BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 27317659)

  • 1. Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow Deactivation.
    Ng CA; Gravel AE; Perry MD; Arnold AA; Marcotte I; Vandenberg JI
    J Biol Chem; 2016 Aug; 291(33):17293-302. PubMed ID: 27317659
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gating mechanism of Kv11.1 (hERG) K
    de la Peña P; Domínguez P; Barros F
    Pflugers Arch; 2018 Mar; 470(3):517-536. PubMed ID: 29270671
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Voltage-dependent activation in EAG channels follows a ligand-receptor rather than a mechanical-lever mechanism.
    Malak OA; Gluhov GS; Grizel AV; Kudryashova KS; Sokolova OS; Loussouarn G
    J Biol Chem; 2019 Apr; 294(16):6506-6521. PubMed ID: 30808709
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain.
    de la Peña P; Domínguez P; Barros F
    Pflugers Arch; 2018 Jul; 470(7):1069-1085. PubMed ID: 29572566
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The S1 helix critically regulates the finely tuned gating of Kv11.1 channels.
    Phan K; Ng CA; David E; Shishmarev D; Kuchel PW; Vandenberg JI; Perry MD
    J Biol Chem; 2017 May; 292(18):7688-7705. PubMed ID: 28280240
    [TBL] [Abstract][Full Text] [Related]  

  • 6. KCNQ1 channels voltage dependence through a voltage-dependent binding of the S4-S5 linker to the pore domain.
    Choveau FS; Rodriguez N; Abderemane Ali F; Labro AJ; Rose T; Dahimène S; Boudin H; Le Hénaff C; Escande D; Snyders DJ; Charpentier F; Mérot J; Baró I; Loussouarn G
    J Biol Chem; 2011 Jan; 286(1):707-16. PubMed ID: 20940310
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes.
    Sanguinetti MC; Xu QP
    J Physiol; 1999 Feb; 514 ( Pt 3)(Pt 3):667-75. PubMed ID: 9882738
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels.
    Gianulis EC; Liu Q; Trudeau MC
    J Gen Physiol; 2013 Oct; 142(4):351-66. PubMed ID: 24043860
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regional flexibility in the S4-S5 linker regulates hERG channel closed-state stabilization.
    Hull CM; Sokolov S; Van Slyke AC; Claydon TW
    Pflugers Arch; 2014 Oct; 466(10):1911-9. PubMed ID: 24407947
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.
    Perry MD; Wong S; Ng CA; Vandenberg JI
    J Gen Physiol; 2013 Sep; 142(3):275-88. PubMed ID: 23980196
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Extracellular protons accelerate hERG channel deactivation by destabilizing voltage sensor relaxation.
    Shi YP; Thouta S; Cheng YM; Claydon TW
    J Gen Physiol; 2019 Feb; 151(2):231-246. PubMed ID: 30530765
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two mutations at different positions in the CNBH domain of the hERG channel accelerate deactivation and impair the interaction with the EAG domain.
    Kume S; Shimomura T; Tateyama M; Kubo Y
    J Physiol; 2018 Oct; 596(19):4629-4650. PubMed ID: 30086184
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutations within the S4-S5 linker alter voltage sensor constraints in hERG K+ channels.
    Van Slyke AC; Rezazadeh S; Snopkowski M; Shi P; Allard CR; Claydon TW
    Biophys J; 2010 Nov; 99(9):2841-52. PubMed ID: 21044581
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating.
    Ng CA; Perry MD; Tan PS; Hill AP; Kuchel PW; Vandenberg JI
    PLoS One; 2012; 7(2):e31640. PubMed ID: 22359612
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Fast Component of hERG Gating Charge: An Interaction between D411 in the S1 and S4 Residues.
    Dou Y; Macdonald LC; Wu Y; Fedida D
    Biophys J; 2017 Nov; 113(9):1979-1991. PubMed ID: 29117522
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular basis of slow activation of the human ether-a-go-go related gene potassium channel.
    Subbiah RN; Clarke CE; Smith DJ; Zhao J; Campbell TJ; Vandenberg JI
    J Physiol; 2004 Jul; 558(Pt 2):417-31. PubMed ID: 15181157
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stabilization of the Activated hERG Channel Voltage Sensor by Depolarization Involves the S4-S5 Linker.
    Thouta S; Hull CM; Shi YP; Sergeev V; Young J; Cheng YM; Claydon TW
    Biophys J; 2017 Jan; 112(2):300-312. PubMed ID: 28122216
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels.
    Ng CA; Phan K; Hill AP; Vandenberg JI; Perry MD
    J Biol Chem; 2014 Sep; 289(37):25822-32. PubMed ID: 25074935
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Voltage-dependent gating of HERG potassium channels.
    Cheng YM; Claydon TW
    Front Pharmacol; 2012; 3():83. PubMed ID: 22586397
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A new mechanism of voltage-dependent gating exposed by K
    Tomczak AP; Fernández-Trillo J; Bharill S; Papp F; Panyi G; Stühmer W; Isacoff EY; Pardo LA
    J Gen Physiol; 2017 May; 149(5):577-593. PubMed ID: 28360219
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.