BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 27291650)

  • 21. Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains.
    Zhang G; Plotnikov AN; Rusinova E; Shen T; Morohashi K; Joshua J; Zeng L; Mujtaba S; Ohlmeyer M; Zhou MM
    J Med Chem; 2013 Nov; 56(22):9251-64. PubMed ID: 24144283
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Importance of a crystalline water network in docking-based virtual screening: a case study of BRD4.
    Zhong H; Wang Z; Wang X; Liu H; Li D; Liu H; Yao X; Hou T
    Phys Chem Chem Phys; 2019 Dec; 21(45):25276-25289. PubMed ID: 31701109
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Development of 4,5-dihydro-benzodiazepinone derivatives as a new chemical series of BRD4 inhibitors.
    Li J; Wang P; Zhou B; Shi J; Liu J; Li X; Fan L; Zheng Y; Ouyang L
    Eur J Med Chem; 2016 Oct; 121():294-299. PubMed ID: 27266999
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Structural basis and binding properties of the second bromodomain of Brd4 with acetylated histone tails.
    Liu Y; Wang X; Zhang J; Huang H; Ding B; Wu J; Shi Y
    Biochemistry; 2008 Jun; 47(24):6403-17. PubMed ID: 18500820
    [TBL] [Abstract][Full Text] [Related]  

  • 25. BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia.
    Roe JS; Mercan F; Rivera K; Pappin DJ; Vakoc CR
    Mol Cell; 2015 Jun; 58(6):1028-39. PubMed ID: 25982114
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Segmental Isotope Labelling of an Individual Bromodomain of a Tandem Domain BRD4 Using Sortase A.
    Williams FP; Milbradt AG; Embrey KJ; Bobby R
    PLoS One; 2016; 11(4):e0154607. PubMed ID: 27128490
    [TBL] [Abstract][Full Text] [Related]  

  • 27. 4-Acyl Pyrrole Derivatives Yield Novel Vectors for Designing Inhibitors of the Acetyl-Lysine Recognition Site of BRD4(1).
    Hügle M; Lucas X; Weitzel G; Ostrovskyi D; Breit B; Gerhardt S; Einsle O; Günther S; Wohlwend D
    J Med Chem; 2016 Feb; 59(4):1518-30. PubMed ID: 26731611
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells.
    Gonzales-Cope M; Sidoli S; Bhanu NV; Won KJ; Garcia BA
    BMC Genomics; 2016 Feb; 17():95. PubMed ID: 26847871
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Development of a Time-Resolved Fluorescence Resonance Energy Transfer Ultrahigh-Throughput Screening Assay for Targeting the NSD3 and MYC Interaction.
    Xiong J; Pecchi VG; Qui M; Ivanov AA; Mo X; Niu Q; Chen X; Fu H; Du Y
    Assay Drug Dev Technol; 2018; 16(2):96-106. PubMed ID: 29634317
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Accumulation of heterochromatin components on the terminal repeat sequence of Kaposi's sarcoma-associated herpesvirus mediated by the latency-associated nuclear antigen.
    Sakakibara S; Ueda K; Nishimura K; Do E; Ohsaki E; Okuno T; Yamanishi K
    J Virol; 2004 Jul; 78(14):7299-310. PubMed ID: 15220403
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Inhibits Major Histocompatibility Complex Class II Expression by Disrupting Enhanceosome Assembly through Binding with the Regulatory Factor X Complex.
    Thakker S; Purushothaman P; Gupta N; Challa S; Cai Q; Verma SC
    J Virol; 2015 May; 89(10):5536-56. PubMed ID: 25740990
    [TBL] [Abstract][Full Text] [Related]  

  • 32. BET Bromodomain Blockade Mitigates Intimal Hyperplasia in Rat Carotid Arteries.
    Wang B; Zhang M; Takayama T; Shi X; Roenneburg DA; Kent KC; Guo LW
    EBioMedicine; 2015 Nov; 2(11):1650-61. PubMed ID: 26870791
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The methyltransferase NSD3 promotes antiviral innate immunity via direct lysine methylation of IRF3.
    Wang C; Wang Q; Xu X; Xie B; Zhao Y; Li N; Cao X
    J Exp Med; 2017 Dec; 214(12):3597-3610. PubMed ID: 29101251
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Structural basis for activity regulation of MLL family methyltransferases.
    Li Y; Han J; Zhang Y; Cao F; Liu Z; Li S; Wu J; Hu C; Wang Y; Shuai J; Chen J; Cao L; Li D; Shi P; Tian C; Zhang J; Dou Y; Li G; Chen Y; Lei M
    Nature; 2016 Feb; 530(7591):447-52. PubMed ID: 26886794
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis.
    Dey A; Chitsaz F; Abbasi A; Misteli T; Ozato K
    Proc Natl Acad Sci U S A; 2003 Jul; 100(15):8758-63. PubMed ID: 12840145
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Catching BETs by viruses.
    Zandian M; Chen IP; Byrareddy SN; Fujimori DG; Ott M; Kutateladze TG
    Biochim Biophys Acta Gene Regul Mech; 2022 Oct; 1865(7):194859. PubMed ID: 35985635
    [TBL] [Abstract][Full Text] [Related]  

  • 37. BET Bromodomain as a Target of Epigenetic Therapy.
    Noguchi-Yachide T
    Chem Pharm Bull (Tokyo); 2016; 64(6):540-7. PubMed ID: 27250788
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin-Remodeling Complexes.
    Conrad RJ; Fozouni P; Thomas S; Sy H; Zhang Q; Zhou MM; Ott M
    Mol Cell; 2017 Sep; 67(6):1001-1012.e6. PubMed ID: 28844864
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Targeting BET bromodomains for cancer treatment.
    Jung M; Gelato KA; Fernández-Montalván A; Siegel S; Haendler B
    Epigenomics; 2015; 7(3):487-501. PubMed ID: 26077433
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A Genetically Encoded FRET Probe to Detect Intranucleosomal Histone H3K9 or H3K14 Acetylation Using BRD4, a BET Family Member.
    Nakaoka S; Sasaki K; Ito A; Nakao Y; Yoshida M
    ACS Chem Biol; 2016 Mar; 11(3):729-33. PubMed ID: 25946208
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.