These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

317 related articles for article (PubMed ID: 27259151)

  • 1. Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
    Brown NG; VanderLinden R; Watson ER; Weissmann F; Ordureau A; Wu KP; Zhang W; Yu S; Mercredi PY; Harrison JS; Davidson IF; Qiao R; Lu Y; Dube P; Brunner MR; Grace CRR; Miller DJ; Haselbach D; Jarvis MA; Yamaguchi M; Yanishevski D; Petzold G; Sidhu SS; Kuhlman B; Kirschner MW; Harper JW; Peters JM; Stark H; Schulman BA
    Cell; 2016 Jun; 165(6):1440-1453. PubMed ID: 27259151
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex.
    Brown NG; VanderLinden R; Watson ER; Qiao R; Grace CR; Yamaguchi M; Weissmann F; Frye JJ; Dube P; Ei Cho S; Actis ML; Rodrigues P; Fujii N; Peters JM; Stark H; Schulman BA
    Proc Natl Acad Sci U S A; 2015 Apr; 112(17):5272-9. PubMed ID: 25825779
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming.
    Martinez-Chacin RC; Bodrug T; Bolhuis DL; Kedziora KM; Bonacci T; Ordureau A; Gibbs ME; Weissmann F; Qiao R; Grant GD; Cook JG; Peters JM; Wade Harper J; Emanuele MJ; Brown NG
    Nat Struct Mol Biol; 2020 Jun; 27(6):550-560. PubMed ID: 32393902
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
    Yamaguchi M; VanderLinden R; Weissmann F; Qiao R; Dube P; Brown NG; Haselbach D; Zhang W; Sidhu SS; Peters JM; Stark H; Schulman BA
    Mol Cell; 2016 Aug; 63(4):593-607. PubMed ID: 27522463
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site.
    Watson ER; Grace CRR; Zhang W; Miller DJ; Davidson IF; Prabu JR; Yu S; Bolhuis DL; Kulko ET; Vollrath R; Haselbach D; Stark H; Peters JM; Brown NG; Sidhu SS; Schulman BA
    Proc Natl Acad Sci U S A; 2019 Aug; 116(35):17280-17289. PubMed ID: 31350353
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Atomic structure of the APC/C and its mechanism of protein ubiquitination.
    Chang L; Zhang Z; Yang J; McLaughlin SH; Barford D
    Nature; 2015 Jun; 522(7557):450-454. PubMed ID: 26083744
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
    Bodrug T; Welsh KA; Bolhuis DL; PaulŠ°konis E; Martinez-Chacin RC; Liu B; Pinkin N; Bonacci T; Cui L; Xu P; Roscow O; Amann SJ; Grishkovskaya I; Emanuele MJ; Harrison JS; Steimel JP; Hahn KM; Zhang W; Zhong ED; Haselbach D; Brown NG
    Nat Struct Mol Biol; 2023 Nov; 30(11):1663-1674. PubMed ID: 37735619
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly.
    Brown NG; Watson ER; Weissmann F; Jarvis MA; VanderLinden R; Grace CRR; Frye JJ; Qiao R; Dube P; Petzold G; Cho SE; Alsharif O; Bao J; Davidson IF; Zheng JJ; Nourse A; Kurinov I; Peters JM; Stark H; Schulman BA
    Mol Cell; 2014 Oct; 56(2):246-260. PubMed ID: 25306923
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex.
    Wu T; Merbl Y; Huo Y; Gallop JL; Tzur A; Kirschner MW
    Proc Natl Acad Sci U S A; 2010 Jan; 107(4):1355-60. PubMed ID: 20080579
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular basis for lysine specificity in the yeast ubiquitin-conjugating enzyme Cdc34.
    Sadowski M; Suryadinata R; Lai X; Heierhorst J; Sarcevic B
    Mol Cell Biol; 2010 May; 30(10):2316-29. PubMed ID: 20194622
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An E2 accessory domain increases affinity for the anaphase-promoting complex and ensures E2 competition.
    Girard JR; Tenthorey JL; Morgan DO
    J Biol Chem; 2015 Oct; 290(40):24614-25. PubMed ID: 26306044
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation.
    Craney A; Kelly A; Jia L; Fedrigo I; Yu H; Rape M
    Proc Natl Acad Sci U S A; 2016 Feb; 113(6):1540-5. PubMed ID: 26811472
    [TBL] [Abstract][Full Text] [Related]  

  • 13. WD40 domain of Apc1 is critical for the coactivator-induced allosteric transition that stimulates APC/C catalytic activity.
    Li Q; Chang L; Aibara S; Yang J; Zhang Z; Barford D
    Proc Natl Acad Sci U S A; 2016 Sep; 113(38):10547-52. PubMed ID: 27601667
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular architecture and mechanism of the anaphase-promoting complex.
    Chang LF; Zhang Z; Yang J; McLaughlin SH; Barford D
    Nature; 2014 Sep; 513(7518):388-393. PubMed ID: 25043029
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of the APC/C ubiquitin ligase by enhanced E2 efficiency.
    Van Voorhis VA; Morgan DO
    Curr Biol; 2014 Jul; 24(13):1556-62. PubMed ID: 24930963
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The essential Ubc4/Ubc5 function in yeast is HECT E3-dependent, and RING E3-dependent pathways require only monoubiquitin transfer by Ubc4.
    Stoll KE; Brzovic PS; Davis TN; Klevit RE
    J Biol Chem; 2011 Apr; 286(17):15165-70. PubMed ID: 21357418
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division.
    Watson ER; Brown NG; Peters JM; Stark H; Schulman BA
    Trends Cell Biol; 2019 Feb; 29(2):117-134. PubMed ID: 30482618
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of a physiological E2 module for the human anaphase-promoting complex.
    Williamson A; Wickliffe KE; Mellone BG; Song L; Karpen GH; Rape M
    Proc Natl Acad Sci U S A; 2009 Oct; 106(43):18213-8. PubMed ID: 19822757
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional conservation and divergence of the helix-turn-helix motif of E2 ubiquitin-conjugating enzymes.
    Welsh KA; Bolhuis DL; Nederstigt AE; Boyer J; Temple BRS; Bonacci T; Gu L; Ordureau A; Harper JW; Steimel JP; Zhang Q; Emanuele MJ; Harrison JS; Brown NG
    EMBO J; 2022 Feb; 41(3):e108823. PubMed ID: 34942047
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S.
    Liess AKL; Kucerova A; Schweimer K; Schlesinger D; Dybkov O; Urlaub H; Mansfeld J; Lorenz S
    Sci Signal; 2020 Oct; 13(654):. PubMed ID: 33082289
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.