BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

657 related articles for article (PubMed ID: 27281560)

  • 1. Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis.
    Geng F; Cheng X; Wu X; Yoo JY; Cheng C; Guo JY; Mo X; Ru P; Hurwitz B; Kim SH; Otero J; Puduvalli V; Lefai E; Ma J; Nakano I; Horbinski C; Kaur B; Chakravarti A; Guo D
    Clin Cancer Res; 2016 Nov; 22(21):5337-5348. PubMed ID: 27281560
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SOAT1: A Suitable Target for Therapy in High-Grade Astrocytic Glioma?
    Löhr M; Härtig W; Schulze A; Kroiß M; Sbiera S; Lapa C; Mages B; Strobel S; Hundt JE; Bohnert S; Kircher S; Janaki-Raman S; Monoranu CM
    Int J Mol Sci; 2022 Mar; 23(7):. PubMed ID: 35409086
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lipid Metabolism in Glioblastoma: From De Novo Synthesis to Storage.
    Kou Y; Geng F; Guo D
    Biomedicines; 2022 Aug; 10(8):. PubMed ID: 36009491
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth.
    Ru P; Hu P; Geng F; Mo X; Cheng C; Yoo JY; Cheng X; Wu X; Guo JY; Nakano I; Lefai E; Kaur B; Chakravarti A; Guo D
    Cell Rep; 2016 Aug; 16(6):1527-1535. PubMed ID: 27477273
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lipid droplets, potential biomarker and metabolic target in glioblastoma.
    Geng F; Guo D
    Intern Med Rev (Wash D C); 2017 May; 3(5):. PubMed ID: 29034362
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway.
    Guo D; Reinitz F; Youssef M; Hong C; Nathanson D; Akhavan D; Kuga D; Amzajerdi AN; Soto H; Zhu S; Babic I; Tanaka K; Dang J; Iwanami A; Gini B; Dejesus J; Lisiero DD; Huang TT; Prins RM; Wen PY; Robins HI; Prados MD; Deangelis LM; Mellinghoff IK; Mehta MP; James CD; Chakravarti A; Cloughesy TF; Tontonoz P; Mischel PS
    Cancer Discov; 2011 Oct; 1(5):442-56. PubMed ID: 22059152
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Perilipin-mediated lipid droplet formation in adipocytes promotes sterol regulatory element-binding protein-1 processing and triacylglyceride accumulation.
    Takahashi Y; Shinoda A; Furuya N; Harada E; Arimura N; Ichi I; Fujiwara Y; Inoue J; Sato R
    PLoS One; 2013; 8(5):e64605. PubMed ID: 23734208
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells.
    Geng F; Zhong Y; Su H; Lefai E; Magaki S; Cloughesy TF; Yong WH; Chakravarti A; Guo D
    Cell Rep; 2023 Jul; 42(7):112790. PubMed ID: 37436895
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting SREBP-1-driven lipid metabolism to treat cancer.
    Guo D; Bell EH; Mischel P; Chakravarti A
    Curr Pharm Des; 2014; 20(15):2619-26. PubMed ID: 23859617
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SREBF1/SREBP-1 concurrently regulates lipid synthesis and lipophagy to maintain lipid homeostasis and tumor growth.
    Geng F; Guo D
    Autophagy; 2024 May; 20(5):1183-1185. PubMed ID: 37927089
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Berberine suppresses colon cancer cell proliferation by inhibiting the SCAP/SREBP-1 signaling pathway-mediated lipogenesis.
    Liu Y; Hua W; Li Y; Xian X; Zhao Z; Liu C; Zou J; Li J; Fang X; Zhu Y
    Biochem Pharmacol; 2020 Apr; 174():113776. PubMed ID: 31874145
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of 25-hydroxycholesterol on cholesterol esterification and sterol regulatory element-binding protein processing are dissociable: implications for cholesterol movement to the regulatory pool in the endoplasmic reticulum.
    Du X; Pham YH; Brown AJ
    J Biol Chem; 2004 Nov; 279(45):47010-6. PubMed ID: 15317807
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SREBP maintains lipid biosynthesis and viability of cancer cells under lipid- and oxygen-deprived conditions and defines a gene signature associated with poor survival in glioblastoma multiforme.
    Lewis CA; Brault C; Peck B; Bensaad K; Griffiths B; Mitter R; Chakravarty P; East P; Dankworth B; Alibhai D; Harris AL; Schulze A
    Oncogene; 2015 Oct; 34(40):5128-40. PubMed ID: 25619842
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Toxic effects of phytol and retinol on human glioblastoma cells are associated with modulation of cholesterol and fatty acid biosynthetic pathways.
    Facchini G; Ignarro RS; Rodrigues-Silva E; Vieira AS; Lopes-Cendes I; Castilho RF; Rogerio F
    J Neurooncol; 2018 Feb; 136(3):435-443. PubMed ID: 29159775
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum.
    Esquejo RM; Roqueta-Rivera M; Shao W; Phelan PE; Seneviratne U; Am Ende CW; Hershberger PM; Machamer CE; Espenshade PJ; Osborne TF
    Cell Chem Biol; 2021 Feb; 28(2):169-179.e7. PubMed ID: 33096051
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dysregulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence.
    Ettinger SL; Sobel R; Whitmore TG; Akbari M; Bradley DR; Gleave ME; Nelson CC
    Cancer Res; 2004 Mar; 64(6):2212-21. PubMed ID: 15026365
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SOAT1 deficiency attenuates atherosclerosis by regulating inflammation and cholesterol transportation via HO-1 pathway.
    Wu N; Li RQ; Li L
    Biochem Biophys Res Commun; 2018 Jun; 501(2):343-350. PubMed ID: 29567472
    [TBL] [Abstract][Full Text] [Related]  

  • 18. cAMP response element binding protein H mediates fenofibrate-induced suppression of hepatic lipogenesis.
    Min AK; Jeong JY; Go Y; Choi YK; Kim YD; Lee IK; Park KG
    Diabetologia; 2013 Feb; 56(2):412-22. PubMed ID: 23150180
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Knockdown of sterol O-acyltransferase 1 (SOAT1) suppresses SCD1-mediated lipogenesis and cancer procession in prostate cancer.
    Liu Y; Wang Y; Hao S; Qin Y; Wu Y
    Prostaglandins Other Lipid Mediat; 2021 Apr; 153():106537. PubMed ID: 33454379
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of an insulin-induced gene binding compound that ameliorates nonalcoholic steatohepatitis by inhibiting sterol regulatory element-binding protein-mediated lipogenesis.
    Jiang SY; Yang X; Yang Z; Li JW; Xu MQ; Qu YX; Tang JJ; Li YF; Wang L; Shao YW; Meng XY; Hu H; Song BL; Rao Y; Qi W
    Hepatology; 2022 Nov; 76(5):1466-1481. PubMed ID: 35102596
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.