These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 27255383)

  • 1. Histone Deacetylase Inhibitors Prolong Cardiac Repolarization through Transcriptional Mechanisms.
    Spence S; Deurinck M; Ju H; Traebert M; McLean L; Marlowe J; Emotte C; Tritto E; Tseng M; Shultz M; Friedrichs GS
    Toxicol Sci; 2016 Sep; 153(1):39-54. PubMed ID: 27255383
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of Histone Deacetylases Induces K+ Channel Remodeling and Action Potential Prolongation in HL-1 Atrial Cardiomyocytes.
    Lugenbiel P; Govorov K; Rahm AK; Wieder T; Gramlich D; Syren P; Weiberg N; Seyler C; Katus HA; Thomas D
    Cell Physiol Biochem; 2018; 49(1):65-77. PubMed ID: 30134221
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional and Transcriptional Characterization of Histone Deacetylase Inhibitor-Mediated Cardiac Adverse Effects in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
    Kopljar I; Gallacher DJ; De Bondt A; Cougnaud L; Vlaminckx E; Van den Wyngaert I; Lu HR
    Stem Cells Transl Med; 2016 May; 5(5):602-12. PubMed ID: 27034410
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors.
    Shultz MD; Cao X; Chen CH; Cho YS; Davis NR; Eckman J; Fan J; Fekete A; Firestone B; Flynn J; Green J; Growney JD; Holmqvist M; Hsu M; Jansson D; Jiang L; Kwon P; Liu G; Lombardo F; Lu Q; Majumdar D; Meta C; Perez L; Pu M; Ramsey T; Remiszewski S; Skolnik S; Traebert M; Urban L; Uttamsingh V; Wang P; Whitebread S; Whitehead L; Yan-Neale Y; Yao YM; Zhou L; Atadja P
    J Med Chem; 2011 Jul; 54(13):4752-72. PubMed ID: 21650221
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human embryonic stem cell derived cardiac myocytes detect hERG-mediated repolarization effects, but not Nav1.5 induced depolarization delay.
    Qu Y; Gao B; Fang M; Vargas HM
    J Pharmacol Toxicol Methods; 2013; 68(1):74-81. PubMed ID: 23518063
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HDAC inhibition attenuates cardiac hypertrophy by acetylation and deacetylation of target genes.
    Ooi JY; Tuano NK; Rafehi H; Gao XM; Ziemann M; Du XJ; El-Osta A
    Epigenetics; 2015; 10(5):418-30. PubMed ID: 25941940
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BeKm-1, a peptide inhibitor of human ether-a-go-go-related gene potassium currents, prolongs QTc intervals in isolated rabbit heart.
    Qu Y; Fang M; Gao B; Chui RW; Vargas HM
    J Pharmacol Exp Ther; 2011 Apr; 337(1):2-8. PubMed ID: 21205913
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cardiac glycosides as novel inhibitors of human ether-a-go-go-related gene channel trafficking.
    Wang L; Wible BA; Wan X; Ficker E
    J Pharmacol Exp Ther; 2007 Feb; 320(2):525-34. PubMed ID: 17095614
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Utility of hERG assays as surrogate markers of delayed cardiac repolarization and QT safety.
    Gintant GA; Su Z; Martin RL; Cox BF
    Toxicol Pathol; 2006; 34(1):81-90. PubMed ID: 16507548
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanisms of HDAC inhibitor-induced thrombocytopenia.
    Matsuoka H; Unami A; Fujimura T; Noto T; Takata Y; Yoshizawa K; Mori H; Aramori I; Mutoh S
    Eur J Pharmacol; 2007 Oct; 571(2-3):88-96. PubMed ID: 17628529
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Estradiol regulates human QT-interval: acceleration of cardiac repolarization by enhanced KCNH2 membrane trafficking.
    Anneken L; Baumann S; Vigneault P; Biliczki P; Friedrich C; Xiao L; Girmatsion Z; Takac I; Brandes RP; Kissler S; Wiegratz I; Zumhagen S; Stallmeyer B; Hohnloser SH; Klingenheben T; Schulze-Bahr E; Nattel S; Ehrlich JR
    Eur Heart J; 2016 Feb; 37(7):640-50. PubMed ID: 26271031
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Histone Deacetylase Inhibitors as Anticancer Drugs.
    Eckschlager T; Plch J; Stiborova M; Hrabeta J
    Int J Mol Sci; 2017 Jul; 18(7):. PubMed ID: 28671573
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HIV protease inhibitors induced prolongation of the QT Interval: electrophysiology and clinical implications.
    Singh M; Arora R; Jawad E
    Am J Ther; 2010; 17(6):e193-201. PubMed ID: 19636247
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Ventricular arrhythmias. A potential risk associated with the use of non-cardiovascular drugs prolonging the QT interval].
    Calderone V; Cavero I
    Minerva Med; 2002 Jun; 93(3):181-97. PubMed ID: 12094149
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure.
    Freundt JK; Frommeyer G; Spieker T; Wötzel F; Grotthoff JS; Stypmann J; Hempel G; Schäfers M; Jacobs AH; Eckardt L; Lange PS
    BMC Pharmacol Toxicol; 2019 Mar; 20(1):16. PubMed ID: 30841920
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms of arsenic-induced prolongation of cardiac repolarization.
    Ficker E; Kuryshev YA; Dennis AT; Obejero-Paz C; Wang L; Hawryluk P; Wible BA; Brown AM
    Mol Pharmacol; 2004 Jul; 66(1):33-44. PubMed ID: 15213294
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Predicting drug-induced QT prolongation and torsades de pointes: a review of preclinical endpoint measures.
    Townsend C; Brown BS
    Curr Protoc Pharmacol; 2013 Jun; Chapter 10():Unit 10.16. PubMed ID: 23744708
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined histone deacetylase inhibition and tamoxifen induces apoptosis in tamoxifen-resistant breast cancer models, by reversing Bcl-2 overexpression.
    Raha P; Thomas S; Thurn KT; Park J; Munster PN
    Breast Cancer Res; 2015 Feb; 17(1):26. PubMed ID: 25848915
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New in vitro model for proarrhythmia safety screening: IKs inhibition potentiates the QTc prolonging effect of IKr inhibitors in isolated guinea pig hearts.
    Kui P; Orosz S; Takács H; Sarusi A; Csík N; Rárosi F; Csekő C; Varró A; Papp JG; Forster T; Farkas AS; Farkas A
    J Pharmacol Toxicol Methods; 2016; 80():26-34. PubMed ID: 27063345
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
    Davie C; Pierre-Valentin J; Pollard C; Standen N; Mitcheson J; Alexander P; Thong B
    J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.