591 related articles for article (PubMed ID: 27318118)
1. Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4(3H)-quinazolinones.
Abdel-Aziz AA; Abou-Zeid LA; ElTahir KEH; Ayyad RR; El-Sayed MA; El-Azab AS
Eur J Med Chem; 2016 Oct; 121():410-421. PubMed ID: 27318118
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis of 2,3-disubstitued 4(3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies.
Abdel-Aziz AA; Abou-Zeid LA; ElTahir KE; Mohamed MA; Abu El-Enin MA; El-Azab AS
Bioorg Med Chem; 2016 Aug; 24(16):3818-28. PubMed ID: 27344214
[TBL] [Abstract][Full Text] [Related]
3. Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study.
Moussa G; Alaaeddine R; Alaeddine LM; Nassra R; Belal ASF; Ismail A; El-Yazbi AF; Abdel-Ghany YS; Hazzaa A
Eur J Med Chem; 2018 Jan; 144():635-650. PubMed ID: 29289887
[TBL] [Abstract][Full Text] [Related]
4. 1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inflammatory and analgesic agents with an improved gastric profile: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study.
Sakr A; Kothayer H; Ibrahim SM; Baraka MM; Rezq S
Bioorg Chem; 2019 Mar; 84():76-86. PubMed ID: 30481648
[TBL] [Abstract][Full Text] [Related]
5. Design and synthesis of novel 2-phenyl-5-(1,3-diphenyl-1H-pyrazol-4-yl)-1,3,4-oxadiazoles as selective COX-2 inhibitors with potent anti-inflammatory activity.
Bansal S; Bala M; Suthar SK; Choudhary S; Bhattacharya S; Bhardwaj V; Singla S; Joseph A
Eur J Med Chem; 2014 Jun; 80():167-74. PubMed ID: 24780593
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, anti-inflammatory, analgesic and COX-1/2 inhibition activities of anilides based on 5,5-diphenylimidazolidine-2,4-dione scaffold: Molecular docking studies.
Abdel-Aziz AA; El-Azab AS; Abou-Zeid LA; ElTahir KE; Abdel-Aziz NI; Ayyad RR; Al-Obaid AM
Eur J Med Chem; 2016 Jun; 115():121-31. PubMed ID: 26999325
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and docking studies.
Abdelgawad MA; Labib MB; Ali WAM; Kamel G; Azouz AA; El-Nahass ES
Bioorg Chem; 2018 Aug; 78():103-114. PubMed ID: 29550530
[TBL] [Abstract][Full Text] [Related]
8. Synthesis, anti-inflammatory, analgesic, COX1/2-inhibitory activity, and molecular docking studies of hybrid pyrazole analogues.
Alam MJ; Alam O; Khan SA; Naim MJ; Islamuddin M; Deora GS
Drug Des Devel Ther; 2016; 10():3529-3543. PubMed ID: 27826185
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
Rao PN; Chen QH; Knaus EE
J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, biological evaluation, docking study and ulcerogenicity profiling of some novel quinoline-2-carboxamides as dual COXs/LOX inhibitors endowed with anti-inflammatory activity.
Abdelrahman MH; Youssif BGM; Abdelgawad MA; Abdelazeem AH; Ibrahim HM; Moustafa AEGA; Treamblu L; Bukhari SNA
Eur J Med Chem; 2017 Feb; 127():972-985. PubMed ID: 27837994
[TBL] [Abstract][Full Text] [Related]
11. Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: anti-inflammatory and analgesic activities.
Alanazi AM; El-Azab AS; Al-Suwaidan IA; ElTahir KE; Asiri YA; Abdel-Aziz NI; Abdel-Aziz AA
Eur J Med Chem; 2015 Mar; 92():115-23. PubMed ID: 25549551
[TBL] [Abstract][Full Text] [Related]
12. 3-methyl-2-phenyl-1-substituted-indole derivatives as indomethacin analogs: design, synthesis and biological evaluation as potential anti-inflammatory and analgesic agents.
Abdellatif KR; Lamie PF; Omar HA
J Enzyme Inhib Med Chem; 2016; 31(2):318-24. PubMed ID: 25798690
[TBL] [Abstract][Full Text] [Related]
13. Cyclic enaminone as new chemotype for selective cyclooxygenase-2 inhibitory, anti-inflammatory, and analgesic activities.
Kumar R; Saha N; Purohit P; Garg SK; Seth K; Meena VS; Dubey S; Dave K; Goyal R; Sharma SS; Banerjee UC; Chakraborti AK
Eur J Med Chem; 2019 Nov; 182():111601. PubMed ID: 31445233
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis of novel isoindoline hybrids as COX-2 inhibitors: Anti-inflammatory, analgesic activities and docking study.
Labib MB; Sharkawi SMZ; El-Daly M
Bioorg Chem; 2018 Oct; 80():70-80. PubMed ID: 30005203
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study.
Abdel-Aziz AA; ElTahir KE; Asiri YA
Eur J Med Chem; 2011 May; 46(5):1648-55. PubMed ID: 21388719
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and analgesic/anti-inflammatory evaluation of novel diarylthiazole and diarylimidazole derivatives towards selective COX-1 inhibitors with better gastric profile.
Abdelazeem AH; El-Saadi MT; Safi El-Din AG; Omar HA; El-Moghazy SM
Bioorg Med Chem; 2017 Jan; 25(2):665-676. PubMed ID: 27916468
[TBL] [Abstract][Full Text] [Related]
17. Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6-diphenyl-1,2,4-triazin-3(2H)-one derivatives bearing 5-substituted 1,3,4-oxadiazole as potential anti-inflammatory and analgesic agents.
Banerjee AG; Das N; Shengule SA; Srivastava RS; Shrivastava SK
Eur J Med Chem; 2015 Aug; 101():81-95. PubMed ID: 26117820
[TBL] [Abstract][Full Text] [Related]
18. Analogue-based design, synthesis and docking of non-steroidal anti-inflammatory agents. Part 2: methyl sulfanyl/methyl sulfonyl substituted 2,3-diaryl-2,3-dihydro-1H-quinazolin-4-ones.
Manivannan E; Chaturvedi SC
Bioorg Med Chem; 2012 Dec; 20(24):7119-27. PubMed ID: 23146282
[TBL] [Abstract][Full Text] [Related]
19. Aryl/heteroaryl Substituted Celecoxib Derivatives as COX-2 Inhibitors: Synthesis, Anti-inflammatory Activity and Molecular Docking Studies.
Madhava G; Ramana KV; Sudhana SM; Rao DS; Kumar KH; Lokanatha V; Rani AU; Raju CN
Med Chem; 2017; 13(5):484-497. PubMed ID: 28228088
[TBL] [Abstract][Full Text] [Related]
20. Synthesis of N-benzenesulfonamide-1H-pyrazoles bearing arylsulfonyl moiety: novel celecoxib analogs as potent anti-inflammatory agents.
Abdel-Aziz HA; Al-Rashood KA; ElTahir KE; Suddek GM
Eur J Med Chem; 2014 Jun; 80():416-22. PubMed ID: 24794773
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
