85 related articles for article (PubMed ID: 27270939)
1. Study of Fibronectin Type III-Like Domains Role in Activation of gp130 Receptor.
Stepanov AV; Rybinets AS; Dronina MA; Deev SM
Bull Exp Biol Med; 2016 May; 161(1):72-4. PubMed ID: 27270939
[TBL] [Abstract][Full Text] [Related]
2. Combined deletion of the fibronectin-type III domains and the stalk region results in ligand-independent, constitutive activation of the Interleukin 6 signal-transducing receptor gp130.
Lamertz L; Floss DM; Scheller J
Cytokine; 2018 Oct; 110():428-434. PubMed ID: 29789201
[TBL] [Abstract][Full Text] [Related]
3. Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells.
Stuhlmann-Laeisz C; Lang S; Chalaris A; Krzysztof P; Enge S; Eichler J; Klingmüller U; Samuel M; Ernst M; Rose-John S; Scheller J
Mol Biol Cell; 2006 Jul; 17(7):2986-95. PubMed ID: 16624864
[TBL] [Abstract][Full Text] [Related]
4. Drug design targeting protein-protein interactions (PPIs) using multiple ligand simultaneous docking (MLSD) and drug repositioning: discovery of raloxifene and bazedoxifene as novel inhibitors of IL-6/GP130 interface.
Li H; Xiao H; Lin L; Jou D; Kumari V; Lin J; Li C
J Med Chem; 2014 Feb; 57(3):632-41. PubMed ID: 24456369
[TBL] [Abstract][Full Text] [Related]
5. Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.
Jenkins BJ; Grail D; Nheu T; Najdovska M; Wang B; Waring P; Inglese M; McLoughlin RM; Jones SA; Topley N; Baumann H; Judd LM; Giraud AS; Boussioutas A; Zhu HJ; Ernst M
Nat Med; 2005 Aug; 11(8):845-52. PubMed ID: 16041381
[TBL] [Abstract][Full Text] [Related]
6. gp130 activation is regulated by D2-D3 interdomain connectivity.
Schütt A; Zacharias M; Schneider N; Horn S; Grötzinger J; Rose-John S; Schmidt-Arras D
Biochem J; 2013 Mar; 450(3):487-96. PubMed ID: 23294003
[TBL] [Abstract][Full Text] [Related]
7. Activation of the GP130-STAT3 axis and its potential implications in nonalcoholic fatty liver disease.
Min HK; Mirshahi F; Verdianelli A; Pacana T; Patel V; Park CG; Choi A; Lee JH; Park CB; Ren S; Sanyal AJ
Am J Physiol Gastrointest Liver Physiol; 2015 May; 308(9):G794-803. PubMed ID: 25747354
[TBL] [Abstract][Full Text] [Related]
8. N-linked glycosylation is essential for the stability but not the signaling function of the interleukin-6 signal transducer glycoprotein 130.
Waetzig GH; Chalaris A; Rosenstiel P; Suthaus J; Holland C; Karl N; Vallés Uriarte L; Till A; Scheller J; Grötzinger J; Schreiber S; Rose-John S; Seegert D
J Biol Chem; 2010 Jan; 285(3):1781-9. PubMed ID: 19915009
[TBL] [Abstract][Full Text] [Related]
9. Cell-autonomous hepatocyte-specific GP130 signaling is sufficient to trigger a robust innate immune response in mice.
Schumacher N; Yan K; Gandraß M; Müller M; Krisp C; Häsler R; Carambia A; Nofer JR; Bernardes JP; Khouja M; Thomsen I; Chalupsky K; Bolik J; Hölscher C; Wunderlich T; Herkel J; Rosenstiel P; Schramm C; Schlüter H; Renné T; Mittrücker HW; Rose-John S; Schmidt-Arras D
J Hepatol; 2021 Feb; 74(2):407-418. PubMed ID: 32987028
[TBL] [Abstract][Full Text] [Related]
10. IL-6 induces MUC4 expression through gp130/STAT3 pathway in gastric cancer cell lines.
Mejías-Luque R; Peiró S; Vincent A; Van Seuningen I; de Bolós C
Biochim Biophys Acta; 2008 Oct; 1783(10):1728-36. PubMed ID: 18573283
[TBL] [Abstract][Full Text] [Related]
11. Interleukin-27, a novel cytokine induced by ischemia-reperfusion injury in rat hearts, mediates cardioprotective effects via the gp130/STAT3 pathway.
Ma MC; Wang BW; Yeh TP; Wu JL; Chung TH; Tsui K; Chiang CF; Huang AJ; Huang YT
Basic Res Cardiol; 2015 May; 110(3):22. PubMed ID: 25820907
[TBL] [Abstract][Full Text] [Related]
12. Therapeutic strategies for targeting the IL-6/STAT3 cytokine signaling pathway in inflammatory bowel disease.
Mitsuyama K; Matsumoto S; Masuda J; Yamasakii H; Kuwaki K; Takedatsu H; Sata M
Anticancer Res; 2007; 27(6A):3749-56. PubMed ID: 17970038
[TBL] [Abstract][Full Text] [Related]
13. Determinants governing the potency of STAT3 activation via the individual STAT3-recruiting motifs of gp130.
Lehmann U; Sommer U; Smyczek T; Hörtner M; Frisch W; Volkmer-Engert R; Heinrich PC; Schaper F; Haan S
Cell Signal; 2006 Jan; 18(1):40-9. PubMed ID: 15927449
[TBL] [Abstract][Full Text] [Related]
14. Dimerization of the cytokine receptors gp130 and LIFR analysed in single cells.
Giese B; Roderburg C; Sommerauer M; Wortmann SB; Metz S; Heinrich PC; Müller-Newen G
J Cell Sci; 2005 Nov; 118(Pt 21):5129-40. PubMed ID: 16254248
[TBL] [Abstract][Full Text] [Related]
15. Bile acids inhibit interleukin-6 signaling via gp130 receptor-dependent and -independent pathways in rat liver.
Graf D; Kohlmann C; Haselow K; Gehrmann T; Bode JG; Häussinger D
Hepatology; 2006 Nov; 44(5):1206-17. PubMed ID: 17058237
[TBL] [Abstract][Full Text] [Related]
16. Stimulation of the JAK/STAT pathway by LIF and OSM in the human granulosa cell line COV434.
Pastuschek J; Poetzsch J; Morales-Prieto DM; Schleußner E; Markert UR; Georgiev G
J Reprod Immunol; 2015 Apr; 108():48-55. PubMed ID: 25817464
[TBL] [Abstract][Full Text] [Related]
17. Persistent GP130/STAT3 Signaling Contributes to the Resistance of Doxorubicin, Cisplatin, and MEK Inhibitor in Human Rhabdomyosarcoma Cells.
Wu X; Xiao H; Wang R; Liu L; Li C; Lin J
Curr Cancer Drug Targets; 2016; 16(7):631-8. PubMed ID: 26373715
[TBL] [Abstract][Full Text] [Related]
18. Functional properties of extracellular domains of transducer receptor gp130.
Kostjukova MN; Tupitsyn NN
Biochemistry (Mosc); 2011 Apr; 76(4):394-406. PubMed ID: 21585315
[TBL] [Abstract][Full Text] [Related]
19. Teleost IL-6 promotes antibody production through STAT3 signaling via IL-6R and gp130.
Kaneda M; Odaka T; Suetake H; Tahara D; Miyadai T
Dev Comp Immunol; 2012 Oct; 38(2):224-31. PubMed ID: 22469658
[TBL] [Abstract][Full Text] [Related]
20. Construction of unnatural heterodimeric receptors based on IL-2 and IL-6 receptor subunits.
Ogawa K; Kawahara M; Nagamune T
Biotechnol Prog; 2013; 29(6):1512-8. PubMed ID: 23926072
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
