These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 27266634)

  • 1. Neurofibromin is a novel regulator of Ras-induced reactive oxygen species production in mice and humans.
    Bessler WK; Hudson FZ; Zhang H; Harris V; Wang Y; Mund JA; Downing B; Ingram DA; Case J; Fulton DJ; Stansfield BK
    Free Radic Biol Med; 2016 Aug; 97():212-222. PubMed ID: 27266634
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nf1+/- monocytes/macrophages induce neointima formation via CCR2 activation.
    Bessler WK; Kim G; Hudson FZ; Mund JA; Mali R; Menon K; Kapur R; Clapp DW; Ingram DA; Stansfield BK
    Hum Mol Genet; 2016 Mar; 25(6):1129-39. PubMed ID: 26740548
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ras-Mek-Erk signaling regulates Nf1 heterozygous neointima formation.
    Stansfield BK; Bessler WK; Mali R; Mund JA; Downing BD; Kapur R; Ingram DA
    Am J Pathol; 2014 Jan; 184(1):79-85. PubMed ID: 24211110
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heterozygous inactivation of the Nf1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway.
    Stansfield BK; Bessler WK; Mali R; Mund JA; Downing B; Li F; Sarchet KN; DiStasi MR; Conway SJ; Kapur R; Ingram DA
    Hum Mol Genet; 2013 Mar; 22(5):977-88. PubMed ID: 23197650
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of GTPase activating protein neurofibromin stimulates paracrine cell communication via macropinocytosis.
    Ghoshal P; Singla B; Lin H; Cherian-Shaw M; Tritz R; Padgett CA; Hudson F; Zhang H; Stansfield BK; Csányi G
    Redox Biol; 2019 Oct; 27():101224. PubMed ID: 31201114
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MEK inhibition exerts temporal and myeloid cell-specific effects in the pathogenesis of neurofibromatosis type 1 arteriopathy.
    Tritz R; Hudson FZ; Harris V; Ghoshal P; Singla B; Lin H; Csanyi G; Stansfield BK
    Sci Rep; 2021 Dec; 11(1):24345. PubMed ID: 34934133
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells.
    McDaniel AS; Allen JD; Park SJ; Jaffer ZM; Michels EG; Burgin SJ; Chen S; Bessler WK; Hofmann C; Ingram DA; Chernoff J; Clapp DW
    Blood; 2008 Dec; 112(12):4646-54. PubMed ID: 18768391
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro.
    Ingram DA; Hiatt K; King AJ; Fisher L; Shivakumar R; Derstine C; Wenning MJ; Diaz B; Travers JB; Hood A; Marshall M; Williams DA; Clapp DW
    J Exp Med; 2001 Jul; 194(1):57-69. PubMed ID: 11435472
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction between a Domain of the Negative Regulator of the Ras-ERK Pathway, SPRED1 Protein, and the GTPase-activating Protein-related Domain of Neurofibromin Is Implicated in Legius Syndrome and Neurofibromatosis Type 1.
    Hirata Y; Brems H; Suzuki M; Kanamori M; Okada M; Morita R; Llano-Rivas I; Ose T; Messiaen L; Legius E; Yoshimura A
    J Biol Chem; 2016 Feb; 291(7):3124-34. PubMed ID: 26635368
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans.
    Lasater EA; Li F; Bessler WK; Estes ML; Vemula S; Hingtgen CM; Dinauer MC; Kapur R; Conway SJ; Ingram DA
    J Clin Invest; 2010 Mar; 120(3):859-70. PubMed ID: 20160346
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neurofibromin is a novel regulator of RAS-induced signals in primary vascular smooth muscle cells.
    Li F; Munchhof AM; White HA; Mead LE; Krier TR; Fenoglio A; Chen S; Wu X; Cai S; Yang FC; Ingram DA
    Hum Mol Genet; 2006 Jun; 15(11):1921-30. PubMed ID: 16644864
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.
    Yang FC; Chen S; Robling AG; Yu X; Nebesio TD; Yan J; Morgan T; Li X; Yuan J; Hock J; Ingram DA; Clapp DW
    J Clin Invest; 2006 Nov; 116(11):2880-91. PubMed ID: 17053831
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stimulus-evoked release of neuropeptides is enhanced in sensory neurons from mice with a heterozygous mutation of the Nf1 gene.
    Hingtgen CM; Roy SL; Clapp DW
    Neuroscience; 2006; 137(2):637-45. PubMed ID: 16298082
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neurofibromatosis 1: closing the GAP between mice and men.
    Dasgupta B; Gutmann DH
    Curr Opin Genet Dev; 2003 Feb; 13(1):20-7. PubMed ID: 12573431
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neurofibromatosis type 1 (NF1) tumor suppressor, neurofibromin, regulates the neuronal differentiation of PC12 cells via its associating protein, CRMP-2.
    Patrakitkomjorn S; Kobayashi D; Morikawa T; Wilson MM; Tsubota N; Irie A; Ozawa T; Aoki M; Arimura N; Kaibuchi K; Saya H; Araki N
    J Biol Chem; 2008 Apr; 283(14):9399-413. PubMed ID: 18218617
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NF1 regulates a Ras-dependent vascular smooth muscle proliferative injury response.
    Xu J; Ismat FA; Wang T; Yang J; Epstein JA
    Circulation; 2007 Nov; 116(19):2148-56. PubMed ID: 17967772
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neurofibromatosis Type 1 and tumorigenesis: molecular mechanisms and therapeutic implications.
    Gottfried ON; Viskochil DH; Couldwell WT
    Neurosurg Focus; 2010 Jan; 28(1):E8. PubMed ID: 20043723
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hyperactive Ras/MAPK signaling is critical for tibial nonunion fracture in neurofibromin-deficient mice.
    Sharma R; Wu X; Rhodes SD; Chen S; He Y; Yuan J; Li J; Yang X; Li X; Jiang L; Kim ET; Stevenson DA; Viskochil D; Xu M; Yang FC
    Hum Mol Genet; 2013 Dec; 22(23):4818-28. PubMed ID: 23863460
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of the nf1 tumor suppressor gene decreases fas antigen expression in myeloid cells.
    Hiatt K; Ingram DA; Huddleston H; Spandau DF; Kapur R; Clapp DW
    Am J Pathol; 2004 Apr; 164(4):1471-9. PubMed ID: 15039234
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neurofibromin GTPase-activating protein-related domains restore normal growth in Nf1-/- cells.
    Hiatt KK; Ingram DA; Zhang Y; Bollag G; Clapp DW
    J Biol Chem; 2001 Mar; 276(10):7240-5. PubMed ID: 11080503
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.