BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

628 related articles for article (PubMed ID: 27325232)

  • 1. Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.
    Gómez-Lechón MJ; Tolosa L
    Arch Toxicol; 2016 Sep; 90(9):2049-2061. PubMed ID: 27325232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prediction of Drug-Induced Liver Injury in Micropatterned Co-cultures Containing iPSC-Derived Human Hepatocytes.
    Ware BR; Berger DR; Khetani SR
    Toxicol Sci; 2015 Jun; 145(2):252-62. PubMed ID: 25716675
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prediction of drug-induced immune-mediated hepatotoxicity using hepatocyte-like cells derived from human embryonic stem cells.
    Kim DE; Jang MJ; Kim YR; Lee JY; Cho EB; Kim E; Kim Y; Kim MY; Jeong WI; Kim S; Han YM; Lee SH
    Toxicology; 2017 Jul; 387():1-9. PubMed ID: 28645575
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing.
    Tolosa L; Gómez-Lechón MJ; López S; Guzmán C; Castell JV; Donato MT; Jover R
    Toxicol Sci; 2016 Jul; 152(1):214-29. PubMed ID: 27208088
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Morphological and Functional Characterization and Assessment of iPSC-Derived Hepatocytes for In Vitro Toxicity Testing.
    Lu J; Einhorn S; Venkatarangan L; Miller M; Mann DA; Watkins PB; LeCluyse E
    Toxicol Sci; 2015 Sep; 147(1):39-54. PubMed ID: 26092927
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stem-cell derived hepatocyte-like cells for the assessment of drug-induced liver injury.
    Donato MT; Tolosa L
    Differentiation; 2019; 106():15-22. PubMed ID: 30844688
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Advances in Engineered Liver Models for Investigating Drug-Induced Liver Injury.
    Lin C; Khetani SR
    Biomed Res Int; 2016; 2016():1829148. PubMed ID: 27725933
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thinking outside the liver: induced pluripotent stem cells for hepatic applications.
    Subba Rao M; Sasikala M; Nageshwar Reddy D
    World J Gastroenterol; 2013 Jun; 19(22):3385-96. PubMed ID: 23801830
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pluripotent stem cell derived hepatocyte like cells and their potential in toxicity screening.
    Greenhough S; Medine CN; Hay DC
    Toxicology; 2010 Dec; 278(3):250-5. PubMed ID: 20674645
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Direct and indirect contribution of human embryonic stem cell-derived hepatocyte-like cells to liver repair in mice.
    Woo DH; Kim SK; Lim HJ; Heo J; Park HS; Kang GY; Kim SE; You HJ; Hoeppner DJ; Kim Y; Kwon H; Choi TH; Lee JH; Hong SH; Song KW; Ahn EK; Chenoweth JG; Tesar PJ; McKay RD; Kim JH
    Gastroenterology; 2012 Mar; 142(3):602-11. PubMed ID: 22138358
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity.
    Choudhury Y; Toh YC; Xing J; Qu Y; Poh J; Li H; Tan HS; Kanesvaran R; Yu H; Tan MH
    Sci Rep; 2017 Jan; 7():41238. PubMed ID: 28120901
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The application of omics-based human liver platforms for investigating the mechanism of drug-induced hepatotoxicity in vitro.
    Jiang J; Pieterman CD; Ertaylan G; Peeters RLM; de Kok TMCM
    Arch Toxicol; 2019 Nov; 93(11):3067-3098. PubMed ID: 31586243
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evolution of Novel 3D Culture Systems for Studies of Human Liver Function and Assessments of the Hepatotoxicity of Drugs and Drug Candidates.
    Andersson TB
    Basic Clin Pharmacol Toxicol; 2017 Oct; 121(4):234-238. PubMed ID: 28470941
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Toxicological applications of human induced pluripotent stem cell-derived hepatocyte-like cells: an updated review.
    Gao X; Yourick JJ; Sprando RL
    J Toxicol Sci; 2023; 48(8):441-456. PubMed ID: 37532578
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prediction of hepatotoxicity for drugs using human pluripotent stem cell-derived hepatocytes.
    Kim JH; Wang M; Lee J; Park HJ; Han C; Hong HS; Kim JS; An GH; Park K; Park HK; Zhu SF; Sun XB; Kim JH; Woo DH
    Cell Biol Toxicol; 2018 Feb; 34(1):51-64. PubMed ID: 28382404
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.
    Heslop JA; Kia R; Pridgeon CS; Sison-Young RL; Liloglou T; Elmasry M; Fenwick SW; Mills JS; Kitteringham NR; Goldring CE; Park BK
    Stem Cells Transl Med; 2017 May; 6(5):1321-1331. PubMed ID: 28456008
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 marketed drugs with known liver injury profiles.
    Zhang J; Doshi U; Suzuki A; Chang CW; Borlak J; Li AP; Tong W
    Chem Biol Interact; 2016 Aug; 255():3-11. PubMed ID: 26581450
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MicroRNA-122: a novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity.
    Kia R; Kelly L; Sison-Young RL; Zhang F; Pridgeon CS; Heslop JA; Metcalfe P; Kitteringham NR; Baxter M; Harrison S; Hanley NA; Burke ZD; Storm MP; Welham MJ; Tosh D; Küppers-Munther B; Edsbagge J; Starkey Lewis PJ; Bonner F; Harpur E; Sidaway J; Bowes J; Fenwick SW; Malik H; Goldring CE; Park BK
    Toxicol Sci; 2015 Mar; 144(1):173-85. PubMed ID: 25527335
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell-Derived Organoids.
    Shinozawa T; Kimura M; Cai Y; Saiki N; Yoneyama Y; Ouchi R; Koike H; Maezawa M; Zhang RR; Dunn A; Ferguson A; Togo S; Lewis K; Thompson WL; Asai A; Takebe T
    Gastroenterology; 2021 Feb; 160(3):831-846.e10. PubMed ID: 33039464
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Toward preclinical predictive drug testing for metabolism and hepatotoxicity by using in vitro models derived from human embryonic stem cells and human cell lines - a report on the Vitrocellomics EU-project.
    Mandenius CF; Andersson TB; Alves PM; Batzl-Hartmann C; Björquist P; Carrondo MJ; Chesne C; Coecke S; Edsbagge J; Fredriksson JM; Gerlach JC; Heinzle E; Ingelman-Sundberg M; Johansson I; Küppers-Munther B; Müller-Vieira U; Noor F; Zeilinger K
    Altern Lab Anim; 2011 May; 39(2):147-71. PubMed ID: 21639679
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.