179 related articles for article (PubMed ID: 27311542)
21. Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue.
McPherson LA; Troccoli CI; Ji D; Bowles AE; Gardiner ML; Mohsen MG; Nagathihalli NS; Nguyen DM; Robbins DJ; Merchant NB; Kool ET; Rai P; Ford JM
DNA Repair (Amst); 2019 Nov; 83():102644. PubMed ID: 31311767
[TBL] [Abstract][Full Text] [Related]
22. Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase.
Nakabeppu Y; Oka S; Sheng Z; Tsuchimoto D; Sakumi K
Mutat Res; 2010 Nov; 703(1):51-8. PubMed ID: 20542142
[TBL] [Abstract][Full Text] [Related]
23. Mechanisms of MTH1 inhibition-induced DNA strand breaks: The slippery slope from the oxidized nucleotide pool to genotoxic damage.
Rai P; Sobol RW
DNA Repair (Amst); 2019 May; 77():18-26. PubMed ID: 30852368
[TBL] [Abstract][Full Text] [Related]
24. Oxidative damage in nucleic acids and Parkinson's disease.
Nakabeppu Y; Tsuchimoto D; Yamaguchi H; Sakumi K
J Neurosci Res; 2007 Apr; 85(5):919-34. PubMed ID: 17279544
[TBL] [Abstract][Full Text] [Related]
25. MTH1 protects platelet mitochondria from oxidative damage and regulates platelet function and thrombosis.
Ding Y; Gui X; Chu X; Sun Y; Zhang S; Tong H; Ju W; Li Y; Sun Z; Xu M; Li Z; Andrews RK; Gardiner EE; Zeng L; Xu K; Qiao J
Nat Commun; 2023 Aug; 14(1):4829. PubMed ID: 37563135
[TBL] [Abstract][Full Text] [Related]
26. Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability.
Arczewska KD; Baumeier C; Kassahun H; Sengupta T; Bjørås M; Kuśmierek JT; Nilsen H
DNA Repair (Amst); 2011 Feb; 10(2):176-87. PubMed ID: 21111690
[TBL] [Abstract][Full Text] [Related]
27. Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids.
Nakabeppu Y; Sakumi K; Sakamoto K; Tsuchimoto D; Tsuzuki T; Nakatsu Y
Biol Chem; 2006 Apr; 387(4):373-9. PubMed ID: 16606334
[TBL] [Abstract][Full Text] [Related]
28. Sanitation enzymes: Exquisite surveillance of the noncanonical nucleotide pool to safeguard the genetic blueprint.
Broderick K; Moutaoufik MT; Aly KA; Babu M
Semin Cancer Biol; 2023 Sep; 94():11-20. PubMed ID: 37211293
[TBL] [Abstract][Full Text] [Related]
29. AtNUDX1, an 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase, is responsible for eliminating oxidized nucleotides in Arabidopsis.
Yoshimura K; Ogawa T; Ueda Y; Shigeoka S
Plant Cell Physiol; 2007 Oct; 48(10):1438-49. PubMed ID: 17804481
[TBL] [Abstract][Full Text] [Related]
30. Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival.
Kawamura T; Kawatani M; Muroi M; Kondoh Y; Futamura Y; Aono H; Tanaka M; Honda K; Osada H
Sci Rep; 2016 May; 6():26521. PubMed ID: 27210421
[TBL] [Abstract][Full Text] [Related]
31. MutT Homolog 1 (MTH1): The Silencing of a Target.
Papeo G
J Med Chem; 2016 Mar; 59(6):2343-5. PubMed ID: 26924380
[TBL] [Abstract][Full Text] [Related]
32. MTH1 Inhibitor TH588 Disturbs Mitotic Progression and Induces Mitosis-Dependent Accumulation of Genomic 8-oxodG.
Rudd SG; Gad H; Sanjiv K; Amaral N; Hagenkort A; Groth P; Ström CE; Mortusewicz O; Berglund UW; Helleday T
Cancer Res; 2020 Sep; 80(17):3530-3541. PubMed ID: 32312836
[TBL] [Abstract][Full Text] [Related]
33. MTH1 favors mesothelioma progression and mediates paracrine rescue of bystander endothelium from oxidative damage.
Magkouta SF; Pappas AG; Vaitsi PC; Agioutantis PC; Pateras IS; Moschos CA; Iliopoulou MP; Kosti CN; Loutrari HV; Gorgoulis VG; Kalomenidis IT
JCI Insight; 2020 Jun; 5(12):. PubMed ID: 32554927
[TBL] [Abstract][Full Text] [Related]
34. Investigation of MTH1 activity via mismatch-based DNA chain elongation.
Gao T; Gu S; Liu F; Li L; Wang Z; Yang J; Li G
Anal Chim Acta; 2016 Jan; 905():66-71. PubMed ID: 26755138
[TBL] [Abstract][Full Text] [Related]
35. Substrate recognition by the human MTH1 protein.
Kamiya H; Dugué L; Yakushiji H; Pochet S; Nakabeppu Y; Harashima H
Nucleic Acids Res Suppl; 2002; (2):85-6. PubMed ID: 12903117
[TBL] [Abstract][Full Text] [Related]
36. MutT homolog-1 attenuates oxidative DNA damage and delays photoreceptor cell death in inherited retinal degeneration.
Murakami Y; Ikeda Y; Yoshida N; Notomi S; Hisatomi T; Oka S; De Luca G; Yonemitsu Y; Bignami M; Nakabeppu Y; Ishibashi T
Am J Pathol; 2012 Oct; 181(4):1378-86. PubMed ID: 22841817
[TBL] [Abstract][Full Text] [Related]
37. Ectopic expression of the human MutT-type Nudix hydrolase, hMTH1, confers enhanced tolerance to oxidative stress in arabidopsis.
Yoshimura K; Ogawa T; Tsujimura M; Ishikawa K; Shigeoka S
Plant Cell Physiol; 2014 Sep; 55(9):1534-43. PubMed ID: 24928220
[TBL] [Abstract][Full Text] [Related]
38. A Chimeric ATP-Linked Nucleotide Enables Luminescence Signaling of Damage Surveillance by MTH1, a Cancer Target.
Ji D; Beharry AA; Ford JM; Kool ET
J Am Chem Soc; 2016 Jul; 138(29):9005-8. PubMed ID: 27413803
[TBL] [Abstract][Full Text] [Related]
39. Maintaining precursor pools for mitochondrial DNA replication.
Mathews CK; Song S
FASEB J; 2007 Aug; 21(10):2294-303. PubMed ID: 17403938
[TBL] [Abstract][Full Text] [Related]
40. The First Structure of an Active Mammalian dCTPase and its Complexes With Substrate Analogs and Products.
Scaletti E; Claesson M; Helleday T; Jemth AS; Stenmark P
J Mol Biol; 2020 Feb; 432(4):1126-1142. PubMed ID: 31954130
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
