173 related articles for article (PubMed ID: 27320963)
1. What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse?
Wagmann L; Meyer MR; Maurer HH
Toxicol Lett; 2016 Sep; 258():55-70. PubMed ID: 27320963
[TBL] [Abstract][Full Text] [Related]
2. Cyclic conversion of the novel Src kinase inhibitor [7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine (TG100435) and Its N-oxide metabolite by flavin-containing monoxygenases and cytochrome P450 reductase.
Kousba A; Soll R; Yee S; Martin M
Drug Metab Dispos; 2007 Dec; 35(12):2242-51. PubMed ID: 17881660
[TBL] [Abstract][Full Text] [Related]
3. Relative contribution of cytochromes P-450 and flavin-containing monoxygenases to the metabolism of albendazole by human liver microsomes.
Rawden HC; Kokwaro GO; Ward SA; Edwards G
Br J Clin Pharmacol; 2000 Apr; 49(4):313-22. PubMed ID: 10759686
[TBL] [Abstract][Full Text] [Related]
4. Benzydamine N-oxygenation as an index for flavin-containing monooxygenase activity and benzydamine N-demethylation by cytochrome P450 enzymes in liver microsomes from rats, dogs, monkeys, and humans.
Taniguchi-Takizawa T; Shimizu M; Kume T; Yamazaki H
Drug Metab Pharmacokinet; 2015 Feb; 30(1):64-9. PubMed ID: 25760531
[TBL] [Abstract][Full Text] [Related]
5. Flavin monooxygenases, FMO1 and FMO3, not cytochrome P450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells.
Fedejko-Kap B; Niemira M; Radominska-Pandya A; Mazerska Z
Xenobiotica; 2011 Dec; 41(12):1044-55. PubMed ID: 21859392
[TBL] [Abstract][Full Text] [Related]
6. Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3.
Lang DH; Yeung CK; Peter RM; Ibarra C; Gasser R; Itagaki K; Philpot RM; Rettie AE
Biochem Pharmacol; 1998 Oct; 56(8):1005-12. PubMed ID: 9776311
[TBL] [Abstract][Full Text] [Related]
7. Benzydamine N-oxidation as an index reaction reflecting FMO activity in human liver microsomes and impact of FMO3 polymorphisms on enzyme activity.
Störmer E; Roots I; Brockmöller J
Br J Clin Pharmacol; 2000 Dec; 50(6):553-61. PubMed ID: 11136294
[TBL] [Abstract][Full Text] [Related]
8. Hepatic Flavin-Containing Monooxygenase 3 Enzyme Suppressed by Type 1 Allergy-Produced Nitric Oxide.
Tanino T; Bando T; Komada A; Nojiri Y; Okada Y; Ueda Y; Sakurai E
Drug Metab Dispos; 2017 Nov; 45(11):1189-1196. PubMed ID: 28760731
[TBL] [Abstract][Full Text] [Related]
9. In vitro evaluation of potential in vivo probes for human flavin-containing monooxygenase (FMO): metabolism of benzydamine and caffeine by FMO and P450 isoforms.
Lang DH; Rettie AE
Br J Clin Pharmacol; 2000 Oct; 50(4):311-4. PubMed ID: 11012553
[TBL] [Abstract][Full Text] [Related]
10. Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450.
Chung WG; Park CS; Roh HK; Lee WK; Cha YN
Jpn J Pharmacol; 2000 Oct; 84(2):213-20. PubMed ID: 11128045
[TBL] [Abstract][Full Text] [Related]
11. Activation and deactivation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by cytochrome P450 enzymes and flavin-containing monooxygenases in common marmosets (Callithrix jacchus).
Uehara S; Uno Y; Inoue T; Murayama N; Shimizu M; Sasaki E; Yamazaki H
Drug Metab Dispos; 2015 May; 43(5):735-42. PubMed ID: 25735838
[TBL] [Abstract][Full Text] [Related]
12. S-oxidation of S-methyl-esonarimod by flavin-containing monooxygenases in human liver microsomes.
Ohmi N; Yoshida H; Endo H; Hasegawa M; Akimoto M; Higuchi S
Xenobiotica; 2003 Dec; 33(12):1221-31. PubMed ID: 14742144
[TBL] [Abstract][Full Text] [Related]
13. Flavin-containing monooxygenase activity can be inhibited by nitric oxide-mediated S-nitrosylation.
Ryu SD; Yi HG; Cha YN; Kang JH; Kang JS; Jeon YC; Park HK; Yu TM; Lee JN; Park CS
Life Sci; 2004 Oct; 75(21):2559-72. PubMed ID: 15363661
[TBL] [Abstract][Full Text] [Related]
14. The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthion.
Leoni C; Buratti FM; Testai E
Toxicol Appl Pharmacol; 2008 Dec; 233(2):343-52. PubMed ID: 18845175
[TBL] [Abstract][Full Text] [Related]
15. Assessment of the N-oxidation of deprenyl, methamphetamine, and amphetamine enantiomers by chiral capillary electrophoresis: an in vitro metabolism study.
Szöko E; Tábi T; Borbás T; Dalmadi B; Tihanyi K; Magyar K
Electrophoresis; 2004 Aug; 25(16):2866-75. PubMed ID: 15352021
[TBL] [Abstract][Full Text] [Related]
16. Application of the relative activity factor approach in scaling from heterologously expressed cytochromes p450 to human liver microsomes: studies on amitriptyline as a model substrate.
Venkatakrishnan K; von Moltke LL; Greenblatt DJ
J Pharmacol Exp Ther; 2001 Apr; 297(1):326-37. PubMed ID: 11259560
[TBL] [Abstract][Full Text] [Related]
17. In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism.
Yu J; Brown DG; Burdette D
Drug Metab Dispos; 2010 Oct; 38(10):1767-78. PubMed ID: 20595377
[TBL] [Abstract][Full Text] [Related]
18. Flavin-containing monooxygenase 1-catalysed N,N-dimethylamphetamine N-oxidation.
Lee SK; Kang MJ; Jin C; In MK; Kim DH; Yoo HH
Xenobiotica; 2009 Sep; 39(9):680-6. PubMed ID: 19552509
[TBL] [Abstract][Full Text] [Related]
19. Roles of FMO and CYP450 in the metabolism in human liver microsomes of S-methyl-N,N-diethyldithiocarbamate, a disulfiram metabolite.
Pike MG; Martin YN; Mays DC; Benson LM; Naylor S; Lipsky JJ
Alcohol Clin Exp Res; 1999 Jul; 23(7):1173-9. PubMed ID: 10443982
[TBL] [Abstract][Full Text] [Related]
20. Trimethylamine N-oxygenation in cynomolgus macaques genotyped for flavin-containing monooxygenase 3 (FMO3).
Shimizu M; Uno Y; Utoh M; Yamazaki H
Drug Metab Pharmacokinet; 2020 Dec; 35(6):571-573. PubMed ID: 32967780
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]