BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 27307499)

  • 61. Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1.
    Yergey AL; Blank PS; Cologna SM; Backlund PS; Porter FD; Darling AJ
    PLoS One; 2017; 12(4):e0175478. PubMed ID: 28414792
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Niemann-Pick Disease Type C: Induced Pluripotent Stem Cell-Derived Neuronal Cells for Modeling Neural Disease and Evaluating Drug Efficacy.
    Yu D; Swaroop M; Wang M; Baxa U; Yang R; Yan Y; Coksaygan T; DeTolla L; Marugan JJ; Austin CP; McKew JC; Gong DW; Zheng W
    J Biomol Screen; 2014 Sep; 19(8):1164-73. PubMed ID: 24907126
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Reduced cerebellar neurodegeneration after combined therapy with cyclodextrin/allopregnanolone and miglustat in NPC1: a mouse model of Niemann-Pick type C1 disease.
    Maass F; Petersen J; Hovakimyan M; Schmitt O; Witt M; Hawlitschka A; Lukas J; Rolfs A; Wree A
    J Neurosci Res; 2015 Mar; 93(3):433-42. PubMed ID: 25400034
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Combined therapy with cyclodextrin/allopregnanolone and miglustat improves motor but not cognitive functions in Niemann-Pick Type C1 mice.
    Hovakimyan M; Maass F; Petersen J; Holzmann C; Witt M; Lukas J; Frech MJ; Hübner R; Rolfs A; Wree A
    Neuroscience; 2013 Nov; 252():201-11. PubMed ID: 23948640
    [TBL] [Abstract][Full Text] [Related]  

  • 65. Pulmonary function and pathology in hydroxypropyl-beta-cyclodextin-treated and untreated Npc1⁻/⁻ mice.
    Muralidhar A; Borbon IA; Esharif DM; Ke W; Manacheril R; Daines M; Erickson RP
    Mol Genet Metab; 2011 Jun; 103(2):142-7. PubMed ID: 21459030
    [TBL] [Abstract][Full Text] [Related]  

  • 66. A marked paucity of granule cells in the developing cerebellum of the Npc1(-/-) mouse is corrected by a single injection of hydroxypropyl-β-cyclodextrin.
    Nusca S; Canterini S; Palladino G; Bruno F; Mangia F; Erickson RP; Fiorenza MT
    Neurobiol Dis; 2014 Oct; 70():117-26. PubMed ID: 24969023
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Decreased neural stem cell proliferation and olfaction in mouse models of Niemann-Pick C1 disease and the response to hydroxypropyl-β-cyclodextrin.
    Dragotto J; Palladino G; Canterini S; Caporali P; Patil R; Fiorenza MT; Erickson RP
    J Appl Genet; 2019 Nov; 60(3-4):357-365. PubMed ID: 31485950
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Anesthetic management of pediatric patients with Niemann-Pick disease type C for intrathecal 2-hydroxypropyl-β-cyclodextrin injection.
    Ulloa ML; Froyshteter AB; Kret LN; Chang DP; Sarah GE; McCarthy RJ; Barnes SD; Berry-Kravis EM
    Paediatr Anaesth; 2020 Jul; 30(7):766-772. PubMed ID: 32349180
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Impact of the Niemann-Pick c1 Gene Mutation on the Total Cellular Glycomics of CHO Cells.
    Furukawa JI; Soga M; Okada K; Yokota I; Piao J; Irie T; Era T; Shinohara Y
    J Proteome Res; 2017 Aug; 16(8):2802-2810. PubMed ID: 28628327
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Cyclodextrin mediates rapid changes in lipid balance in Npc1-/- mice without carrying cholesterol through the bloodstream.
    Taylor AM; Liu B; Mari Y; Liu B; Repa JJ
    J Lipid Res; 2012 Nov; 53(11):2331-42. PubMed ID: 22892156
    [TBL] [Abstract][Full Text] [Related]  

  • 71. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder.
    Brown A; Patel S; Ward C; Lorenz A; Ortiz M; DuRoss A; Wieghardt F; Esch A; Otten EG; Heiser LM; Korolchuk VI; Sun C; Sarkar S; Sahay G
    Sci Rep; 2016 Aug; 6():31750. PubMed ID: 27572704
    [TBL] [Abstract][Full Text] [Related]  

  • 72. Phenotypic expression of swallowing function in Niemann-Pick disease type C1.
    Solomon BI; Muñoz AM; Sinaii N; Farhat NM; Smith AC; Bianconi S; Dang Do A; Backman MC; Machielse L; Porter FD
    Orphanet J Rare Dis; 2022 Sep; 17(1):342. PubMed ID: 36064725
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Long-term efficacy of intrathecal cyclodextrin in patients with Niemann-Pick disease type C.
    Matsuo M; Sakakibara T; Sakiyama Y; So T; Kosuga M; Kakiuchi T; Ichinose F; Nakamura T; Ishitsuka Y; Irie T
    Brain Dev; 2024 May; 46(5):207-212. PubMed ID: 38448301
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells.
    Abi-Mosleh L; Infante RE; Radhakrishnan A; Goldstein JL; Brown MS
    Proc Natl Acad Sci U S A; 2009 Nov; 106(46):19316-21. PubMed ID: 19884502
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Application of a simple methodology to analyze Hydroxypropyl-β-Cyclodextrin in urine using HPLC-LS in early Niemann-Pick disease type C patient.
    Matencio A; Alcaráz-Gómez MA; García-Carmona F; Arias B; López-Nicolás JM
    J Chromatogr B Analyt Technol Biomed Life Sci; 2018 Sep; 1093-1094():47-51. PubMed ID: 29990712
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Swallowing characterization of adult-onset Niemann-Pick, type C1 patients.
    Solomon BI; Muñoz AM; Sinaii N; Mohamed H; Farhat NM; Alexander D; Do AD; Porter FD
    Orphanet J Rare Dis; 2024 Jun; 19(1):231. PubMed ID: 38863022
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Identification of Brain-Specific Treatment Effects in NPC1 Disease by Focusing on Cellular and Molecular Changes of Sphingosine-1-Phosphate Metabolism.
    Gläser A; Hammerl F; Gräler MH; Coldewey SM; Völkner C; Frech MJ; Yang F; Luo J; Tönnies E; von Bohlen Und Halbach O; Brandt N; Heimes D; Neßlauer AM; Korenke GC; Owczarek-Lipska M; Neidhardt J; Rolfs A; Wree A; Witt M; Bräuer AU
    Int J Mol Sci; 2020 Jun; 21(12):. PubMed ID: 32599915
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium.
    Lloyd-Evans E; Morgan AJ; He X; Smith DA; Elliot-Smith E; Sillence DJ; Churchill GC; Schuchman EH; Galione A; Platt FM
    Nat Med; 2008 Nov; 14(11):1247-55. PubMed ID: 18953351
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells.
    Rosenbaum AI; Zhang G; Warren JD; Maxfield FR
    Proc Natl Acad Sci U S A; 2010 Mar; 107(12):5477-82. PubMed ID: 20212119
    [TBL] [Abstract][Full Text] [Related]  

  • 80. NMR analysis reveals significant differences in the plasma metabolic profiles of Niemann Pick C1 patients, heterozygous carriers, and healthy controls.
    Probert F; Ruiz-Rodado V; Vruchte DT; Nicoli ER; Claridge TDW; Wassif CA; Farhat N; Porter FD; Platt FM; Grootveld M
    Sci Rep; 2017 Jul; 7(1):6320. PubMed ID: 28740230
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.