BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

306 related articles for article (PubMed ID: 27273030)

  • 1. Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity.
    Fusco G; De Simone A; Arosio P; Vendruscolo M; Veglia G; Dobson CM
    Sci Rep; 2016 Jun; 6():27125. PubMed ID: 27273030
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State.
    Runfola M; De Simone A; Vendruscolo M; Dobson CM; Fusco G
    Sci Rep; 2020 Jan; 10(1):204. PubMed ID: 31937832
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour.
    Fusco G; De Simone A; Gopinath T; Vostrikov V; Vendruscolo M; Dobson CM; Veglia G
    Nat Commun; 2014 May; 5():3827. PubMed ID: 24871041
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Solid-state ¹³C NMR reveals annealing of raft-like membranes containing cholesterol by the intrinsically disordered protein α-Synuclein.
    Leftin A; Job C; Beyer K; Brown MF
    J Mol Biol; 2013 Aug; 425(16):2973-87. PubMed ID: 23583776
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multiple tight phospholipid-binding modes of alpha-synuclein revealed by solution NMR spectroscopy.
    Bodner CR; Dobson CM; Bax A
    J Mol Biol; 2009 Jul; 390(4):775-90. PubMed ID: 19481095
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition.
    Man WK; Tahirbegi B; Vrettas MD; Preet S; Ying L; Vendruscolo M; De Simone A; Fusco G
    Nat Commun; 2021 Feb; 12(1):927. PubMed ID: 33568632
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Membrane Interactions of α-Synuclein Revealed by Multiscale Molecular Dynamics Simulations, Markov State Models, and NMR.
    Amos STA; Schwarz TC; Shi J; Cossins BP; Baker TS; Taylor RJ; Konrat R; Sansom MSP
    J Phys Chem B; 2021 Mar; 125(11):2929-2941. PubMed ID: 33719460
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis of synaptic vesicle assembly promoted by α-synuclein.
    Fusco G; Pape T; Stephens AD; Mahou P; Costa AR; Kaminski CF; Kaminski Schierle GS; Vendruscolo M; Veglia G; Dobson CM; De Simone A
    Nat Commun; 2016 Sep; 7():12563. PubMed ID: 27640673
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antiparallel arrangement of the helices of vesicle-bound alpha-synuclein.
    Drescher M; Veldhuis G; van Rooijen BD; Milikisyants S; Subramaniam V; Huber M
    J Am Chem Soc; 2008 Jun; 130(25):7796-7. PubMed ID: 18512917
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Simultaneous IR-Spectroscopic Observation of α-Synuclein, Lipids, and Solvent Reveals an Alternative Membrane-Induced Oligomerization Pathway.
    Fallah MA; Gerding HR; Scheibe C; Drescher M; Karreman C; Schildknecht S; Leist M; Hauser K
    Chembiochem; 2017 Dec; 18(23):2312-2316. PubMed ID: 28980756
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Order and disorder in the physiological membrane binding of α-synuclein.
    Fusco G; Sanz-Hernandez M; De Simone A
    Curr Opin Struct Biol; 2018 Feb; 48():49-57. PubMed ID: 29100107
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In Silico Study of the Mechanism of Binding of the N-Terminal Region of α Synuclein to Synaptic-Like Membranes.
    Navarro-Paya C; Sanz-Hernandez M; De Simone A
    Life (Basel); 2020 Jun; 10(6):. PubMed ID: 32604928
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Curvature dynamics of alpha-synuclein familial Parkinson disease mutants: molecular simulations of the micelle- and bilayer-bound forms.
    Perlmutter JD; Braun AR; Sachs JN
    J Biol Chem; 2009 Mar; 284(11):7177-89. PubMed ID: 19126542
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Membrane-bound structure and energetics of alpha-synuclein.
    Mihajlovic M; Lazaridis T
    Proteins; 2008 Feb; 70(3):761-78. PubMed ID: 17729279
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Membrane packing defects in synaptic vesicles recruit complexin and synuclein.
    Liu J; Bu B; Crowe M; Li D; Diao J; Ji B
    Phys Chem Chem Phys; 2021 Jan; 23(3):2117-2125. PubMed ID: 33437978
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Membrane binding of oligomeric alpha-synuclein depends on bilayer charge and packing.
    van Rooijen BD; Claessens MM; Subramaniam V
    FEBS Lett; 2008 Nov; 582(27):3788-92. PubMed ID: 18930058
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High-resolution structural information of membrane-bound α-synuclein provides insight into the MoA of the anti-Parkinson drug UCB0599.
    Schwarz TC; Beier A; Ledolter K; Gossenreiter T; Höfurthner T; Hartl M; Baker TS; Taylor RJ; Konrat R
    Proc Natl Acad Sci U S A; 2023 Apr; 120(15):e2201910120. PubMed ID: 37027427
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Membrane interactions and fibrillization of α-synuclein play an essential role in membrane disruption.
    Chaudhary H; Stefanovic AN; Subramaniam V; Claessens MM
    FEBS Lett; 2014 Nov; 588(23):4457-63. PubMed ID: 25448986
    [TBL] [Abstract][Full Text] [Related]  

  • 19. α-Synuclein induces both positive mean curvature and negative Gaussian curvature in membranes.
    Braun AR; Sevcsik E; Chin P; Rhoades E; Tristram-Nagle S; Sachs JN
    J Am Chem Soc; 2012 Feb; 134(5):2613-20. PubMed ID: 22211521
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Influence of EGCG on α-synuclein (αS) aggregation and identification of their possible binding mode: A computational study using molecular dynamics simulation.
    Liu X; Zhou S; Shi D; Bai Q; Liu H; Yao X
    Chem Biol Drug Des; 2018 Jan; 91(1):162-171. PubMed ID: 28667699
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.