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5. Targeting the IGF1R/PI3K/AKT Pathway Sensitizes Ewing Sarcoma to BET Bromodomain Inhibitors. Loganathan SN; Tang N; Holler AE; Wang N; Wang J Mol Cancer Ther; 2019 May; 18(5):929-936. PubMed ID: 30926641 [TBL] [Abstract][Full Text] [Related]
6. PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1. Giorgi C; Boro A; Rechfeld F; Lopez-Garcia LA; Gierisch ME; Schäfer BW; Niggli FK Oncotarget; 2015 Oct; 6(30):28895-910. PubMed ID: 26336820 [TBL] [Abstract][Full Text] [Related]
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10. Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening. Grohar PJ; Woldemichael GM; Griffin LB; Mendoza A; Chen QR; Yeung C; Currier DG; Davis S; Khanna C; Khan J; McMahon JB; Helman LJ J Natl Cancer Inst; 2011 Jun; 103(12):962-78. PubMed ID: 21653923 [TBL] [Abstract][Full Text] [Related]
11. Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner. Harlow ML; Chasse MH; Boguslawski EA; Sorensen KM; Gedminas JM; Kitchen-Goosen SM; Rothbart SB; Taslim C; Lessnick SL; Peck AS; Madaj ZB; Bowman MJ; Grohar PJ Clin Cancer Res; 2019 Jun; 25(11):3417-3429. PubMed ID: 30723142 [TBL] [Abstract][Full Text] [Related]
12. Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma. Boro A; Prêtre K; Rechfeld F; Thalhammer V; Oesch S; Wachtel M; Schäfer BW; Niggli FK Int J Cancer; 2012 Nov; 131(9):2153-64. PubMed ID: 22323082 [TBL] [Abstract][Full Text] [Related]
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14. Pharmacokinetic modeling optimizes inhibition of the 'undruggable' EWS-FLI1 transcription factor in Ewing Sarcoma. Hong SH; Youbi SE; Hong SP; Kallakury B; Monroe P; Erkizan HV; Barber-Rotenberg JS; Houghton P; Üren A; Toretsky JA Oncotarget; 2014 Jan; 5(2):338-50. PubMed ID: 24481407 [TBL] [Abstract][Full Text] [Related]
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17. CRM1 Inhibition Promotes Cytotoxicity in Ewing Sarcoma Cells by Repressing EWS-FLI1-Dependent IGF-1 Signaling. Sun H; Lin DC; Cao Q; Guo X; Marijon H; Zhao Z; Gery S; Xu L; Yang H; Pang B; Lee VK; Lim HJ; Doan N; Said JW; Chu P; Mayakonda A; Thomas T; Forscher C; Baloglu E; Shacham S; Rajalingam R; Koeffler HP Cancer Res; 2016 May; 76(9):2687-97. PubMed ID: 26956669 [TBL] [Abstract][Full Text] [Related]
18. High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability. He T; Surdez D; Rantala JK; Haapa-Paananen S; Ban J; Kauer M; Tomazou E; Fey V; Alonso J; Kovar H; Delattre O; Iljin K Gene; 2017 Jan; 596():137-146. PubMed ID: 27760381 [TBL] [Abstract][Full Text] [Related]
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