BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

885 related articles for article (PubMed ID: 27297870)

  • 1. Andrographolide inhibits hypoxia-induced HIF-1α-driven endothelin 1 secretion by activating Nrf2/HO-1 and promoting the expression of prolyl hydroxylases 2/3 in human endothelial cells.
    Lin HC; Su SL; Lu CY; Lin AH; Lin WC; Liu CS; Yang YC; Wang HM; Lii CK; Chen HW
    Environ Toxicol; 2017 Mar; 32(3):918-930. PubMed ID: 27297870
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Andrographolide inhibits hypoxia-induced hypoxia-inducible factor 1α and endothelin 1 expression through the heme oxygenase 1/CO/cGMP/MKP-5 pathways in EA.hy926 cells.
    Lin HC; Su SL; Lin WC; Lin AH; Yang YC; Lii CK; Chen HW
    Environ Toxicol; 2018 Mar; 33(3):269-279. PubMed ID: 29165873
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endothelin-1 regulates hypoxia-inducible factor-1α and -2α stability through prolyl hydroxylase domain 2 inhibition in human lymphatic endothelial cells.
    Caprara V; Scappa S; Garrafa E; Di Castro V; Rosanò L; Bagnato A; Spinella F
    Life Sci; 2014 Nov; 118(2):185-90. PubMed ID: 24607784
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Andrographolide inhibits TNFα-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the PI3K/Akt/Nrf2 and PI3K/Akt/AP-1 pathways in human endothelial cells.
    Lu CY; Yang YC; Li CC; Liu KL; Lii CK; Chen HW
    Biochem Pharmacol; 2014 Sep; 91(1):40-50. PubMed ID: 24998495
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation.
    Seo K; Seo S; Ki SH; Shin SM
    Free Radic Biol Med; 2016 Dec; 101():511-523. PubMed ID: 27840318
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Andrographolide stimulates p38 mitogen-activated protein kinase-nuclear factor erythroid-2-related factor 2-heme oxygenase 1 signaling in primary cerebral endothelial cells for definite protection against ischemic stroke in rats.
    Yen TL; Chen RJ; Jayakumar T; Lu WJ; Hsieh CY; Hsu MJ; Yang CH; Chang CC; Lin YK; Lin KH; Sheu JR
    Transl Res; 2016 Apr; 170():57-72. PubMed ID: 26746802
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RUNX3 inhibits hypoxia-inducible factor-1α protein stability by interacting with prolyl hydroxylases in gastric cancer cells.
    Lee SH; Bae SC; Kim KW; Lee YM
    Oncogene; 2014 Mar; 33(11):1458-67. PubMed ID: 23542169
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.
    Spinella F; Rosanò L; Del Duca M; Di Castro V; Nicotra MR; Natali PG; Bagnato A
    PLoS One; 2010 Jun; 5(6):e11241. PubMed ID: 20574527
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NRF2 blockade suppresses colon tumor angiogenesis by inhibiting hypoxia-induced activation of HIF-1α.
    Kim TH; Hur EG; Kang SJ; Kim JA; Thapa D; Lee YM; Ku SK; Jung Y; Kwak MK
    Cancer Res; 2011 Mar; 71(6):2260-75. PubMed ID: 21278237
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 15-Deoxy-Δ
    Choi JE; Kim JH; Song NY; Suh J; Kim DH; Kim SJ; Na HK; Nadas J; Dong Z; Cha YN; Surh YJ
    Free Radic Res; 2016 Oct; 50(10):1140-1152. PubMed ID: 27598034
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Andrographolide exerts anti-hepatitis C virus activity by up-regulating haeme oxygenase-1 via the p38 MAPK/Nrf2 pathway in human hepatoma cells.
    Lee JC; Tseng CK; Young KC; Sun HY; Wang SW; Chen WC; Lin CK; Wu YH
    Br J Pharmacol; 2014 Jan; 171(1):237-52. PubMed ID: 24117426
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Andrographolide inhibits the migration, invasion and matrix metalloproteinase expression of rheumatoid arthritis fibroblast-like synoviocytes via inhibition of HIF-1α signaling.
    Li GF; Qin YH; Du PQ
    Life Sci; 2015 Sep; 136():67-72. PubMed ID: 26141990
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of heme oxygenase 1 and inhibition of tumor necrosis factor alpha-induced intercellular adhesion molecule expression by andrographolide in EA.hy926 cells.
    Yu AL; Lu CY; Wang TS; Tsai CW; Liu KL; Cheng YP; Chang HC; Lii CK; Chen HW
    J Agric Food Chem; 2010 Jul; 58(13):7641-8. PubMed ID: 20536138
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 3,3'-Diindolylmethane inhibits VEGF expression through the HIF-1α and NF-κB pathways in human retinal pigment epithelial cells under chemical hypoxic conditions.
    Park H; Lee DS; Yim MJ; Choi YH; Park S; Seo SK; Choi JS; Jang WH; Yea SS; Park WS; Lee CM; Jung WK; Choi IW
    Int J Mol Med; 2015 Jul; 36(1):301-8. PubMed ID: 25955241
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NADPH oxidase-mitochondria axis-derived ROS mediate arsenite-induced HIF-1α stabilization by inhibiting prolyl hydroxylases activity.
    Li YN; Xi MM; Guo Y; Hai CX; Yang WL; Qin XJ
    Toxicol Lett; 2014 Jan; 224(2):165-74. PubMed ID: 24188932
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential transcriptional regulation of hypoxia-inducible factor-1α by arsenite under normoxia and hypoxia: involvement of Nrf2.
    Al Taleb Z; Petry A; Chi TF; Mennerich D; Görlach A; Dimova EY; Kietzmann T
    J Mol Med (Berl); 2016 Oct; 94(10):1153-1166. PubMed ID: 27286880
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Andrographolide Activates Keap1/Nrf2/ARE/HO-1 Pathway in HT22 Cells and Suppresses Microglial Activation by A
    Seo JY; Pyo E; An JP; Kim J; Sung SH; Oh WK
    Mediators Inflamm; 2017; 2017():5906189. PubMed ID: 28373747
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Miltirone protects human EA.hy926 endothelial cells from oxidized low-density lipoprotein-derived oxidative stress via a heme oxygenase-1 and MAPK/Nrf2 dependent pathway.
    Zhang L; Zhang H; Li X; Jia B; Yang Y; Zhou P; Li P; Chen J
    Phytomedicine; 2016 Dec; 23(14):1806-1813. PubMed ID: 27912883
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.
    Berchner-Pfannschmidt U; Yamac H; Trinidad B; Fandrey J
    J Biol Chem; 2007 Jan; 282(3):1788-96. PubMed ID: 17060326
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Itaconate Suppresses Formation of Neutrophil Extracellular Traps (NETs): Involvement of Hypoxia-Inducible Factor 1α (Hif-1α) and Heme Oxygenase (HO-1).
    Burczyk G; Cichon I; Kolaczkowska E
    Front Immunol; 2022; 13():864638. PubMed ID: 35837403
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 45.