1609 related articles for article (PubMed ID: 27310874)
21. Bim upregulation by histone deacetylase inhibitors mediates interactions with the Bcl-2 antagonist ABT-737: evidence for distinct roles for Bcl-2, Bcl-xL, and Mcl-1.
Chen S; Dai Y; Pei XY; Grant S
Mol Cell Biol; 2009 Dec; 29(23):6149-69. PubMed ID: 19805519
[TBL] [Abstract][Full Text] [Related]
22. BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells.
Huang S; Sinicrope FA
Cancer Res; 2008 Apr; 68(8):2944-51. PubMed ID: 18413764
[TBL] [Abstract][Full Text] [Related]
23. Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak.
Lindqvist LM; Heinlein M; Huang DC; Vaux DL
Proc Natl Acad Sci U S A; 2014 Jun; 111(23):8512-7. PubMed ID: 24912196
[TBL] [Abstract][Full Text] [Related]
24. Myeloid cell leukemia-1 is an important apoptotic survival factor in triple-negative breast cancer.
Goodwin CM; Rossanese OW; Olejniczak ET; Fesik SW
Cell Death Differ; 2015 Dec; 22(12):2098-106. PubMed ID: 26045046
[TBL] [Abstract][Full Text] [Related]
25. Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1's inhibitory effect on Bak.
Wang C; Youle RJ
Oncogene; 2012 Jun; 31(26):3177-89. PubMed ID: 22056880
[TBL] [Abstract][Full Text] [Related]
26. Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells.
Matsumoto M; Nakajima W; Seike M; Gemma A; Tanaka N
Biochem Biophys Res Commun; 2016 Apr; 473(2):490-6. PubMed ID: 26996126
[TBL] [Abstract][Full Text] [Related]
27. Regulation of stress-induced nuclear protein redistribution: a new function of Bax and Bak uncoupled from Bcl-x(L).
Lindenboim L; Blacher E; Borner C; Stein R
Cell Death Differ; 2010 Feb; 17(2):346-59. PubMed ID: 19816507
[TBL] [Abstract][Full Text] [Related]
28. AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts.
González-Gironès DM; Moncunill-Massaguer C; Iglesias-Serret D; Cosialls AM; Pérez-Perarnau A; Palmeri CM; Rubio-Patiño C; Villunger A; Pons G; Gil J
Apoptosis; 2013 Aug; 18(8):1008-16. PubMed ID: 23605481
[TBL] [Abstract][Full Text] [Related]
29. Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xL.
Le Pen J; Maillet L; Sarosiek K; Vuillier C; Gautier F; Montessuit S; Martinou JC; Letaï A; Braun F; Juin PP
Cell Death Dis; 2016 Feb; 7(2):e2083. PubMed ID: 26844698
[TBL] [Abstract][Full Text] [Related]
30. Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim.
Jabbour AM; Heraud JE; Daunt CP; Kaufmann T; Sandow J; O'Reilly LA; Callus BA; Lopez A; Strasser A; Vaux DL; Ekert PG
Cell Death Differ; 2009 Apr; 16(4):555-63. PubMed ID: 19079139
[TBL] [Abstract][Full Text] [Related]
31. The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver.
Kodama T; Hikita H; Kawaguchi T; Saito Y; Tanaka S; Shigekawa M; Shimizu S; Li W; Miyagi T; Kanto T; Hiramatsu N; Tatsumi T; Takehara T
J Biol Chem; 2013 Oct; 288(42):30009-30018. PubMed ID: 23986435
[TBL] [Abstract][Full Text] [Related]
32. The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.
Sung ES; Park KJ; Choi HJ; Kim CH; Kim YS
Exp Cell Res; 2012 Aug; 318(13):1564-76. PubMed ID: 22513214
[TBL] [Abstract][Full Text] [Related]
33. Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis.
Clohessy JG; Zhuang J; de Boer J; Gil-Gómez G; Brady HJ
J Biol Chem; 2006 Mar; 281(9):5750-9. PubMed ID: 16380381
[TBL] [Abstract][Full Text] [Related]
34. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.
van Delft MF; Wei AH; Mason KD; Vandenberg CJ; Chen L; Czabotar PE; Willis SN; Scott CL; Day CL; Cory S; Adams JM; Roberts AW; Huang DC
Cancer Cell; 2006 Nov; 10(5):389-99. PubMed ID: 17097561
[TBL] [Abstract][Full Text] [Related]
35. In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins.
Senft D; Weber A; Saathoff F; Berking C; Heppt MV; Kammerbauer C; Rothenfusser S; Kellner S; Kurgyis Z; Besch R; Häcker G
Cell Death Dis; 2015 Nov; 6(11):e1996. PubMed ID: 26610208
[TBL] [Abstract][Full Text] [Related]
36. BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response.
Sarosiek KA; Chi X; Bachman JA; Sims JJ; Montero J; Patel L; Flanagan A; Andrews DW; Sorger P; Letai A
Mol Cell; 2013 Sep; 51(6):751-65. PubMed ID: 24074954
[TBL] [Abstract][Full Text] [Related]
37. B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins.
Renault TT; Elkholi R; Bharti A; Chipuk JE
J Biol Chem; 2014 Sep; 289(38):26481-26491. PubMed ID: 25096574
[TBL] [Abstract][Full Text] [Related]
38. Sevoflurane post-conditioning protects primary rat cortical neurons against oxygen-glucose deprivation/resuscitation via down-regulation in mitochondrial apoptosis axis of Bid, Bim, Puma-Bax and Bak mediated by Erk1/2.
Zhang LM; Zhao XC; Sun WB; Li R; Jiang XJ
J Neurol Sci; 2015 Oct; 357(1-2):80-7. PubMed ID: 26152828
[TBL] [Abstract][Full Text] [Related]
39. BIM-mediated membrane insertion of the BAK pore domain is an essential requirement for apoptosis.
Weber K; Harper N; Schwabe J; Cohen GM
Cell Rep; 2013 Oct; 5(2):409-20. PubMed ID: 24120870
[TBL] [Abstract][Full Text] [Related]
40. Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B.
Rooswinkel RW; van de Kooij B; Verheij M; Borst J
Cell Death Dis; 2012 Aug; 3(8):e366. PubMed ID: 22875003
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]