BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 27301780)

  • 1. Ontogeny of Hepatic Drug Transporters as Quantified by LC-MS/MS Proteomics.
    Prasad B; Gaedigk A; Vrana M; Gaedigk R; Leeder JS; Salphati L; Chu X; Xiao G; Hop C; Evers R; Gan L; Unadkat JD
    Clin Pharmacol Ther; 2016 Oct; 100(4):362-70. PubMed ID: 27301780
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sex.
    Prasad B; Evers R; Gupta A; Hop CE; Salphati L; Shukla S; Ambudkar SV; Unadkat JD
    Drug Metab Dispos; 2014 Jan; 42(1):78-88. PubMed ID: 24122874
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ontogeny of human hepatic and intestinal transporter gene expression during childhood: age matters.
    Mooij MG; Schwarz UI; de Koning BA; Leeder JS; Gaedigk R; Samsom JN; Spaans E; van Goudoever JB; Tibboel D; Kim RB; de Wildt SN
    Drug Metab Dispos; 2014 Aug; 42(8):1268-74. PubMed ID: 24829289
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3.
    Misaka S; Knop J; Singer K; Hoier E; Keiser M; Müller F; Glaeser H; König J; Fromm MF
    Mol Pharm; 2016 Feb; 13(2):512-9. PubMed ID: 26702643
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Raltegravir has a low propensity to cause clinical drug interactions through inhibition of major drug transporters: an in vitro evaluation.
    Rizk ML; Houle R; Chan GH; Hafey M; Rhee EG; Chu X
    Antimicrob Agents Chemother; 2014; 58(3):1294-301. PubMed ID: 24295974
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The effect of breast cancer resistance protein, multidrug resistant protein 1, and organic anion-transporting polypeptide 1B3 on the antitumor efficacy of the lipophilic camptothecin 7-t-butyldimethylsilyl-10-hydroxycamptothecin (AR-67) in vitro.
    Tsakalozou E; Adane ED; Kuo KL; Daily A; Moscow JA; Leggas M
    Drug Metab Dispos; 2013 Jul; 41(7):1404-13. PubMed ID: 23620484
    [TBL] [Abstract][Full Text] [Related]  

  • 7. OATP1B3 Expression and Function is Modulated by Coexpression with OCT1, OATP1B1, and NTCP.
    Zhang Y; Ruggiero M; Hagenbuch B
    Drug Metab Dispos; 2020 Aug; 48(8):622-630. PubMed ID: 32482756
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs.
    Ieiri I; Higuchi S; Sugiyama Y
    Expert Opin Drug Metab Toxicol; 2009 Jul; 5(7):703-29. PubMed ID: 19442037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein.
    Knop J; Misaka S; Singer K; Hoier E; Müller F; Glaeser H; König J; Fromm MF
    PLoS One; 2015; 10(10):e0139370. PubMed ID: 26426900
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of Drug-Drug Interactions of Ensitrelvir, a SARS-CoV-2 3CL Protease Inhibitor, With Transporter Substrates Based on In Vitro and Clinical Studies.
    Shimizu R; Matsuzaki T; Oka R; Sonoyama T; Fukuhara T; Kuwata A; Matsuo Y; Kubota R
    J Clin Pharmacol; 2023 Aug; 63(8):918-927. PubMed ID: 37043676
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein Abundance of Drug Transporters in Human Hepatitis C Livers.
    Droździk M; Lapczuk-Romanska J; Wenzel C; Skalski Ł; Szeląg-Pieniek S; Post M; Syczewska M; Kurzawski M; Oswald S
    Int J Mol Sci; 2022 Jul; 23(14):. PubMed ID: 35887291
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation of the endothelin receptor antagonists ambrisentan, bosentan, macitentan, and sitaxsentan as hepatobiliary transporter inhibitors and substrates in sandwich-cultured human hepatocytes.
    Lepist EI; Gillies H; Smith W; Hao J; Hubert C; St Claire RL; Brouwer KR; Ray AS
    PLoS One; 2014; 9(1):e87548. PubMed ID: 24498134
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Influence of MRP3 Genetics and Hepatic Expression Ontogeny for Morphine Disposition in Neonatal and Pediatric Patients.
    Hahn D; Fukuda T; Euteneuer JC; Mizuno T; Vinks AA; Sadhasivam S; Emoto C
    J Clin Pharmacol; 2020 Aug; 60(8):992-998. PubMed ID: 32090339
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.
    Yamada A; Maeda K; Kamiyama E; Sugiyama D; Kondo T; Shiroyanagi Y; Nakazawa H; Okano T; Adachi M; Schuetz JD; Adachi Y; Hu Z; Kusuhara H; Sugiyama Y
    Drug Metab Dispos; 2007 Dec; 35(12):2166-76. PubMed ID: 17823233
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular mechanisms governing different pharmacokinetics of ginsenosides and potential for ginsenoside-perpetrated herb-drug interactions on OATP1B3.
    Jiang R; Dong J; Li X; Du F; Jia W; Xu F; Wang F; Yang J; Niu W; Li C
    Br J Pharmacol; 2015 Feb; 172(4):1059-73. PubMed ID: 25297453
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Contribution of hepatic organic anion-transporting polypeptides to docetaxel uptake and clearance.
    Lee HH; Leake BF; Teft W; Tirona RG; Kim RB; Ho RH
    Mol Cancer Ther; 2015 Apr; 14(4):994-1003. PubMed ID: 25695959
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Organic Anion Transporting Polypeptide-Mediated Hepatic Uptake of Glucuronide Metabolites of Androgens.
    Li CY; Gupta A; Gáborik Z; Kis E; Prasad B
    Mol Pharmacol; 2020 Sep; 98(3):234-242. PubMed ID: 32587096
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.
    Nassif A; Jia J; Keiser M; Oswald S; Modess C; Nagel S; Weitschies W; Hosten N; Siegmund W; Kühn JP
    Radiology; 2012 Sep; 264(3):741-50. PubMed ID: 22771883
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lipopolysaccharide-mediated regulation of hepatic transporter mRNA levels in rats.
    Cherrington NJ; Slitt AL; Li N; Klaassen CD
    Drug Metab Dispos; 2004 Jul; 32(7):734-41. PubMed ID: 15205389
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Meta-analysis of expression of hepatic organic anion-transporting polypeptide (OATP) transporters in cellular systems relative to human liver tissue.
    Badée J; Achour B; Rostami-Hodjegan A; Galetin A
    Drug Metab Dispos; 2015 Apr; 43(4):424-32. PubMed ID: 25564656
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.