265 related articles for article (PubMed ID: 27312735)
1. Phase 1 study of abemaciclib, an inhibitor of CDK 4 and 6, as a single agent for Japanese patients with advanced cancer.
Fujiwara Y; Tamura K; Kondo S; Tanabe Y; Iwasa S; Shimomura A; Kitano S; Ogasawara K; Turner PK; Mori J; Asou H; Chan EM; Yamamoto N
Cancer Chemother Pharmacol; 2016 Aug; 78(2):281-8. PubMed ID: 27312735
[TBL] [Abstract][Full Text] [Related]
2. Efficacy and Safety of Abemaciclib, an Inhibitor of CDK4 and CDK6, for Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Other Solid Tumors.
Patnaik A; Rosen LS; Tolaney SM; Tolcher AW; Goldman JW; Gandhi L; Papadopoulos KP; Beeram M; Rasco DW; Hilton JF; Nasir A; Beckmann RP; Schade AE; Fulford AD; Nguyen TS; Martinez R; Kulanthaivel P; Li LQ; Frenzel M; Cronier DM; Chan EM; Flaherty KT; Wen PY; Shapiro GI
Cancer Discov; 2016 Jul; 6(7):740-53. PubMed ID: 27217383
[TBL] [Abstract][Full Text] [Related]
3. A Population Pharmacokinetic and Pharmacodynamic Analysis of Abemaciclib in a Phase I Clinical Trial in Cancer Patients.
Tate SC; Sykes AK; Kulanthaivel P; Chan EM; Turner PK; Cronier DM
Clin Pharmacokinet; 2018 Mar; 57(3):335-344. PubMed ID: 28540640
[TBL] [Abstract][Full Text] [Related]
4. MONARCH 1, A Phase II Study of Abemaciclib, a CDK4 and CDK6 Inhibitor, as a Single Agent, in Patients with Refractory HR
Dickler MN; Tolaney SM; Rugo HS; Cortés J; Diéras V; Patt D; Wildiers H; Hudis CA; O'Shaughnessy J; Zamora E; Yardley DA; Frenzel M; Koustenis A; Baselga J
Clin Cancer Res; 2017 Sep; 23(17):5218-5224. PubMed ID: 28533223
[No Abstract] [Full Text] [Related]
5. Pharmacokinetic drug evaluation of abemaciclib for advanced breast cancer.
Robert M; Frenel JS; Bourbouloux E; Berton Rigaud D; Patsouris A; Augereau P; Gourmelon C; Campone M
Expert Opin Drug Metab Toxicol; 2019 Feb; 15(2):85-91. PubMed ID: 30577708
[TBL] [Abstract][Full Text] [Related]
6. Safety and Clinical Activity of a New Anti-PD-L1 Antibody as Monotherapy or Combined with Targeted Therapy in Advanced Solid Tumors: The PACT Phase Ia/Ib Trial.
Patnaik A; Yap TA; Chung HC; de Miguel MJ; Bang YJ; Lin CC; Su WC; Italiano A; Chow KH; Szpurka AM; Yu D; Zhao Y; Carlsen M; Schmidt S; Vangerow B; Gandhi L; Xu X; Bendell J
Clin Cancer Res; 2021 Mar; 27(5):1267-1277. PubMed ID: 33229456
[TBL] [Abstract][Full Text] [Related]
7. Abemaciclib in Combination with Single-Agent Options in Patients with Stage IV Non-Small Cell Lung Cancer: A Phase Ib Study.
Kim ES; Kelly K; Paz-Ares LG; Garrido P; Jalal S; Mahadevan D; Gutierrez M; Provencio M; Schaefer E; Shaheen M; Johnston EL; Turner PK; Kambhampati SRP; Beckmann R; Hossain A; John WJ; Goldman JW
Clin Cancer Res; 2018 Nov; 24(22):5543-5551. PubMed ID: 30082474
[No Abstract] [Full Text] [Related]
8. A Randomized Phase I Study of Abemaciclib in Chinese Patients with Advanced and/or Metastatic Cancers.
Zhang J; Yang N; Ji D; Shen W; Li W; Han R; Wang N; Tao H; Chapman SC; Sykes AK; Zhang W; Hu X
Target Oncol; 2021 Mar; 16(2):177-187. PubMed ID: 33492568
[TBL] [Abstract][Full Text] [Related]
9. Abemaciclib in combination with endocrine therapy for East Asian patients with HR+, HER2- advanced breast cancer: MONARCH 2 & 3 trials.
Toi M; Inoue K; Masuda N; Iwata H; Sohn J; Hae Park I; Im SA; Chen SC; Enatsu S; Turner PK; André VAM; Hardebeck MC; Sakaguchi S; Goetz MP; Sledge GW
Cancer Sci; 2021 Jun; 112(6):2381-2392. PubMed ID: 33686753
[TBL] [Abstract][Full Text] [Related]
10. A phase 1b study of the Notch inhibitor crenigacestat (LY3039478) in combination with other anticancer target agents (taladegib, LY3023414, or abemaciclib) in patients with advanced or metastatic solid tumors.
Azaro A; Massard C; Tap WD; Cassier PA; Merchan J; Italiano A; Anderson B; Yuen E; Yu D; Oakley G; Benhadji KA; Pant S
Invest New Drugs; 2021 Aug; 39(4):1089-1098. PubMed ID: 33686452
[TBL] [Abstract][Full Text] [Related]
11. Abemaciclib plus trastuzumab with or without fulvestrant versus trastuzumab plus standard-of-care chemotherapy in women with hormone receptor-positive, HER2-positive advanced breast cancer (monarcHER): a randomised, open-label, phase 2 trial.
Tolaney SM; Wardley AM; Zambelli S; Hilton JF; Troso-Sandoval TA; Ricci F; Im SA; Kim SB; Johnston SR; Chan A; Goel S; Catron K; Chapman SC; Price GL; Yang Z; Gainford MC; André F
Lancet Oncol; 2020 Jun; 21(6):763-775. PubMed ID: 32353342
[TBL] [Abstract][Full Text] [Related]
12. A unique CDK4/6 inhibitor: Current and future therapeutic strategies of abemaciclib.
Chong QY; Kok ZH; Bui NL; Xiang X; Wong AL; Yong WP; Sethi G; Lobie PE; Wang L; Goh BC
Pharmacol Res; 2020 Jun; 156():104686. PubMed ID: 32068118
[TBL] [Abstract][Full Text] [Related]
13. Abemaciclib: safety and effectiveness of a unique cyclin-dependent kinase inhibitor.
Gebbia V; Valerio MR; Firenze A; Vigneri P
Expert Opin Drug Saf; 2020 Aug; 19(8):945-954. PubMed ID: 32552035
[TBL] [Abstract][Full Text] [Related]
14. Comparison of treatment-related adverse events of different Cyclin-dependent kinase 4/6 inhibitors in metastatic breast cancer: A network meta-analysis.
Desnoyers A; Nadler MB; Kumar V; Saleh R; Amir E
Cancer Treat Rev; 2020 Nov; 90():102086. PubMed ID: 32861975
[TBL] [Abstract][Full Text] [Related]
15. Japanese subpopulation analysis of MONARCH 2: phase 3 study of abemaciclib plus fulvestrant for treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer that progressed on endocrine therapy.
Inoue K; Masuda N; Iwata H; Takahashi M; Ito Y; Miyoshi Y; Nakayama T; Mukai H; van der Walt JS; Mori J; Sakaguchi S; Kawaguchi T; Tanizawa Y; Llombart-Cussac A; Sledge GW; Toi M
Breast Cancer; 2021 Sep; 28(5):1038-1050. PubMed ID: 33797023
[TBL] [Abstract][Full Text] [Related]
16. Phase I trial of volasertib, a Polo-like kinase inhibitor, in Japanese patients with advanced solid tumors.
Nokihara H; Yamada Y; Fujiwara Y; Yamamoto N; Wakui H; Nakamichi S; Kitazono S; Inoue K; Harada A; Taube T; Takeuchi Y; Tamura T
Invest New Drugs; 2016 Feb; 34(1):66-74. PubMed ID: 26627079
[TBL] [Abstract][Full Text] [Related]
17. A phase 1b study of necitumumab in combination with abemaciclib in patients with stage IV non-small cell lung cancer.
Besse B; Barlesi F; Demedts I; Fuentes Pradera J; Robinet G; Gazzah A; Soldatenkova V; Frimodt-Moller B; Kim JS; Vansteenkiste J
Lung Cancer; 2019 Nov; 137():136-143. PubMed ID: 31586771
[TBL] [Abstract][Full Text] [Related]
18. Development and Application of a Mechanistic Population Modeling Approach to Describe Abemaciclib Pharmacokinetics.
Chigutsa E; Kambhampati SRP; Karen Sykes A; Posada MM; van der Walt JS; Turner PK
CPT Pharmacometrics Syst Pharmacol; 2020 Sep; 9(9):523-533. PubMed ID: 32683787
[TBL] [Abstract][Full Text] [Related]
19. Phase I dose-escalation study of buparlisib (BKM120), an oral pan-class I PI3K inhibitor, in Japanese patients with advanced solid tumors.
Ando Y; Inada-Inoue M; Mitsuma A; Yoshino T; Ohtsu A; Suenaga N; Sato M; Kakizume T; Robson M; Quadt C; Doi T
Cancer Sci; 2014 Mar; 105(3):347-53. PubMed ID: 24405565
[TBL] [Abstract][Full Text] [Related]
20. Phase 1a study of the CDK4/6 inhibitor, FCN-437c, in Chinese patients with HR + /HER2- advanced breast cancer.
Zhang J; Wang X; Wang X; Hui A; Wu Z; Tian L; Xu C; Yang Y; Zhang W; Hu X
Invest New Drugs; 2021 Dec; 39(6):1549-1558. PubMed ID: 34109484
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
