These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Semisynthetic Approach to the Analysis of Tumor Suppressor PTEN Ubiquitination. Iwase R; Dempsey DR; Whedon SD; Jiang H; Palanski BA; Deng B; Cole PA J Am Chem Soc; 2023 Mar; 145(11):6039-6044. PubMed ID: 36897111 [TBL] [Abstract][Full Text] [Related]
5. WWP2 is a physiological ubiquitin ligase for phosphatase and tensin homolog (PTEN) in mice. Li H; Zhang P; Zhang Q; Li C; Zou W; Chang Z; Cui CP; Zhang L J Biol Chem; 2018 Jun; 293(23):8886-8899. PubMed ID: 29685889 [TBL] [Abstract][Full Text] [Related]
6. SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway. Liu J; Wan L; Liu P; Inuzuka H; Liu J; Wang Z; Wei W Oncotarget; 2014 Feb; 5(4):1026-37. PubMed ID: 24657926 [TBL] [Abstract][Full Text] [Related]
7. The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4. Ahn Y; Hwang CY; Lee SR; Kwon KS; Lee C Biochem J; 2008 Jun; 412(2):331-8. PubMed ID: 18307411 [TBL] [Abstract][Full Text] [Related]
8. Oncogenic role of the E3 ubiquitin ligase NEDD4-1, a PTEN negative regulator, in non-small-cell lung carcinomas. Amodio N; Scrima M; Palaia L; Salman AN; Quintiero A; Franco R; Botti G; Pirozzi P; Rocco G; De Rosa N; Viglietto G Am J Pathol; 2010 Nov; 177(5):2622-34. PubMed ID: 20889565 [TBL] [Abstract][Full Text] [Related]
9. Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc. Kwak YD; Wang B; Pan W; Xu H; Jiang X; Liao FF J Biol Chem; 2010 Mar; 285(13):9847-9857. PubMed ID: 20100827 [TBL] [Abstract][Full Text] [Related]
10. Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth. Hsia HE; Kumar R; Luca R; Takeda M; Courchet J; Nakashima J; Wu S; Goebbels S; An W; Eickholt BJ; Polleux F; Rotin D; Wu H; Rossner MJ; Bagni C; Rhee JS; Brose N; Kawabe H Proc Natl Acad Sci U S A; 2014 Sep; 111(36):13205-10. PubMed ID: 25157163 [TBL] [Abstract][Full Text] [Related]
11. Crucial role of the C-terminus of PTEN in antagonizing NEDD4-1-mediated PTEN ubiquitination and degradation. Wang X; Shi Y; Wang J; Huang G; Jiang X Biochem J; 2008 Sep; 414(2):221-9. PubMed ID: 18498243 [TBL] [Abstract][Full Text] [Related]
12. p34 is a novel regulator of the oncogenic behavior of NEDD4-1 and PTEN. Hong SW; Moon JH; Kim JS; Shin JS; Jung KA; Lee WK; Jeong SY; Hwang JJ; Lee SJ; Suh YA; Kim I; Nam KY; Han S; Kim JE; Kim KP; Hong YS; Lee JL; Lee WJ; Choi EK; Lee JS; Jin DH; Kim TW Cell Death Differ; 2014 Jan; 21(1):146-60. PubMed ID: 24141722 [TBL] [Abstract][Full Text] [Related]
13. The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization. Fouladkou F; Landry T; Kawabe H; Neeb A; Lu C; Brose N; Stambolic V; Rotin D Proc Natl Acad Sci U S A; 2008 Jun; 105(25):8585-90. PubMed ID: 18562292 [TBL] [Abstract][Full Text] [Related]
14. NEDD4: The founding member of a family of ubiquitin-protein ligases. Boase NA; Kumar S Gene; 2015 Feb; 557(2):113-22. PubMed ID: 25527121 [TBL] [Abstract][Full Text] [Related]
16. The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters. Aleidi SM; Howe V; Sharpe LJ; Yang A; Rao G; Brown AJ; Gelissen IC J Biol Chem; 2015 Oct; 290(40):24604-13. PubMed ID: 26296893 [TBL] [Abstract][Full Text] [Related]
17. NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway. Eide PW; Cekaite L; Danielsen SA; Eilertsen IA; Kjenseth A; Fykerud TA; Ågesen TH; Bruun J; Rivedal E; Lothe RA; Leithe E Cell Signal; 2013 Jan; 25(1):12-8. PubMed ID: 22974840 [TBL] [Abstract][Full Text] [Related]
18. The antiproliferative response of indole-3-carbinol in human melanoma cells is triggered by an interaction with NEDD4-1 and disruption of wild-type PTEN degradation. Aronchik I; Kundu A; Quirit JG; Firestone GL Mol Cancer Res; 2014 Nov; 12(11):1621-1634. PubMed ID: 25009292 [TBL] [Abstract][Full Text] [Related]
19. Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions. Yang B; Kumar S Cell Death Differ; 2010 Jan; 17(1):68-77. PubMed ID: 19557014 [TBL] [Abstract][Full Text] [Related]
20. NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN. Wang X; Trotman LC; Koppie T; Alimonti A; Chen Z; Gao Z; Wang J; Erdjument-Bromage H; Tempst P; Cordon-Cardo C; Pandolfi PP; Jiang X Cell; 2007 Jan; 128(1):129-39. PubMed ID: 17218260 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]