BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

292 related articles for article (PubMed ID: 27309669)

  • 1. Molecular dissection of valproic acid effects in acute myeloid leukemia identifies predictive networks.
    Rücker FG; Lang KM; Fütterer M; Komarica V; Schmid M; Döhner H; Schlenk RF; Döhner K; Knudsen S; Bullinger L
    Epigenetics; 2016 Jul; 11(7):517-25. PubMed ID: 27309669
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The histone deacetylase inhibitor valproic acid alters sensitivity towards all trans retinoic acid in acute myeloblastic leukemia cells.
    Trus MR; Yang L; Suarez Saiz F; Bordeleau L; Jurisica I; Minden MD
    Leukemia; 2005 Jul; 19(7):1161-8. PubMed ID: 15902297
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells.
    Liu S; Klisovic RB; Vukosavljevic T; Yu J; Paschka P; Huynh L; Pang J; Neviani P; Liu Z; Blum W; Chan KK; Perrotti D; Marcucci G
    J Pharmacol Exp Ther; 2007 Jun; 321(3):953-60. PubMed ID: 17389244
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia.
    McCormack E; Haaland I; Venås G; Forthun RB; Huseby S; Gausdal G; Knappskog S; Micklem DR; Lorens JB; Bruserud O; Gjertsen BT
    Leukemia; 2012 May; 26(5):910-7. PubMed ID: 22064349
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Valproic acid may exerts its cytotoxic effect through rassf1a expression induction in acute myeloid leukemia.
    Davood ZA; Shamsi S; Ghaedi H; Sahand RI; Mojtaba G; Mahdi T; Reza M; Ebrahimi MJ; Miri-Moosavi RS; Boosaliki S; Davood OM
    Tumour Biol; 2016 Aug; 37(8):11001-6. PubMed ID: 26894600
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Time- and residue-specific differences in histone acetylation induced by VPA and SAHA in AML1/ETO-positive leukemia cells.
    Barbetti V; Gozzini A; Cheloni G; Marzi I; Fabiani E; Santini V; Dello Sbarba P; Rovida E
    Epigenetics; 2013 Feb; 8(2):210-9. PubMed ID: 23321683
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Valproic acid exerts differential effects on CXCR4 expression in leukemic cells.
    Gul H; Marquez-Curtis LA; Jahroudi N; Larratt LM; Janowska-Wieczorek A
    Leuk Res; 2010 Feb; 34(2):235-42. PubMed ID: 19539992
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Results of a phase 2 study of valproic acid alone or in combination with all-trans retinoic acid in 75 patients with myelodysplastic syndrome and relapsed or refractory acute myeloid leukemia.
    Kuendgen A; Knipp S; Fox F; Strupp C; Hildebrandt B; Steidl C; Germing U; Haas R; Gattermann N
    Ann Hematol; 2005 Dec; 84 Suppl 1():61-6. PubMed ID: 16270213
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination with all-trans retinoic acid in patients with acute myeloid leukemia.
    Kuendgen A; Schmid M; Schlenk R; Knipp S; Hildebrandt B; Steidl C; Germing U; Haas R; Dohner H; Gattermann N
    Cancer; 2006 Jan; 106(1):112-9. PubMed ID: 16323176
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Elevated FOSB-expression; a potential marker of valproate sensitivity in AML.
    Khanim FL; Bradbury CA; Arrazi J; Hayden RE; Rye A; Basu S; MacWhannell A; Sawers A; Griffiths M; Cook M; Freeman S; Nightingale KP; Grimwade D; Falciani F; Turner BM; Bunce CM; Craddock C
    Br J Haematol; 2009 Feb; 144(3):332-41. PubMed ID: 19036090
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hydroxyurea synergizes with valproic acid in wild-type p53 acute myeloid leukaemia.
    Leitch C; Osdal T; Andresen V; Molland M; Kristiansen S; Nguyen XN; Bruserud Ø; Gjertsen BT; McCormack E
    Oncotarget; 2016 Feb; 7(7):8105-18. PubMed ID: 26812881
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Valproic acid triggers differentiation and apoptosis in AML1/ETO-positive leukemic cells specifically.
    Zapotocky M; Mejstrikova E; Smetana K; Stary J; Trka J; Starkova J
    Cancer Lett; 2012 Jun; 319(2):144-153. PubMed ID: 22261333
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vivo anti-myeloma activity and modulation of gene expression profile induced by valproic acid, a histone deacetylase inhibitor.
    Neri P; Tagliaferri P; Di Martino MT; Calimeri T; Amodio N; Bulotta A; Ventura M; Eramo PO; Viscomi C; Arbitrio M; Rossi M; Caraglia M; Munshi NC; Anderson KC; Tassone P
    Br J Haematol; 2008 Nov; 143(4):520-31. PubMed ID: 18986388
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Downregulation of c-Myc is critical for valproic acid-induced growth arrest and myeloid differentiation of acute myeloid leukemia.
    Cheng YC; Lin H; Huang MJ; Chow JM; Lin S; Liu HE
    Leuk Res; 2007 Oct; 31(10):1403-11. PubMed ID: 17445886
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Valproic acid synergistically enhances the cytotoxicity of clofarabine in pediatric acute myeloid leukemia cells.
    Xie C; Edwards H; Lograsso SB; Buck SA; Matherly LH; Taub JW; Ge Y
    Pediatr Blood Cancer; 2012 Dec; 59(7):1245-51. PubMed ID: 22488775
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparison of the anticancer properties of a novel valproic acid prodrug to leading histone deacetylase inhibitors.
    Tarasenko N; Chekroun-Setti H; Nudelman A; Rephaeli A
    J Cell Biochem; 2018 Apr; 119(4):3417-3428. PubMed ID: 29135083
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The histone deacetylase inhibitor valproic acid potently augments gemtuzumab ozogamicin-induced apoptosis in acute myeloid leukemic cells.
    ten Cate B; Samplonius DF; Bijma T; de Leij LF; Helfrich W; Bremer E
    Leukemia; 2007 Feb; 21(2):248-52. PubMed ID: 17122863
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Clinical trial of valproic acid and all-trans retinoic acid in patients with poor-risk acute myeloid leukemia.
    Bug G; Ritter M; Wassmann B; Schoch C; Heinzel T; Schwarz K; Romanski A; Kramer OH; Kampfmann M; Hoelzer D; Neubauer A; Ruthardt M; Ottmann OG
    Cancer; 2005 Dec; 104(12):2717-25. PubMed ID: 16294345
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanisms of synergistic antileukemic interactions between valproic acid and cytarabine in pediatric acute myeloid leukemia.
    Xie C; Edwards H; Xu X; Zhou H; Buck SA; Stout ML; Yu Q; Rubnitz JE; Matherly LH; Taub JW; Ge Y
    Clin Cancer Res; 2010 Nov; 16(22):5499-510. PubMed ID: 20889917
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high-risk acute myeloid leukemia.
    Cimino G; Lo-Coco F; Fenu S; Travaglini L; Finolezzi E; Mancini M; Nanni M; Careddu A; Fazi F; Padula F; Fiorini R; Spiriti MA; Petti MC; Venditti A; Amadori S; Mandelli F; Pelicci PG; Nervi C
    Cancer Res; 2006 Sep; 66(17):8903-11. PubMed ID: 16951208
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.