PubMed ID: 26053117
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The histone demethylase JARID1A regulates progesterone receptor expression.
    Stratmann A; Haendler B
    FEBS J; 2011 May; 278(9):1458-69. PubMed ID: 21348942
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks.
    Murr R; Loizou JI; Yang YG; Cuenin C; Li H; Wang ZQ; Herceg Z
    Nat Cell Biol; 2006 Jan; 8(1):91-9. PubMed ID: 16341205
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MCL-1 Depletion Impairs DNA Double-Strand Break Repair and Reinitiation of Stalled DNA Replication Forks.
    Mattoo AR; Pandita RK; Chakraborty S; Charaka V; Mujoo K; Hunt CR; Pandita TK
    Mol Cell Biol; 2017 Feb; 37(3):. PubMed ID: 27821478
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.