These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 27258262)

  • 1. Identification of Protein-Excipient Interaction Hotspots Using Computational Approaches.
    Barata TS; Zhang C; Dalby PA; Brocchini S; Zloh M
    Int J Mol Sci; 2016 Jun; 17(6):. PubMed ID: 27258262
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Computational Characterization of Antibody-Excipient Interactions for Rational Excipient Selection Using the Site Identification by Ligand Competitive Saturation-Biologics Approach.
    Jo S; Xu A; Curtis JE; Somani S; MacKerell AD
    Mol Pharm; 2020 Nov; 17(11):4323-4333. PubMed ID: 32965126
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of a fast screening method for selecting excipients in formulations using MD simulations, NMR and microscale thermophoresis.
    Indrakumar S; Zalar M; Tschammer N; Pohl C; Nørgaard A; Streicher W; Harris P; Golovanov AP; Peters GHJ
    Eur J Pharm Biopharm; 2021 Jan; 158():11-20. PubMed ID: 33137420
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Binding of excipients is a poor predictor for aggregation kinetics of biopharmaceutical proteins.
    Zalar M; Svilenov HL; Golovanov AP
    Eur J Pharm Biopharm; 2020 Jun; 151():127-136. PubMed ID: 32283214
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bilateral Effects of Excipients on Protein Stability: Preferential Interaction Type of Excipient and Surface Aromatic Hydrophobicity of Protein.
    Wen L; Zheng X; Wang X; Lan H; Yin Z
    Pharm Res; 2017 Jul; 34(7):1378-1390. PubMed ID: 28401430
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HDX and In Silico Docking Reveal that Excipients Stabilize G-CSF via a Combination of Preferential Exclusion and Specific Hotspot Interactions.
    Wood VE; Groves K; Cryar A; Quaglia M; Matejtschuk P; Dalby PA
    Mol Pharm; 2020 Dec; 17(12):4637-4651. PubMed ID: 33112626
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Trehalose Monooleate: A Potential Antiaggregation Agent for Stabilization of Proteins.
    Kale SS; Akamanchi KG
    Mol Pharm; 2016 Dec; 13(12):4082-4093. PubMed ID: 27726389
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The surface characterisation and comparison of two potential sub-micron, sugar bulking excipients for use in low-dose, suspension formulations in metered dose inhalers.
    James J; Crean B; Davies M; Toon R; Jinks P; Roberts CJ
    Int J Pharm; 2008 Sep; 361(1-2):209-21. PubMed ID: 18577435
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Simplified choice of suitable excipients within biologics formulation design using protein-protein interaction- and water activity-maps.
    Stolzke T; Brandenbusch C
    Eur J Pharm Biopharm; 2022 Jul; 176():153-167. PubMed ID: 35643368
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Toward Biotherapeutics Formulation Composition Engineering using Site-Identification by Ligand Competitive Saturation (SILCS).
    Somani S; Jo S; Thirumangalathu R; Rodrigues D; Tanenbaum LM; Amin K; MacKerell AD; Thakkar SV
    J Pharm Sci; 2021 Mar; 110(3):1103-1110. PubMed ID: 33137372
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein-excipient interactions: mechanisms and biophysical characterization applied to protein formulation development.
    Kamerzell TJ; Esfandiary R; Joshi SB; Middaugh CR; Volkin DB
    Adv Drug Deliv Rev; 2011 Oct; 63(13):1118-59. PubMed ID: 21855584
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Towards an improved understanding of drug excipient interactions to enable rapid optimization of nanosuspension formulations.
    Ferrar JA; Sellers BD; Chan C; Leung DH
    Int J Pharm; 2020 Mar; 578():119094. PubMed ID: 32006625
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of aggregation breakers for bevacizumab (Avastin®) self-association through similarity searching and interaction studies.
    Westermaier Y; Veurink M; Riis-Johannessen T; Guinchard S; Gurny R; Scapozza L
    Eur J Pharm Biopharm; 2013 Nov; 85(3 Pt A):773-80. PubMed ID: 23665445
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Studies of bicalutamide-excipients interaction by combination of molecular docking and molecular dynamics simulation.
    Li C; Wang JX; Le Y; Chen JF
    Mol Pharm; 2013 Jun; 10(6):2362-9. PubMed ID: 23646858
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Control of Globular Protein Thermal Stability in Aqueous Formulations by the Positively Charged Amino Acid Excipients.
    Platts L; Darby SJ; Falconer RJ
    J Pharm Sci; 2016 Dec; 105(12):3532-3536. PubMed ID: 27776770
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assessing the efficiency of polymeric excipients by atomistic molecular dynamics simulations.
    Jha PK; Larson RG
    Mol Pharm; 2014 May; 11(5):1676-86. PubMed ID: 24708235
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction of a Macrocycle with an Aggregation-Prone Region of a Monoclonal Antibody.
    Martinez Morales M; Zalar M; Sonzini S; Golovanov AP; van der Walle CF; Derrick JP
    Mol Pharm; 2019 Jul; 16(7):3100-3108. PubMed ID: 31088082
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interactions of formulation excipients with proteins in solution and in the dried state.
    Ohtake S; Kita Y; Arakawa T
    Adv Drug Deliv Rev; 2011 Oct; 63(13):1053-73. PubMed ID: 21756953
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rational approach for design and evaluation of anti-aggregation agents for protein stabilization: A case study of trehalose phenylalaninate.
    Kale SS; Akamanchi KG
    Int J Pharm; 2017 May; 524(1-2):215-225. PubMed ID: 28365391
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Excipient-assisted vinpocetine nanoparticles: experiments and molecular dynamic simulations.
    Li CX; Wang HB; Oppong D; Wang JX; Chen JF; Le Y
    Mol Pharm; 2014 Nov; 11(11):4023-35. PubMed ID: 25244002
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.