152 related articles for article (PubMed ID: 27313705)
1. A novel class of piperidones exhibit potent, selective and pro-apoptotic anti-leukemia properties.
Nunes LM; Hossain M; Varela-Ramirez A; DAS U; Ayala-Marin YM; Dimmock JR; Aguilera RJ
Oncol Lett; 2016 Jun; 11(6):3842-3848. PubMed ID: 27313705
[TBL] [Abstract][Full Text] [Related]
2. Tumour-specific cytotoxicity and structure-activity relationships of novel 1-[3-(2-methoxyethylthio)propionyl]-3,5-bis(benzylidene)-4-piperidones.
Hossain M; Das U; Umemura N; Sakagami H; Balzarini J; De Clercq E; Kawase M; Dimmock JR
Bioorg Med Chem; 2016 May; 24(10):2206-14. PubMed ID: 27073056
[TBL] [Abstract][Full Text] [Related]
3. Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones.
Contreras L; Calderon RI; Varela-Ramirez A; Zhang HY; Quan Y; Das U; Dimmock JR; Skouta R; Aguilera RJ
Cell Oncol (Dordr); 2018 Dec; 41(6):623-636. PubMed ID: 30088262
[TBL] [Abstract][Full Text] [Related]
4. Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines.
Swain RM; Contreras L; Varela-Ramirez A; Hossain M; Das U; Valenzuela CA; Penichet ML; Dimmock JR; Aguilera RJ
Invest New Drugs; 2022 Oct; 40(5):905-921. PubMed ID: 35793039
[TBL] [Abstract][Full Text] [Related]
5. Tumor-selective cytotoxicity of a novel pentadiene analogue on human leukemia/ lymphoma cells.
Santiago-Vázquez Y; Das U; Varela-Ramirez A; Baca ST; Ayala-Marin Y; Lema C; Das S; Baryyan A; Dimmock JR; Aguilera RJ
Clin Cancer Drugs; 2016; 3(2):138-146. PubMed ID: 27857884
[TBL] [Abstract][Full Text] [Related]
6. Novel Unsymmetric 3,5-Bis(benzylidene)-4-piperidones That Display Tumor-Selective Toxicity.
Chhikara A; Roayapalley PK; Sakagami H; Amano S; Satoh K; Uesawa Y; Das U; Das S; Borrego EA; Guerena CD; Hernandez CR; Aguilera RJ; Dimmock JR
Molecules; 2022 Oct; 27(19):. PubMed ID: 36235258
[TBL] [Abstract][Full Text] [Related]
7. Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms.
Contreras L; Medina S; Schiaffino Bustamante AY; Borrego EA; Valenzuela CA; Das U; Karki SS; Dimmock JR; Aguilera RJ
Pharmacol Rep; 2022 Feb; 74(1):159-174. PubMed ID: 34448104
[TBL] [Abstract][Full Text] [Related]
8. 3,5-Bis(benzylidene)-4-oxo-1-phosphonopiperidines and related diethyl esters: Potent cytotoxins with multi-drug-resistance reverting properties.
Das S; Das U; Selvakumar P; Sharma RK; Balzarini J; De Clercq E; Molnár J; Serly J; Baráth Z; Schatte G; Bandy B; Gorecki DK; Dimmock JR
ChemMedChem; 2009 Nov; 4(11):1831-40. PubMed ID: 19802855
[TBL] [Abstract][Full Text] [Related]
9. Novel hybrid molecules of 3,5-bis(benzylidene)-4-piperidones and dichloroacetic acid which demonstrate potent tumour-selective cytotoxicity.
Hossain M; Das S; Das U; Doroudi A; Zhu J; Dimmock JR
Bioorg Med Chem Lett; 2020 Feb; 30(3):126878. PubMed ID: 31864797
[TBL] [Abstract][Full Text] [Related]
10. CLEFMA-an anti-proliferative curcuminoid from structure-activity relationship studies on 3,5-bis(benzylidene)-4-piperidones.
Lagisetty P; Vilekar P; Sahoo K; Anant S; Awasthi V
Bioorg Med Chem; 2010 Aug; 18(16):6109-20. PubMed ID: 20638855
[TBL] [Abstract][Full Text] [Related]
11. 3,5-bis(phenylmethylene)-1-(N-arylmaleamoyl)-4-piperidones: a novel group of cytotoxic agents.
Dimmock JR; Jha A; Zello GA; Sharma RK; Shrivastav A; Selvakumar P; Allen TM; Santos CL; Balzarini J; De Clercq E; Manavathu EK; Stables JP
J Enzyme Inhib Med Chem; 2003 Aug; 18(4):325-32. PubMed ID: 14567547
[TBL] [Abstract][Full Text] [Related]
12. Cytotoxic N-[4-(3-aryl-3-oxo-1-propenyl)phenylcarbonyl]-3,5-bis(phenylmethylene)-4-piperidones and related compounds.
Dimmock JR; Jha A; Zello GA; Quail JW; Oloo EO; Nienaber KH; Kowalczyk ES; Allen TM; Santos CL; De Clercq E; Balzarini J; Manavathu EK; Stables JP
Eur J Med Chem; 2002 Dec; 37(12):961-72. PubMed ID: 12660021
[TBL] [Abstract][Full Text] [Related]
13. 1-[3-(2-Hydroxyethylsulfanyl)propanoyl]-3,5-bis(benzylidene)-4-piperidones: A novel cluster of P-glycoprotein dependent multidrug resistance modulators.
Das U; Pati HN; Baráth Z; Csonka Á; Molnár J; Dimmock JR
Bioorg Med Chem Lett; 2016 Feb; 26(4):1319-21. PubMed ID: 26796064
[TBL] [Abstract][Full Text] [Related]
14. CoMFA and CoMSIA studies on 1,3-bis(benzylidene)-3,4-dihydro-1H-naphthalen-2-one, 2,6-bis(benzylidene)cyclohexanone, and 3,5-bis(benzylidene)-4-piperidone series of cytotoxic compounds.
Patel MR; Dimmock JR; Talele TT
J Chem Inf Model; 2007; 47(6):2110-23. PubMed ID: 17944456
[TBL] [Abstract][Full Text] [Related]
15. Comparative QSAR Analysis of 3,5-bis (Arylidene)-4-Piperidone Derivatives: the Development of Predictive Cytotoxicity Models.
Edraki N; Das U; Hemateenejad B; Dimmock JR; Miri R
Iran J Pharm Res; 2016; 15(2):425-37. PubMed ID: 27642313
[TBL] [Abstract][Full Text] [Related]
16. 1-[4-(2-Dimethylaminoethoxy)phenylcarbonyl]-3,5-Bis(3,4,5-Trimethoxybenzylidene)- 4-Piperidone Hydrochloride and Related Compounds: Potent Cytotoxins Demonstrate Greater Toxicity to Neoplasms than Non- Malignant Cells.
Roayapalley PK; Dimmock JR; Sakagami H; Okudaira N; Sharma RK; Das U
Med Chem; 2022; 18(9):1001-1012. PubMed ID: 35319387
[TBL] [Abstract][Full Text] [Related]
17. The cytotoxic properties and preferential toxicity to tumour cells displayed by some 2,4-bis(benzylidene)-8-methyl-8-azabicyclo[3.2.1] octan-3-ones and 3,5-bis(benzylidene)-1-methyl-4-piperidones.
Pati HN; Das U; Das S; Bandy B; De Clercq E; Balzarini J; Kawase M; Sakagami H; Quail JW; Stables JP; Dimmock JR
Eur J Med Chem; 2009 Jan; 44(1):54-62. PubMed ID: 18468733
[TBL] [Abstract][Full Text] [Related]
18. Mitochondrial dysfunction contributes to the cytotoxicity of some 3,5-bis(benzylidene)-4-piperidone derivatives in colon HCT-116 cells.
Helal M; Das U; Bandy B; Islam A; Nazarali AJ; Dimmock JR
Bioorg Med Chem Lett; 2013 Feb; 23(4):1075-8. PubMed ID: 23305919
[TBL] [Abstract][Full Text] [Related]
19. Dimeric 3,5-Bis(benzylidene)-4-piperidones: Tumor-Selective Cytotoxicity and Structure-Activity Relationships.
Das S; Roayapalley PK; Sakagami H; Umemura N; Gorecki DKJ; Hossain M; Kawase M; Das U; Dimmock JR
Medicines (Basel); 2024 Jan; 11(1):. PubMed ID: 38248717
[No Abstract] [Full Text] [Related]
20. 3,5-Bis(3-alkylaminomethyl-4-hydroxybenzylidene)-4-piperidones: A Novel Class of Potent Tumor-Selective Cytotoxins.
Karki SS; Das U; Umemura N; Sakagami H; Iwamoto S; Kawase M; Balzarini J; De Clercq E; Dimmock SG; Dimmock JR
J Med Chem; 2016 Jan; 59(2):763-9. PubMed ID: 26727215
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
