These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

270 related articles for article (PubMed ID: 27325698)

  • 1. Oligomers of Amyloid β Prevent Physiological Activation of the Cellular Prion Protein-Metabotropic Glutamate Receptor 5 Complex by Glutamate in Alzheimer Disease.
    Haas LT; Strittmatter SM
    J Biol Chem; 2016 Aug; 291(33):17112-21. PubMed ID: 27325698
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of Amyloid β Oligomer Binding to Neurons and Neurotoxicity by the Prion Protein-mGluR5 Complex.
    Beraldo FH; Ostapchenko VG; Caetano FA; Guimaraes AL; Ferretti GD; Daude N; Bertram L; Nogueira KO; Silva JL; Westaway D; Cashman NR; Martins VR; Prado VF; Prado MA
    J Biol Chem; 2016 Oct; 291(42):21945-21955. PubMed ID: 27563063
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Therapeutic molecules and endogenous ligands regulate the interaction between brain cellular prion protein (PrPC) and metabotropic glutamate receptor 5 (mGluR5).
    Haas LT; Kostylev MA; Strittmatter SM
    J Biol Chem; 2014 Oct; 289(41):28460-77. PubMed ID: 25148681
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein.
    Um JW; Kaufman AC; Kostylev M; Heiss JK; Stagi M; Takahashi H; Kerrisk ME; Vortmeyer A; Wisniewski T; Koleske AJ; Gunther EC; Nygaard HB; Strittmatter SM
    Neuron; 2013 Sep; 79(5):887-902. PubMed ID: 24012003
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes.
    Haas LT; Salazar SV; Smith LM; Zhao HR; Cox TO; Herber CS; Degnan AP; Balakrishnan A; Macor JE; Albright CF; Strittmatter SM
    Cell Rep; 2017 Jul; 20(1):76-88. PubMed ID: 28683325
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Peptide aptamer targeting Aβ-PrP-Fyn axis reduces Alzheimer's disease pathologies in 5XFAD transgenic mouse model.
    Ali T; Klein AN; Vu A; Arifin MI; Hannaoui S; Gilch S
    Cell Mol Life Sci; 2023 May; 80(6):139. PubMed ID: 37149826
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's disease.
    Haas LT; Salazar SV; Kostylev MA; Um JW; Kaufman AC; Strittmatter SM
    Brain; 2016 Feb; 139(Pt 2):526-46. PubMed ID: 26667279
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prion-Protein-interacting Amyloid-β Oligomers of High Molecular Weight Are Tightly Correlated with Memory Impairment in Multiple Alzheimer Mouse Models.
    Kostylev MA; Kaufman AC; Nygaard HB; Patel P; Haas LT; Gunther EC; Vortmeyer A; Strittmatter SM
    J Biol Chem; 2015 Jul; 290(28):17415-38. PubMed ID: 26018073
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synaptotoxic Signaling by Amyloid Beta Oligomers in Alzheimer's Disease Through Prion Protein and mGluR5.
    Brody AH; Strittmatter SM
    Adv Pharmacol; 2018; 82():293-323. PubMed ID: 29413525
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cellular prion protein as a receptor for amyloid-β oligomers in Alzheimer's disease.
    Salazar SV; Strittmatter SM
    Biochem Biophys Res Commun; 2017 Feb; 483(4):1143-1147. PubMed ID: 27639648
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Systematic and standardized comparison of reported amyloid-β receptors for sufficiency, affinity, and Alzheimer's disease relevance.
    Smith LM; Kostylev MA; Lee S; Strittmatter SM
    J Biol Chem; 2019 Apr; 294(15):6042-6053. PubMed ID: 30787106
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ca(2+)/calmodulin-dependent protein kinase II interacts with group I metabotropic glutamate and facilitates receptor endocytosis and ERK1/2 signaling: role of β-amyloid.
    Raka F; Di Sebastiano AR; Kulhawy SC; Ribeiro FM; Godin CM; Caetano FA; Angers S; Ferguson SS
    Mol Brain; 2015 Mar; 8():21. PubMed ID: 25885040
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The prion protein ligand, stress-inducible phosphoprotein 1, regulates amyloid-β oligomer toxicity.
    Ostapchenko VG; Beraldo FH; Mohammad AH; Xie YF; Hirata PH; Magalhaes AC; Lamour G; Li H; Maciejewski A; Belrose JC; Teixeira BL; Fahnestock M; Ferreira ST; Cashman NR; Hajj GN; Jackson MF; Choy WY; MacDonald JF; Martins VR; Prado VF; Prado MA
    J Neurosci; 2013 Oct; 33(42):16552-64. PubMed ID: 24133259
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Liquid and Hydrogel Phases of PrP
    Kostylev MA; Tuttle MD; Lee S; Klein LE; Takahashi H; Cox TO; Gunther EC; Zilm KW; Strittmatter SM
    Mol Cell; 2018 Nov; 72(3):426-443.e12. PubMed ID: 30401430
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prions and Neurodegenerative Diseases: A Focus on Alzheimer's Disease.
    Crestini A; Santilli F; Martellucci S; Carbone E; Sorice M; Piscopo P; Mattei V
    J Alzheimers Dis; 2022; 85(2):503-518. PubMed ID: 34864675
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Link of the Prion Protein with Ca
    De Mario A; Peggion C; Massimino ML; Norante RP; Zulian A; Bertoli A; Sorgato MC
    Int J Mol Sci; 2019 Sep; 20(18):. PubMed ID: 31546771
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons.
    Um JW; Nygaard HB; Heiss JK; Kostylev MA; Stagi M; Vortmeyer A; Wisniewski T; Gunther EC; Strittmatter SM
    Nat Neurosci; 2012 Sep; 15(9):1227-35. PubMed ID: 22820466
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aβ oligomers induce pathophysiological mGluR5 signaling in Alzheimer's disease model mice in a sex-selective manner.
    Abd-Elrahman KS; Albaker A; de Souza JM; Ribeiro FM; Schlossmacher MG; Tiberi M; Hamilton A; Ferguson SSG
    Sci Signal; 2020 Dec; 13(662):. PubMed ID: 33323410
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers.
    Jarosz-Griffiths HH; Corbett NJ; Rowland HA; Fisher K; Jones AC; Baron J; Howell GJ; Cowley SA; Chintawar S; Cader MZ; Kellett KAB; Hooper NM
    J Biol Chem; 2019 Apr; 294(17):7085-7097. PubMed ID: 30872401
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of group-I metabotropic glutamate receptors protects against prion toxicity.
    Goniotaki D; Lakkaraju AKK; Shrivastava AN; Bakirci P; Sorce S; Senatore A; Marpakwar R; Hornemann S; Gasparini F; Triller A; Aguzzi A
    PLoS Pathog; 2017 Nov; 13(11):e1006733. PubMed ID: 29176838
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.