BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

273 related articles for article (PubMed ID: 27264869)

  • 1. Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.
    Riscal R; Schrepfer E; Arena G; Cissé MY; Bellvert F; Heuillet M; Rambow F; Bonneil E; Sabourdy F; Vincent C; Ait-Arsa I; Levade T; Thibaut P; Marine JC; Portais JC; Sarry JE; Le Cam L; Linares LK
    Mol Cell; 2016 Jun; 62(6):890-902. PubMed ID: 27264869
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53.
    Arena G; Cissé MY; Pyrdziak S; Chatre L; Riscal R; Fuentes M; Arnold JJ; Kastner M; Gayte L; Bertrand-Gaday C; Nay K; Angebault-Prouteau C; Murray K; Chabi B; Koechlin-Ramonatxo C; Orsetti B; Vincent C; Casas F; Marine JC; Etienne-Manneville S; Bernex F; Lombès A; Cameron CE; Dubouchaud H; Ricchetti M; Linares LK; Le Cam L
    Mol Cell; 2018 Feb; 69(4):594-609.e8. PubMed ID: 29452639
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer.
    Wu DW; Lee MC; Wang J; Chen CY; Cheng YW; Lee H
    Oncogene; 2014 Mar; 33(12):1515-26. PubMed ID: 23584477
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mouse double minute 2 associates with chromatin in the presence of p53 and is released to facilitate activation of transcription.
    White DE; Talbott KE; Arva NC; Bargonetti J
    Cancer Res; 2006 Apr; 66(7):3463-70. PubMed ID: 16585169
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
    Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
    Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of expression of the p21
    Mantsou A; Koutsogiannouli E; Haitoglou C; Papavassiliou AG; Papanikolaou NA
    Biochem Cell Biol; 2016 Dec; 94(6):560-568. PubMed ID: 27792410
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53.
    Wienken M; Dickmanns A; Nemajerova A; Kramer D; Najafova Z; Weiss M; Karpiuk O; Kassem M; Zhang Y; Lozano G; Johnsen SA; Moll UM; Zhang X; Dobbelstein M
    Mol Cell; 2016 Jan; 61(1):68-83. PubMed ID: 26748827
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p38 MAPK-induced MDM2 degradation confers paclitaxel resistance through p53-mediated regulation of EGFR in human lung cancer cells.
    Park SH; Seong MA; Lee HY
    Oncotarget; 2016 Feb; 7(7):8184-99. PubMed ID: 26799187
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MDM2 overexpression deregulates the transcriptional control of RB/E2F leading to DNA methyltransferase 3A overexpression in lung cancer.
    Tang YA; Lin RK; Tsai YT; Hsu HS; Yang YC; Chen CY; Wang YC
    Clin Cancer Res; 2012 Aug; 18(16):4325-33. PubMed ID: 22733537
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent apoptotic pathway in human non-small cell lung cancer cells.
    Deng WG; Kawashima H; Wu G; Jayachandran G; Xu K; Minna JD; Roth JA; Ji L
    Cancer Res; 2007 Jan; 67(2):709-17. PubMed ID: 17234782
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner.
    Liu X; Liu Y; Liu Z; Lin C; Meng F; Xu L; Zhang X; Zhang C; Zhang P; Gong S; Wu N; Ren Z; Song J; Zhang Y
    Mol Cancer; 2021 Sep; 20(1):114. PubMed ID: 34496888
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Associations of MDM2 SNP309, transcriptional activity, mRNA expression, and survival in stage I non-small-cell lung cancer patients with wild-type p53 tumors.
    Chien WP; Wong RH; Cheng YW; Chen CY; Lee H
    Ann Surg Oncol; 2010 Apr; 17(4):1194-202. PubMed ID: 19941079
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein phosphatase 1 nuclear targeting subunit is a hypoxia inducible gene: its role in post-translational modification of p53 and MDM2.
    Lee SJ; Lim CJ; Min JK; Lee JK; Kim YM; Lee JY; Won MH; Kwon YG
    Cell Death Differ; 2007 Jun; 14(6):1106-16. PubMed ID: 17318220
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation.
    Qin JJ; Wang W; Voruganti S; Wang H; Zhang WD; Zhang R
    Oncotarget; 2015 Feb; 6(5):2623-40. PubMed ID: 25739118
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cooperation of Musashi-2, Numb, MDM2, and P53 in drug resistance and malignant biology of pancreatic cancer.
    Sheng W; Dong M; Chen C; Wang Z; Li Y; Wang K; Li Y; Zhou J
    FASEB J; 2017 Jun; 31(6):2429-2438. PubMed ID: 28223335
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Roles for negative cell regulator 14-3-3sigma in control of MDM2 activities.
    Yang HY; Wen YY; Lin YI; Pham L; Su CH; Yang H; Chen J; Lee MH
    Oncogene; 2007 Nov; 26(52):7355-62. PubMed ID: 17546054
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations.
    Di Stefano V; Mattiussi M; Sacchi A; D'Orazi G
    FEBS Lett; 2005 Oct; 579(25):5473-80. PubMed ID: 16212962
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.
    Okamoto K; Kashima K; Pereg Y; Ishida M; Yamazaki S; Nota A; Teunisse A; Migliorini D; Kitabayashi I; Marine JC; Prives C; Shiloh Y; Jochemsen AG; Taya Y
    Mol Cell Biol; 2005 Nov; 25(21):9608-20. PubMed ID: 16227609
    [TBL] [Abstract][Full Text] [Related]  

  • 19. E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines.
    Kitagawa M; Aonuma M; Lee SH; Fukutake S; McCormick F
    Oncogene; 2008 Sep; 27(40):5303-14. PubMed ID: 18521084
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mir-660 is downregulated in lung cancer patients and its replacement inhibits lung tumorigenesis by targeting MDM2-p53 interaction.
    Fortunato O; Boeri M; Moro M; Verri C; Mensah M; Conte D; Caleca L; Roz L; Pastorino U; Sozzi G
    Cell Death Dis; 2014 Dec; 5(12):e1564. PubMed ID: 25501825
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.