370 related articles for article (PubMed ID: 27318144)
1. Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.
Zhao L; Gottesdiener AJ; Parmar M; Li M; Kaminsky SM; Chiuchiolo MJ; Sondhi D; Sullivan PM; Holtzman DM; Crystal RG; Paul SM
Neurobiol Aging; 2016 Aug; 44():159-172. PubMed ID: 27318144
[TBL] [Abstract][Full Text] [Related]
2. Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease.
Dodart JC; Marr RA; Koistinaho M; Gregersen BM; Malkani S; Verma IM; Paul SM
Proc Natl Acad Sci U S A; 2005 Jan; 102(4):1211-6. PubMed ID: 15657137
[TBL] [Abstract][Full Text] [Related]
3. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice.
Hu J; Liu CC; Chen XF; Zhang YW; Xu H; Bu G
Mol Neurodegener; 2015 Mar; 10():6. PubMed ID: 25871773
[TBL] [Abstract][Full Text] [Related]
4. Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice.
Pankiewicz JE; Guridi M; Kim J; Asuni AA; Sanchez S; Sullivan PM; Holtzman DM; Sadowski MJ
Acta Neuropathol Commun; 2014 Jun; 2():75. PubMed ID: 24972680
[TBL] [Abstract][Full Text] [Related]
5. APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease.
Jackson RJ; Keiser MS; Meltzer JC; Fykstra DP; Dierksmeier SE; Hajizadeh S; Kreuzer J; Morris R; Melloni A; Nakajima T; Tecedor L; Ranum PT; Carrell E; Chen Y; Nishtar MA; Holtzman DM; Haas W; Davidson BL; Hyman BT
Mol Ther; 2024 May; 32(5):1373-1386. PubMed ID: 38504517
[TBL] [Abstract][Full Text] [Related]
6. Human apolipoprotein E2 promotes parenchymal amyloid deposition and neuronal loss in vasculotropic mutant amyloid-β protein Tg-SwDI mice.
Xu F; Vitek MP; Colton CA; Previti ML; Davis J; Van Nostrand WE
J Alzheimers Dis; 2012; 31(2):359-69. PubMed ID: 22635103
[TBL] [Abstract][Full Text] [Related]
7. Association Between Apolipoprotein E ε2 vs ε4, Age, and β-Amyloid in Adults Without Cognitive Impairment.
Insel PS; Hansson O; Mattsson-Carlgren N
JAMA Neurol; 2021 Feb; 78(2):229-235. PubMed ID: 33044487
[TBL] [Abstract][Full Text] [Related]
8. AAVrh.10-Mediated APOE2 Central Nervous System Gene Therapy for APOE4-Associated Alzheimer's Disease.
Rosenberg JB; Kaplitt MG; De BP; Chen A; Flagiello T; Salami C; Pey E; Zhao L; Ricart Arbona RJ; Monette S; Dyke JP; Ballon DJ; Kaminsky SM; Sondhi D; Petsko GA; Paul SM; Crystal RG
Hum Gene Ther Clin Dev; 2018 Mar; 29(1):24-47. PubMed ID: 29409358
[TBL] [Abstract][Full Text] [Related]
9. Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide.
Hashimoto T; Serrano-Pozo A; Hori Y; Adams KW; Takeda S; Banerji AO; Mitani A; Joyner D; Thyssen DH; Bacskai BJ; Frosch MP; Spires-Jones TL; Finn MB; Holtzman DM; Hyman BT
J Neurosci; 2012 Oct; 32(43):15181-92. PubMed ID: 23100439
[TBL] [Abstract][Full Text] [Related]
10. Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer's Disease Prevention and Early Intervention.
Keeney JT; Ibrahimi S; Zhao L
J Alzheimers Dis; 2015; 48(2):411-24. PubMed ID: 26402005
[TBL] [Abstract][Full Text] [Related]
11. APOE effects on regional tau in preclinical Alzheimer's disease.
Young CB; Johns E; Kennedy G; Belloy ME; Insel PS; Greicius MD; Sperling RA; Johnson KA; Poston KL; Mormino EC; ;
Mol Neurodegener; 2023 Jan; 18(1):1. PubMed ID: 36597122
[TBL] [Abstract][Full Text] [Related]
12. APOE modulates the effect of estrogen therapy on Aβ accumulation EFAD-Tg mice.
Kunzler J; Youmans KL; Yu C; Ladu MJ; Tai LM
Neurosci Lett; 2014 Feb; 560():131-6. PubMed ID: 24368217
[TBL] [Abstract][Full Text] [Related]
13. Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology.
Baum L; Chen L; Ng HK; Pang CP
Microsc Res Tech; 2000 Aug; 50(4):278-81. PubMed ID: 10936880
[TBL] [Abstract][Full Text] [Related]
14. Intramuscular delivery of p75NTR ectodomain by an AAV vector attenuates cognitive deficits and Alzheimer's disease-like pathologies in APP/PS1 transgenic mice.
Wang QH; Wang YR; Zhang T; Jiao SS; Liu YH; Zeng F; Li J; Yao XQ; Zhou HD; Zhou XF; Wang YJ
J Neurochem; 2016 Jul; 138(1):163-73. PubMed ID: 26991827
[TBL] [Abstract][Full Text] [Related]
15. APOE genotype results in differential effects on the peripheral clearance of amyloid-beta42 in APOE knock-in and knock-out mice.
Sharman MJ; Morici M; Hone E; Berger T; Taddei K; Martins IJ; Lim WL; Singh S; Wenk MR; Ghiso J; Buxbaum JD; Gandy S; Martins RN
J Alzheimers Dis; 2010; 21(2):403-9. PubMed ID: 20555142
[TBL] [Abstract][Full Text] [Related]
16. Anti-Abeta single-chain antibody delivery via adeno-associated virus for treatment of Alzheimer's disease.
Fukuchi K; Tahara K; Kim HD; Maxwell JA; Lewis TL; Accavitti-Loper MA; Kim H; Ponnazhagan S; Lalonde R
Neurobiol Dis; 2006 Sep; 23(3):502-11. PubMed ID: 16766200
[TBL] [Abstract][Full Text] [Related]
17. APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
Tachibana M; Holm ML; Liu CC; Shinohara M; Aikawa T; Oue H; Yamazaki Y; Martens YA; Murray ME; Sullivan PM; Weyer K; Glerup S; Dickson DW; Bu G; Kanekiyo T
J Clin Invest; 2019 Mar; 129(3):1272-1277. PubMed ID: 30741718
[TBL] [Abstract][Full Text] [Related]
18. Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
Castellano JM; Kim J; Stewart FR; Jiang H; DeMattos RB; Patterson BW; Fagan AM; Morris JC; Mawuenyega KG; Cruchaga C; Goate AM; Bales KR; Paul SM; Bateman RJ; Holtzman DM
Sci Transl Med; 2011 Jun; 3(89):89ra57. PubMed ID: 21715678
[TBL] [Abstract][Full Text] [Related]
19. Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex.
Arold S; Sullivan P; Bilousova T; Teng E; Miller CA; Poon WW; Vinters HV; Cornwell LB; Saing T; Cole GM; Gylys KH
Acta Neuropathol; 2012 Jan; 123(1):39-52. PubMed ID: 22020632
[TBL] [Abstract][Full Text] [Related]
20. Apolipoprotein E isoform-dependent effects on the processing of Alzheimer's amyloid-β.
Chai AB; Lam HHJ; Kockx M; Gelissen IC
Biochim Biophys Acta Mol Cell Biol Lipids; 2021 Sep; 1866(9):158980. PubMed ID: 34044125
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
