BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

530 related articles for article (PubMed ID: 27258413)

  • 1. A Novel Splice-Acceptor Site Mutation in GRN (c.709-2 A>T) Causes Frontotemporal Dementia Spectrum in a Large Family from Southern Italy.
    Sassi C; Capozzo R; Gibbs R; Crews C; Zecca C; Arcuti S; Copetti M; Barulli MR; Brescia V; Singleton AB; Logroscino G
    J Alzheimers Dis; 2016 May; 53(2):475-85. PubMed ID: 27258413
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers.
    Alquézar C; de la Encarnación A; Moreno F; López de Munain A; Martín-Requero Á
    J Psychiatry Neurosci; 2016 Jun; 41(4):225-39. PubMed ID: 26624524
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Peripheral GRN mRNA and Serum Progranulin Levels as a Potential Indicator for Both the Presence of Splice Site Mutations and Individuals at Risk for Frontotemporal Dementia.
    Guven G; Bilgic B; Tufekcioglu Z; Erginel Unaltuna N; Hanagasi H; Gurvit H; Singleton A; Hardy J; Emre M; Gulec C; Bras J; Guerreiro R; Lohmann E
    J Alzheimers Dis; 2019; 67(1):159-167. PubMed ID: 30475763
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members.
    Finch N; Baker M; Crook R; Swanson K; Kuntz K; Surtees R; Bisceglio G; Rovelet-Lecrux A; Boeve B; Petersen RC; Dickson DW; Younkin SG; Deramecourt V; Crook J; Graff-Radford NR; Rademakers R
    Brain; 2009 Mar; 132(Pt 3):583-91. PubMed ID: 19158106
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration.
    Yu CE; Bird TD; Bekris LM; Montine TJ; Leverenz JB; Steinbart E; Galloway NM; Feldman H; Woltjer R; Miller CA; Wood EM; Grossman M; McCluskey L; Clark CM; Neumann M; Danek A; Galasko DR; Arnold SE; Chen-Plotkin A; Karydas A; Miller BL; Trojanowski JQ; Lee VM; Schellenberg GD; Van Deerlin VM
    Arch Neurol; 2010 Feb; 67(2):161-70. PubMed ID: 20142524
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cerebrospinal Fluid Progranulin, but Not Serum Progranulin, Is Reduced in GRN-Negative Frontotemporal Dementia.
    Wilke C; Gillardon F; Deuschle C; Hobert MA; Jansen IE; Metzger FG; Heutink P; Gasser T; Maetzler W; Blauwendraat C; Synofzik M
    Neurodegener Dis; 2017; 17(2-3):83-88. PubMed ID: 27760429
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Serum progranulin levels in patients with frontotemporal lobar degeneration and Alzheimer's disease: detection of GRN mutations in a Spanish cohort.
    Antonell A; Gil S; Sánchez-Valle R; Balasa M; Bosch B; Prat MC; Chiollaz AC; Fernández M; Yagüe J; Molinuevo JL; Lladó A
    J Alzheimers Dis; 2012; 31(3):581-91. PubMed ID: 22647257
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A mutation in the 5'-UTR of GRN gene associated with frontotemporal lobar degeneration: phenotypic variability and possible pathogenetic mechanisms.
    Puoti G; Lerza MC; Ferretti MG; Bugiani O; Tagliavini F; Rossi G
    J Alzheimers Dis; 2014; 42(3):939-47. PubMed ID: 25024321
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia.
    Mukherjee O; Wang J; Gitcho M; Chakraverty S; Taylor-Reinwald L; Shears S; Kauwe JS; Norton J; Levitch D; Bigio EH; Hatanpaa KJ; White CL; Morris JC; Cairns NJ; Goate A
    Hum Mutat; 2008 Apr; 29(4):512-21. PubMed ID: 18183624
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rare exonic variant affects GRN splicing and contributes to frontotemporal lobar degeneration.
    Wauters E; Gossye H; Frydas A; Sieben A; Van Broeckhoven C
    Neurobiol Aging; 2023 Oct; 130():61-69. PubMed ID: 37459659
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia.
    Holler CJ; Taylor G; McEachin ZT; Deng Q; Watkins WJ; Hudson K; Easley CA; Hu WT; Hales CM; Rossoll W; Bassell GJ; Kukar T
    Mol Neurodegener; 2016 Jun; 11(1):46. PubMed ID: 27341800
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A systematic review of progranulin concentrations in biofluids in over 7,000 people-assessing the pathogenicity of GRN mutations and other influencing factors.
    Swift IJ; Rademakers R; Finch N; Baker M; Ghidoni R; Benussi L; Binetti G; Rossi G; Synofzik M; Wilke C; Mengel D; Graff C; Takada LT; Sánchez-Valle R; Antonell A; Galimberti D; Fenoglio C; Serpente M; Arcaro M; Schreiber S; Vielhaber S; Arndt P; Santana I; Almeida MR; Moreno F; Barandiaran M; Gabilondo A; Stubert J; Gómez-Tortosa E; Agüero P; Sainz MJ; Gohda T; Murakoshi M; Kamei N; Kittel-Schneider S; Reif A; Weigl J; Jian J; Liu C; Serrero G; Greither T; Theil G; Lohmann E; Gazzina S; Bagnoli S; Coppola G; Bruni A; Quante M; Kiess W; Hiemisch A; Jurkutat A; Block MS; Carlson AM; Bråthen G; Sando SB; Grøntvedt GR; Lauridsen C; Heslegrave A; Heller C; Abel E; Gómez-Núñez A; Puey R; Arighi A; Rotondo E; Jiskoot LC; Meeter LHH; Durães J; Lima M; Tábuas-Pereira M; Lemos J; Boeve B; Petersen RC; Dickson DW; Graff-Radford NR; LeBer I; Sellami L; Lamari F; Clot F; Borroni B; Cantoni V; Rivolta J; Lleó A; Fortea J; Alcolea D; Illán-Gala I; Andres-Cerezo L; Van Damme P; Clarimon J; Steinacker P; Feneberg E; Otto M; van der Ende EL; van Swieten JC; Seelaar H; Zetterberg H; Sogorb-Esteve A; Rohrer JD
    Alzheimers Res Ther; 2024 Mar; 16(1):66. PubMed ID: 38539243
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations.
    Huang M; Modeste E; Dammer E; Merino P; Taylor G; Duong DM; Deng Q; Holler CJ; Gearing M; Dickson D; Seyfried NT; Kukar T
    Acta Neuropathol Commun; 2020 Oct; 8(1):163. PubMed ID: 33028409
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic Features of MAPT, GRN, C9orf72 and CHCHD10 Gene Mutations in Chinese Patients with Frontotemporal Dementia.
    Che XQ; Zhao QH; Huang Y; Li X; Ren RJ; Chen SD; Wang G; Guo QH
    Curr Alzheimer Res; 2017; 14(10):1102-1108. PubMed ID: 28462717
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Heterogeneity within a large kindred with frontotemporal dementia: a novel progranulin mutation.
    Bruni AC; Momeni P; Bernardi L; Tomaino C; Frangipane F; Elder J; Kawarai T; Sato C; Pradella S; Wakutani Y; Anfossi M; Gallo M; Geracitano S; Costanzo A; Smirne N; Curcio SA; Mirabelli M; Puccio G; Colao R; Maletta RG; Kertesz A; St George-Hyslop P; Hardy J; Rogaeva E
    Neurology; 2007 Jul; 69(2):140-7. PubMed ID: 17620546
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.
    Ward ME; Chen R; Huang HY; Ludwig C; Telpoukhovskaia M; Taubes A; Boudin H; Minami SS; Reichert M; Albrecht P; Gelfand JM; Cruz-Herranz A; Cordano C; Alavi MV; Leslie S; Seeley WW; Miller BL; Bigio E; Mesulam MM; Bogyo MS; Mackenzie IR; Staropoli JF; Cotman SL; Huang EJ; Gan L; Green AJ
    Sci Transl Med; 2017 Apr; 9(385):. PubMed ID: 28404863
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Novel Loss-of-Function GRN Mutation p.(Tyr229*): Clinical and Neuropathological Features.
    Kuuluvainen L; Pöyhönen M; Pasanen P; Siitonen M; Rummukainen J; Tienari PJ; Paetau A; Myllykangas L
    J Alzheimers Dis; 2017; 55(3):1167-1174. PubMed ID: 27767988
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Homozygous GRN mutations: new phenotypes and new insights into pathological and molecular mechanisms.
    Huin V; Barbier M; Bottani A; Lobrinus JA; Clot F; Lamari F; Chat L; Rucheton B; Fluchère F; Auvin S; Myers P; Gelot A; Camuzat A; Caillaud C; Jornéa L; Forlani S; Saracino D; Duyckaerts C; Brice A; Durr A; Le Ber I
    Brain; 2020 Jan; 143(1):303-319. PubMed ID: 31855245
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Progranulin peripheral levels as a screening tool for the identification of subjects with progranulin mutations in a Portuguese cohort.
    Almeida MR; Baldeiras I; Ribeiro MH; Santiago B; Machado C; Massano J; Guimarães J; Resende Oliveira C; Santana I
    Neurodegener Dis; 2014; 13(4):214-23. PubMed ID: 24022032
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Association of the variant Cys139Arg at GRN gene to the clinical spectrum of frontotemporal lobar degeneration.
    Piaceri I; Pradella S; Cupidi C; Nannucci S; Polito C; Bagnoli S; Tedde A; Smirne N; Anfossi M; Gallo M; Bernardi L; Colao R; Maletta R; Bruni AC; Sorbi S; Nacmias B
    J Alzheimers Dis; 2014; 40(3):679-85. PubMed ID: 24503614
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.