BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 27311542)

  • 1. Pathways controlling dNTP pools to maintain genome stability.
    Rudd SG; Valerie NCK; Helleday T
    DNA Repair (Amst); 2016 Aug; 44():193-204. PubMed ID: 27311542
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The roles of human MTH1, MTH2 and MTH3 proteins in maintaining genome stability under oxidative stress.
    Hashiguchi K; Hayashi M; Sekiguchi M; Umezu K
    Mutat Res; 2018 Mar; 808():10-19. PubMed ID: 29482072
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool.
    Scaletti ER; Vallin KS; Bräutigam L; Sarno A; Warpman Berglund U; Helleday T; Stenmark P; Jemth AS
    J Biol Chem; 2020 Apr; 295(15):4761-4772. PubMed ID: 32144205
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MTH1 deficiency selectively increases non-cytotoxic oxidative DNA damage in lung cancer cells: more bad news than good?
    Abbas HHK; Alhamoudi KMH; Evans MD; Jones GDD; Foster SS
    BMC Cancer; 2018 Apr; 18(1):423. PubMed ID: 29661172
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2.
    Carter M; Jemth AS; Hagenkort A; Page BD; Gustafsson R; Griese JJ; Gad H; Valerie NC; Desroses M; Boström J; Warpman Berglund U; Helleday T; Stenmark P
    Nat Commun; 2015 Aug; 6():7871. PubMed ID: 26238318
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Mutations induced by damaged DNA precursors and their prevention by nucleotide pool sanitization and DNA repair enzymes].
    Kamiya H
    Seikagaku; 2008 May; 80(5):413-6. PubMed ID: 18575227
    [No Abstract]   [Full Text] [Related]  

  • 7. Oxidized purine nucleotides, genome instability and neurodegeneration.
    Ventura I; Russo MT; De Luca G; Bignami M
    Mutat Res; 2010 Nov; 703(1):59-65. PubMed ID: 20601098
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Investigation of micronucleus induction in MTH1 knockdown cells exposed to UVA, UVB or UVC.
    Fotouhi A; Cornella N; Ramezani M; Wojcik A; Haghdoost S
    Mutat Res Genet Toxicol Environ Mutagen; 2015 Nov; 793():161-5. PubMed ID: 26520386
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
    Gad H; Koolmeister T; Jemth AS; Eshtad S; Jacques SA; Ström CE; Svensson LM; Schultz N; Lundbäck T; Einarsdottir BO; Saleh A; Göktürk C; Baranczewski P; Svensson R; Berntsson RP; Gustafsson R; Strömberg K; Sanjiv K; Jacques-Cordonnier MC; Desroses M; Gustavsson AL; Olofsson R; Johansson F; Homan EJ; Loseva O; Bräutigam L; Johansson L; Höglund A; Hagenkort A; Pham T; Altun M; Gaugaz FZ; Vikingsson S; Evers B; Henriksson M; Vallin KS; Wallner OA; Hammarström LG; Wiita E; Almlöf I; Kalderén C; Axelsson H; Djureinovic T; Puigvert JC; Häggblad M; Jeppsson F; Martens U; Lundin C; Lundgren B; Granelli I; Jensen AJ; Artursson P; Nilsson JA; Stenmark P; Scobie M; Berglund UW; Helleday T
    Nature; 2014 Apr; 508(7495):215-21. PubMed ID: 24695224
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Validation and development of MTH1 inhibitors for treatment of cancer.
    Warpman Berglund U; Sanjiv K; Gad H; Kalderén C; Koolmeister T; Pham T; Gokturk C; Jafari R; Maddalo G; Seashore-Ludlow B; Chernobrovkin A; Manoilov A; Pateras IS; Rasti A; Jemth AS; Almlöf I; Loseva O; Visnes T; Einarsdottir BO; Gaugaz FZ; Saleh A; Platzack B; Wallner OA; Vallin KS; Henriksson M; Wakchaure P; Borhade S; Herr P; Kallberg Y; Baranczewski P; Homan EJ; Wiita E; Nagpal V; Meijer T; Schipper N; Rudd SG; Bräutigam L; Lindqvist A; Filppula A; Lee TC; Artursson P; Nilsson JA; Gorgoulis VG; Lehtiö J; Zubarev RA; Scobie M; Helleday T
    Ann Oncol; 2016 Dec; 27(12):2275-2283. PubMed ID: 27827301
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhancing Repair of Oxidative DNA Damage with Small-Molecule Activators of MTH1.
    Lee Y; Onishi Y; McPherson L; Kietrys AM; Hebenbrock M; Jun YW; Das I; Adimoolam S; Ji D; Mohsen MG; Ford JM; Kool ET
    ACS Chem Biol; 2022 Aug; 17(8):2074-2087. PubMed ID: 35830623
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oxidized deoxyribonucleotides, mutagenesis, and cancer.
    Mathews CK
    FASEB J; 2017 Jan; 31(1):11-13. PubMed ID: 27729413
    [No Abstract]   [Full Text] [Related]  

  • 13. Modulation of oxidative mutagenesis and carcinogenesis by polymorphic forms of human DNA repair enzymes.
    Nohmi T; Kim SR; Yamada M
    Mutat Res; 2005 Dec; 591(1-2):60-73. PubMed ID: 16081110
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PRDX1 and MTH1 cooperate to prevent ROS-mediated inhibition of telomerase.
    Ahmed W; Lingner J
    Genes Dev; 2018 May; 32(9-10):658-669. PubMed ID: 29773556
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides.
    Nakabeppu Y; Kajitani K; Sakamoto K; Yamaguchi H; Tsuchimoto D
    DNA Repair (Amst); 2006 Jul; 5(7):761-72. PubMed ID: 16621731
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An increase of oxidised nucleotides activates DNA damage checkpoint pathway that regulates post-embryonic development in Caenorhabditis elegans.
    Sanada Y; Zhang-Akiyama QM
    Mutagenesis; 2014 Mar; 29(2):107-14. PubMed ID: 24435662
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Preliminary investigation on DNA oxidation impairment repair enzymes MTH1, OGG1 and UTYH as well as their interactions].
    Ke YB; Xu XY; Zhuang ZX
    Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi; 2009 May; 27(5):310-3. PubMed ID: 19538855
    [No Abstract]   [Full Text] [Related]  

  • 18. Mitotic MTH1 Inhibitors in Treatment of Cancer.
    Helleday T
    Cancer Treat Res; 2023; 186():223-237. PubMed ID: 37978139
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mammalian enzymes for preventing transcriptional errors caused by oxidative damage.
    Ishibashi T; Hayakawa H; Ito R; Miyazawa M; Yamagata Y; Sekiguchi M
    Nucleic Acids Res; 2005; 33(12):3779-84. PubMed ID: 16002790
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MTH1, an 8-oxo-2'-deoxyguanosine triphosphatase, and MYH, a DNA glycosylase, cooperate to inhibit mutations induced by chronic exposure to oxidative stress of ionising radiation.
    Shakeri Manesh S; Sangsuwan T; Pour Khavari A; Fotouhi A; Emami SN; Haghdoost S
    Mutagenesis; 2017 May; 32(3):389-396. PubMed ID: 28340109
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.