These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

807 related articles for article (PubMed ID: 27270440)

  • 1. A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression.
    Chen H; Lorton B; Gupta V; Shechter D
    Oncogene; 2017 Jan; 36(3):373-386. PubMed ID: 27270440
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling.
    Saha K; Adhikary G; Eckert RL
    J Invest Dermatol; 2016 Jan; 136(1):214-224. PubMed ID: 26763441
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histone H2A and H4 N-terminal tails are positioned by the MEP50 WD repeat protein for efficient methylation by the PRMT5 arginine methyltransferase.
    Burgos ES; Wilczek C; Onikubo T; Bonanno JB; Jansong J; Reimer U; Shechter D
    J Biol Chem; 2015 Apr; 290(15):9674-89. PubMed ID: 25713080
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation.
    Saha K; Fisher ML; Adhikary G; Grun D; Eckert RL
    Carcinogenesis; 2017 Aug; 38(8):827-836. PubMed ID: 28854561
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Curcumin ameliorates PRMT5-MEP50 arginine methyltransferase expression by decreasing the Sp1 and NF-YA transcription factors in the A549 and MCF-7 cells.
    Chatterjee B; Ghosh K; Suresh L; Kanade SR
    Mol Cell Biochem; 2019 May; 455(1-2):73-90. PubMed ID: 30392062
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Methylosome Protein 50 and PKCδ/p38δ Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene Expression.
    Saha K; Eckert RL
    J Biol Chem; 2015 May; 290(21):13521-30. PubMed ID: 25851901
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lead induces the up-regulation of the protein arginine methyltransferase 5 possibly by its promoter demethylation.
    Ghosh K; Chatterjee B; Kanade SR
    Biochem J; 2018 Aug; 475(16):2653-2666. PubMed ID: 30054435
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond.
    Stopa N; Krebs JE; Shechter D
    Cell Mol Life Sci; 2015 Jun; 72(11):2041-59. PubMed ID: 25662273
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sulforaphane inhibits PRMT5 and MEP50 function to suppress the mesothelioma cancer cell phenotype.
    Ezeka G; Adhikary G; Kandasamy S; Friedberg JS; Eckert RL
    Mol Carcinog; 2021 Jul; 60(7):429-439. PubMed ID: 33872411
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells.
    Mongiardi MP; Savino M; Bartoli L; Beji S; Nanni S; Scagnoli F; Falchetti ML; Favia A; Farsetti A; Levi A; Nasi S; Illi B
    Sci Rep; 2015 Nov; 5():15494. PubMed ID: 26563484
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion.
    Wang M; Fuhrmann J; Thompson PR
    Biochemistry; 2014 Dec; 53(50):7884-92. PubMed ID: 25485739
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferation.
    Sheng X; Wang Z
    BMC Cancer; 2016 Aug; 16():567. PubMed ID: 27480244
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes.
    Tsutsui T; Fukasawa R; Shinmyouzu K; Nakagawa R; Tobe K; Tanaka A; Ohkuma Y
    J Biol Chem; 2013 Jul; 288(29):20955-20965. PubMed ID: 23749998
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PRMT5-dependent transcriptional repression of c-Myc target genes promotes gastric cancer progression.
    Liu M; Yao B; Gui T; Guo C; Wu X; Li J; Ma L; Deng Y; Xu P; Wang Y; Yang D; Li Q; Zeng X; Li X; Hu R; Ge J; Yu Z; Chen Y; Chen B; Ju J; Zhao Q
    Theranostics; 2020; 10(10):4437-4452. PubMed ID: 32292506
    [TBL] [Abstract][Full Text] [Related]  

  • 15. OGG1 regulates the level of symmetric dimethylation of histone H4 arginine-3 by interacting with PRMT5.
    Zhou X; Wang W; Du C; Yan F; Yang S; He K; Wang H; Zhao A
    Mol Cell Probes; 2018 Apr; 38():19-24. PubMed ID: 29409673
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein arginine methyltransferase 5 promotes lung cancer metastasis via the epigenetic regulation of miR-99 family/FGFR3 signaling.
    Jing P; Zhao N; Ye M; Zhang Y; Zhang Z; Sun J; Wang Z; Zhang J; Gu Z
    Cancer Lett; 2018 Jul; 427():38-48. PubMed ID: 29679612
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes.
    Pal S; Vishwanath SN; Erdjument-Bromage H; Tempst P; Sif S
    Mol Cell Biol; 2004 Nov; 24(21):9630-45. PubMed ID: 15485929
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein arginine methyltransferase Prmt5-Mep50 methylates histones H2A and H4 and the histone chaperone nucleoplasmin in Xenopus laevis eggs.
    Wilczek C; Chitta R; Woo E; Shabanowitz J; Chait BT; Hunt DF; Shechter D
    J Biol Chem; 2011 Dec; 286(49):42221-42231. PubMed ID: 22009756
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Methylosome protein 50 promotes androgen- and estrogen-independent tumorigenesis.
    Wei TY; Hsia JY; Chiu SC; Su LJ; Juan CC; Lee YC; Chen JM; Chou HY; Huang JY; Huang HM; Yu CT
    Cell Signal; 2014 Dec; 26(12):2940-50. PubMed ID: 25277535
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PRMT1 loss sensitizes cells to PRMT5 inhibition.
    Gao G; Zhang L; Villarreal OD; He W; Su D; Bedford E; Moh P; Shen J; Shi X; Bedford MT; Xu H
    Nucleic Acids Res; 2019 Jun; 47(10):5038-5048. PubMed ID: 30916320
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.