BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 27292187)

  • 1. Persistent Activation of NF-κB in BRCA1-Deficient Mammary Progenitors Drives Aberrant Proliferation and Accumulation of DNA Damage.
    Sau A; Lau R; Cabrita MA; Nolan E; Crooks PA; Visvader JE; Pratt MA
    Cell Stem Cell; 2016 Jul; 19(1):52-65. PubMed ID: 27292187
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NF-κB at the Crossroads of Normal Mammary Gland Biology and the Pathogenesis and Prevention of
    Sau A; Cabrita MA; Pratt MAC
    Cancer Prev Res (Phila); 2018 Feb; 11(2):69-80. PubMed ID: 29101208
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RelB/p52 NF-kappaB complexes rescue an early delay in mammary gland development in transgenic mice with targeted superrepressor IkappaB-alpha expression and promote carcinogenesis of the mammary gland.
    Demicco EG; Kavanagh KT; Romieu-Mourez R; Wang X; Shin SR; Landesman-Bollag E; Seldin DC; Sonenshein GE
    Mol Cell Biol; 2005 Nov; 25(22):10136-47. PubMed ID: 16260626
    [TBL] [Abstract][Full Text] [Related]  

  • 4. c-Kit is required for growth and survival of the cells of origin of Brca1-mutation-associated breast cancer.
    Regan JL; Kendrick H; Magnay FA; Vafaizadeh V; Groner B; Smalley MJ
    Oncogene; 2012 Feb; 31(7):869-83. PubMed ID: 21765473
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BRCA1 Attenuates Progesterone Effects on Proliferation and NFκB Activation in Normal Human Mammary Epithelial Cells.
    Hilton HN; Patterson McDonald LJ; Santucci N; van der Bent FR; Silvestri A; Graham JD; Clarke CL
    J Mammary Gland Biol Neoplasia; 2019 Sep; 24(3):257-270. PubMed ID: 31104199
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers.
    Nolan E; Vaillant F; Branstetter D; Pal B; Giner G; Whitehead L; Lok SW; Mann GB; ; Rohrbach K; Huang LY; Soriano R; Smyth GK; Dougall WC; Visvader JE; Lindeman GJ
    Nat Med; 2016 Aug; 22(8):933-9. PubMed ID: 27322743
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Induction of alternative NF-κB within TAg-induced basal mammary tumors in activation-resistant inhibitor of κ-B kinase (IKKα) mutant mice.
    Ould-Brahim F; Sau A; Carr DA; Jiang T; Pratt MAC
    Tumour Biol; 2022; 44(1):187-203. PubMed ID: 36093651
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alpha-6 integrin deletion delays the formation of Brca1/p53-deficient basal-like breast tumors by restricting luminal progenitor cell expansion.
    Faraldo MM; Romagnoli M; Wallon L; Dubus P; Deugnier MA; Fre S
    Breast Cancer Res; 2024 Jun; 26(1):91. PubMed ID: 38835038
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA; Mehmi I; Atlas E; Colomer R; Lupu R
    Int J Oncol; 2004 Mar; 24(3):591-608. PubMed ID: 14767544
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells.
    Ma Y; Katiyar P; Jones LP; Fan S; Zhang Y; Furth PA; Rosen EM
    Mol Endocrinol; 2006 Jan; 20(1):14-34. PubMed ID: 16109739
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The canonical NF-kappaB pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population.
    Pratt MA; Tibbo E; Robertson SJ; Jansson D; Hurst K; Perez-Iratxeta C; Lau R; Niu MY
    Oncogene; 2009 Jul; 28(30):2710-22. PubMed ID: 19483731
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aberrant activation of NF-κB signaling in mammary epithelium leads to abnormal growth and ductal carcinoma in situ.
    Barham W; Chen L; Tikhomirov O; Onishko H; Gleaves L; Stricker TP; Blackwell TS; Yull FE
    BMC Cancer; 2015 Sep; 15():647. PubMed ID: 26424146
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differing effects of breast cancer 1, early onset (BRCA1) and ataxia-telangiectasia mutated (ATM) mutations on cellular responses to ionizing radiation.
    Mamon HJ; Dahlberg W; Azzam EI; Nagasawa H; Muto MG; Little JB
    Int J Radiat Biol; 2003 Oct; 79(10):817-29. PubMed ID: 14630541
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The DNA damage signalling kinase ATM is aberrantly reduced or lost in BRCA1/BRCA2-deficient and ER/PR/ERBB2-triple-negative breast cancer.
    Tommiska J; Bartkova J; Heinonen M; Hautala L; Kilpivaara O; Eerola H; Aittomäki K; Hofstetter B; Lukas J; von Smitten K; Blomqvist C; Ristimäki A; Heikkilä P; Bartek J; Nevanlinna H
    Oncogene; 2008 Apr; 27(17):2501-6. PubMed ID: 17982490
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer.
    Wang H; Xiang D; Liu B; He A; Randle HJ; Zhang KX; Dongre A; Sachs N; Clark AP; Tao L; Chen Q; Botchkarev VV; Xie Y; Dai N; Clevers H; Li Z; Livingston DM
    Cell; 2019 Jun; 178(1):135-151.e19. PubMed ID: 31251913
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage.
    Aleyasin H; Cregan SP; Iyirhiaro G; O'Hare MJ; Callaghan SM; Slack RS; Park DS
    J Neurosci; 2004 Mar; 24(12):2963-73. PubMed ID: 15044535
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesis.
    Xing L; Bushnell TP; Carlson L; Tai Z; Tondravi M; Siebenlist U; Young F; Boyce BF
    J Bone Miner Res; 2002 Jul; 17(7):1200-10. PubMed ID: 12096833
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NF-κB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes.
    Volcic M; Karl S; Baumann B; Salles D; Daniel P; Fulda S; Wiesmüller L
    Nucleic Acids Res; 2012 Jan; 40(1):181-95. PubMed ID: 21908405
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATM gene regulates oxygen-glucose deprivation-induced nuclear factor-kappaB DNA-binding activity and downstream apoptotic cascade in mouse cerebrovascular endothelial cells.
    Yin KJ; Chen SD; Lee JM; Xu J; Hsu CY
    Stroke; 2002 Oct; 33(10):2471-7. PubMed ID: 12364740
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Persistence of unrepaired DNA double strand breaks caused by inhibition of ATM does not lead to radio-sensitisation in the absence of NF-κB activation.
    Veuger SJ; Durkacz BW
    DNA Repair (Amst); 2011 Feb; 10(2):235-44. PubMed ID: 21144805
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.