BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 27275540)

  • 1. GLI1 inhibitor GANT61 exhibits antitumor efficacy in T-cell lymphoma cells through down-regulation of p-STAT3 and SOCS3.
    Geng L; Lu K; Li P; Li X; Zhou X; Li Y; Wang X
    Oncotarget; 2017 Jul; 8(30):48701-48710. PubMed ID: 27275540
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Anti-cell growth and anti-cancer stem cell activities of the non-canonical hedgehog inhibitor GANT61 in triple-negative breast cancer cells.
    Koike Y; Ohta Y; Saitoh W; Yamashita T; Kanomata N; Moriya T; Kurebayashi J
    Breast Cancer; 2017 Sep; 24(5):683-693. PubMed ID: 28144905
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potential role of Shh-Gli1-BMI1 signaling pathway nexus in glioma chemoresistance.
    Shahi MH; Farheen S; Mariyath MP; Castresana JS
    Tumour Biol; 2016 Nov; 37(11):15107-15114. PubMed ID: 27662839
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MiR-155 regulates lymphoma cell proliferation and apoptosis through targeting SOCS3/JAK-STAT3 signaling pathway.
    Li XD; Li XM; Gu JW; Sun XC
    Eur Rev Med Pharmacol Sci; 2017 Nov; 21(22):5153-5159. PubMed ID: 29228427
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Up-regulation of GLI1 in vincristine-resistant rhabdomyosarcoma and Ewing sarcoma.
    Yoon JW; Lamm M; Chandler C; Iannaccone P; Walterhouse D
    BMC Cancer; 2020 Jun; 20(1):511. PubMed ID: 32493277
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma.
    Graab U; Hahn H; Fulda S
    Oncotarget; 2015 Apr; 6(11):8722-35. PubMed ID: 25749378
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy.
    Réda J; Vachtenheim J; Vlčková K; Horák P; Vachtenheim J; Ondrušová L
    Int J Mol Sci; 2018 Sep; 19(9):. PubMed ID: 30201866
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting GLI1 Suppresses Cell Growth and Enhances Chemosensitivity in CD34+ Enriched Acute Myeloid Leukemia Progenitor Cells.
    Long B; Wang LX; Zheng FM; Lai SP; Xu DR; Hu Y; Lin DJ; Zhang XZ; Dong L; Long ZJ; Tong XZ; Liu Q
    Cell Physiol Biochem; 2016; 38(4):1288-302. PubMed ID: 27008269
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors.
    Dagklis A; Demeyer S; De Bie J; Radaelli E; Pauwels D; Degryse S; Gielen O; Vicente C; Vandepoel R; Geerdens E; Uyttebroeck A; Boeckx N; de Bock CE; Cools J
    Blood; 2016 Dec; 128(23):2642-2654. PubMed ID: 27694322
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hedgehog signaling negatively co-regulates BH3-only protein Noxa and TAp73 in TP53-mutated cells.
    Meister MT; Boedicker C; Klingebiel T; Fulda S
    Cancer Lett; 2018 Aug; 429():19-28. PubMed ID: 29702195
    [TBL] [Abstract][Full Text] [Related]  

  • 11. WP1066 exhibits antitumor efficacy in nasal‑type natural killer/T-cell lymphoma cells through downregulation of the STAT3 signaling pathway.
    Geng L; Li X; Zhou X; Fang X; Yuan D; Wang X
    Oncol Rep; 2016 Nov; 36(5):2868-2874. PubMed ID: 27633398
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hedgehog Signal Inhibitor GANT61 Inhibits the Malignant Behavior of Undifferentiated Hepatocellular Carcinoma Cells by Targeting Non-Canonical GLI Signaling.
    Harada K; Ohashi R; Naito K; Kanki K
    Int J Mol Sci; 2020 Apr; 21(9):. PubMed ID: 32354204
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crosstalk between Hedgehog pathway and the glucocorticoid receptor pathway as a basis for combination therapy in T-cell acute lymphoblastic leukemia.
    Bongiovanni D; Tosello V; Saccomani V; Dalla Santa S; Amadori A; Zanovello P; Piovan E
    Oncogene; 2020 Oct; 39(42):6544-6555. PubMed ID: 32917954
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells.
    Bacelar Sacramento de Araújo T; de Oliveira Siquara da Rocha L; Torres Andion Vidal M; Cerqueira Coelho PL; Galvão Dos Reis M; Solano de Freitas Souza B; Botelho Pereira Soares M; Almeida Pereira T; Della Coletta R; Pereira Bezerra D; Borges Dias R; Araújo Gurgel Rocha C
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32846867
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis.
    Lin Z; Li S; Sheng H; Cai M; Ma LY; Hu L; Xu S; Yu LS; Zhang N
    J Cancer Res Clin Oncol; 2016 Dec; 142(12):2469-2478. PubMed ID: 27601167
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Concomitant targeting of Hedgehog signaling and MCL-1 synergistically induces cell death in Hedgehog-driven cancer cells.
    Meister MT; Boedicker C; Linder B; Kögel D; Klingebiel T; Fulda S
    Cancer Lett; 2019 Nov; 465():1-11. PubMed ID: 31465840
    [TBL] [Abstract][Full Text] [Related]  

  • 17. GLI1 reduces drug sensitivity by regulating cell cycle through PI3K/AKT/GSK3/CDK pathway in acute myeloid leukemia.
    Zhou C; Du J; Zhao L; Liu W; Zhao T; Liang H; Fang P; Zhang K; Zeng H
    Cell Death Dis; 2021 Mar; 12(3):231. PubMed ID: 33658491
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anti-proliferation of breast cancer cells with itraconazole: Hedgehog pathway inhibition induces apoptosis and autophagic cell death.
    Wang X; Wei S; Zhao Y; Shi C; Liu P; Zhang C; Lei Y; Zhang B; Bai B; Huang Y; Zhang H
    Cancer Lett; 2017 Jan; 385():128-136. PubMed ID: 27810405
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells.
    Oladapo HO; Tarpley M; Sauer SJ; Addo KA; Ingram SM; Strepay D; Ehe BK; Chdid L; Trinkler M; Roques JR; Darr DB; Fleming JM; Devi GR; Williams KP
    Cancer Lett; 2017 Dec; 411():136-149. PubMed ID: 28965853
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GLI1-targeting drugs induce replication stress and homologous recombination deficiency and synergize with PARP-targeted therapies in triple negative breast cancer cells.
    Mani C; Tripathi K; Omy TR; Reedy M; Manne U; Palle K
    Biochim Biophys Acta Mol Basis Dis; 2022 Feb; 1868(2):166300. PubMed ID: 34748904
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.