105 related articles for article (PubMed ID: 27273875)
1. Methylene Homologues of Artemisone: An Unexpected Structure-Activity Relationship and a Possible Implication for the Design of C10-Substituted Artemisinins.
Wu Y; Wu RW; Cheu KW; Williams ID; Krishna S; Slavic K; Gravett AM; Liu WM; Wong HN; Haynes RK
ChemMedChem; 2016 Jul; 11(13):1469-79. PubMed ID: 27273875
[TBL] [Abstract][Full Text] [Related]
2. Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.
Haynes RK; Cheu KW; N'Da D; Coghi P; Monti D
Infect Disord Drug Targets; 2013 Aug; 13(4):217-77. PubMed ID: 24304352
[TBL] [Abstract][Full Text] [Related]
3. Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action.
Haynes RK; Chan WC; Wong HN; Li KY; Wu WK; Fan KM; Sung HH; Williams ID; Prosperi D; Melato S; Coghi P; Monti D
ChemMedChem; 2010 Aug; 5(8):1282-99. PubMed ID: 20629071
[TBL] [Abstract][Full Text] [Related]
4. Antitumour and antimalarial activity of artemisinin-acridine hybrids.
Jones M; Mercer AE; Stocks PA; La Pensée LJ; Cosstick R; Park BK; Kennedy ME; Piantanida I; Ward SA; Davies J; Bray PG; Rawe SL; Baird J; Charidza T; Janneh O; O'Neill PM
Bioorg Med Chem Lett; 2009 Apr; 19(7):2033-7. PubMed ID: 19249201
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological evaluation of extraordinarily potent C-10 carba artemisinin dimers against P. falciparum malaria parasites and HL-60 cancer cells.
Chadwick J; Mercer AE; Park BK; Cosstick R; O'Neill PM
Bioorg Med Chem; 2009 Feb; 17(3):1325-38. PubMed ID: 19136263
[TBL] [Abstract][Full Text] [Related]
6. Interactions between artemisinins and other antimalarial drugs in relation to the cofactor model--a unifying proposal for drug action.
Haynes RK; Cheu KW; Chan HW; Wong HN; Li KY; Tang MM; Chen MJ; Guo ZF; Guo ZH; Sinniah K; Witte AB; Coghi P; Monti D
ChemMedChem; 2012 Dec; 7(12):2204-26. PubMed ID: 23112085
[TBL] [Abstract][Full Text] [Related]
7. Reactions of antimalarial peroxides with each of leucomethylene blue and dihydroflavins: flavin reductase and the cofactor model exemplified.
Haynes RK; Cheu KW; Tang MM; Chen MJ; Guo ZF; Guo ZH; Coghi P; Monti D
ChemMedChem; 2011 Feb; 6(2):279-91. PubMed ID: 21275052
[TBL] [Abstract][Full Text] [Related]
8. Artemisone and Artemiside Are Potent Panreactive Antimalarial Agents That Also Synergize Redox Imbalance in Plasmodium falciparum Transmissible Gametocyte Stages.
Coertzen D; Reader J; van der Watt M; Nondaba SH; Gibhard L; Wiesner L; Smith P; D'Alessandro S; Taramelli D; Wong HN; du Preez JL; Wu RWK; Birkholtz LM; Haynes RK
Antimicrob Agents Chemother; 2018 Aug; 62(8):. PubMed ID: 29866868
[TBL] [Abstract][Full Text] [Related]
9. Antiplasmodial and antitumor activity of dihydroartemisinin analogs derived via the aza-Michael addition reaction.
Feng TS; Guantai EM; Nell MJ; van Rensburg CE; Hoppe HC; Chibale K
Bioorg Med Chem Lett; 2011 May; 21(10):2882-6. PubMed ID: 21489789
[TBL] [Abstract][Full Text] [Related]
10. Antimalarial and antitumor evaluation of novel C-10 non-acetal dimers of 10beta-(2-hydroxyethyl)deoxoartemisinin.
Jeyadevan JP; Bray PG; Chadwick J; Mercer AE; Byrne A; Ward SA; Park BK; Williams DP; Cosstick R; Davies J; Higson AP; Irving E; Posner GH; O'Neill PM
J Med Chem; 2004 Feb; 47(5):1290-8. PubMed ID: 14971909
[TBL] [Abstract][Full Text] [Related]
11. A partial convergence in action of methylene blue and artemisinins: antagonism with chloroquine, a reversal with verapamil, and an insight into the antimalarial activity of chloroquine.
Haynes RK; Cheu KW; Li KY; Tang MM; Wong HN; Chen MJ; Guo ZF; Guo ZH; Coghi P; Monti D
ChemMedChem; 2011 Sep; 6(9):1603-15. PubMed ID: 21994127
[TBL] [Abstract][Full Text] [Related]
12. Artemisone--a highly active antimalarial drug of the artemisinin class.
Haynes RK; Fugmann B; Stetter J; Rieckmann K; Heilmann HD; Chan HW; Cheung MK; Lam WL; Wong HN; Croft SL; Vivas L; Rattray L; Stewart L; Peters W; Robinson BL; Edstein MD; Kotecka B; Kyle DE; Beckermann B; Gerisch M; Radtke M; Schmuck G; Steinke W; Wollborn U; Schmeer K; Römer A
Angew Chem Int Ed Engl; 2006 Mar; 45(13):2082-8. PubMed ID: 16444785
[No Abstract] [Full Text] [Related]
13. Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy.
Posner GH; Paik IH; Sur S; McRiner AJ; Borstnik K; Xie S; Shapiro TA
J Med Chem; 2003 Mar; 46(6):1060-5. PubMed ID: 12620083
[TBL] [Abstract][Full Text] [Related]
14. Assessment of the induction of dormant ring stages in Plasmodium falciparum parasites by artemisone and artemisone entrapped in Pheroid vesicles in vitro.
Grobler L; Chavchich M; Haynes RK; Edstein MD; Grobler AF
Antimicrob Agents Chemother; 2014 Dec; 58(12):7579-82. PubMed ID: 25288088
[TBL] [Abstract][Full Text] [Related]
15. Facile Preparation of
Wu Y; Parapini S; Williams ID; Misiano P; Wong HN; Taramelli D; Basilico N; Haynes RK
Molecules; 2018 Jul; 23(7):. PubMed ID: 30011856
[TBL] [Abstract][Full Text] [Related]
16. Antimalarial activities of (+)-deoxoartemisitene and its novel C-11, 13 derivatives.
Jung M; Lee K; Jung H; Kendrick H; Yardley V; Croft SL
Bioorg Med Chem Lett; 2004 Apr; 14(8):2001-3. PubMed ID: 15050646
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and in vitro biological evaluation of dihydroartemisinyl-chalcone esters.
Smit FJ; van Biljon RA; Birkholtz LM; N'Da DD
Eur J Med Chem; 2015 Jan; 90():33-44. PubMed ID: 25461309
[TBL] [Abstract][Full Text] [Related]
18. The Fe2+-mediated decomposition, PfATP6 binding, and antimalarial activities of artemisone and other artemisinins: the unlikelihood of C-centered radicals as bioactive intermediates.
Haynes RK; Chan WC; Lung CM; Uhlemann AC; Eckstein U; Taramelli D; Parapini S; Monti D; Krishna S
ChemMedChem; 2007 Oct; 2(10):1480-97. PubMed ID: 17768732
[TBL] [Abstract][Full Text] [Related]
19. In vitro activity of artemisone compared with artesunate against Plasmodium falciparum.
Ramharter M; Burkhardt D; Nemeth J; Adegnika AA; Kremsner PG
Am J Trop Med Hyg; 2006 Oct; 75(4):637-9. PubMed ID: 17038685
[TBL] [Abstract][Full Text] [Related]
20. Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo.
Vivas L; Rattray L; Stewart LB; Robinson BL; Fugmann B; Haynes RK; Peters W; Croft SL
J Antimicrob Chemother; 2007 Apr; 59(4):658-65. PubMed ID: 17337512
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
