209 related articles for article (PubMed ID: 27327137)
1. Pharmacokinetics and Pharmacodynamics of a 13-mer LNA-inhibitor-miR-221 in Mice and Non-human Primates.
Gallo Cantafio ME; Nielsen BS; Mignogna C; Arbitrio M; Botta C; Frandsen NM; Rolfo C; Tagliaferri P; Tassone P; Di Martino MT
Mol Ther Nucleic Acids; 2016 Jun; 5(6):. PubMed ID: 27327137
[TBL] [Abstract][Full Text] [Related]
2. In vitro and in vivo activity of a novel locked nucleic acid (LNA)-inhibitor-miR-221 against multiple myeloma cells.
Di Martino MT; Gullà A; Gallo Cantafio ME; Altomare E; Amodio N; Leone E; Morelli E; Lio SG; Caracciolo D; Rossi M; Frandsen NM; Tagliaferri P; Tassone P
PLoS One; 2014; 9(2):e89659. PubMed ID: 24586944
[TBL] [Abstract][Full Text] [Related]
3. Safety and activity of the first-in-class locked nucleic acid (LNA) miR-221 selective inhibitor in refractory advanced cancer patients: a first-in-human, phase 1, open-label, dose-escalation study.
Tassone P; Di Martino MT; Arbitrio M; Fiorillo L; Staropoli N; Ciliberto D; Cordua A; Scionti F; Bertucci B; Salvino A; Lopreiato M; Thunarf F; Cuomo O; Zito MC; De Fina MR; Brescia A; Gualtieri S; Riillo C; Manti F; Caracciolo D; Barbieri V; Di Paola ED; Di Francesco AE; Tagliaferri P
J Hematol Oncol; 2023 Jun; 16(1):68. PubMed ID: 37365583
[TBL] [Abstract][Full Text] [Related]
4. Dose-Finding Study and Pharmacokinetics Profile of the Novel 13-Mer Antisense miR-221 Inhibitor in Sprague-Dawley Rats.
Di Martino MT; Arbitrio M; Caracciolo D; Scionti F; Tagliaferri P; Tassone P
Mol Ther Nucleic Acids; 2020 Jun; 20():73-85. PubMed ID: 32146420
[TBL] [Abstract][Full Text] [Related]
5. Development and validation of a bioanalytical method for quantification of LNA-i-miR-221, a 13-mer oligonucleotide, in rat plasma using LC-MS/MS.
Franzoni S; Vezzelli A; Turtoro A; Solazzo L; Greco A; Tassone P; Di Martino MT; Breda M
J Pharm Biomed Anal; 2018 Feb; 150():300-307. PubMed ID: 29268195
[TBL] [Abstract][Full Text] [Related]
6. Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function.
Bernardo BC; Gao XM; Winbanks CE; Boey EJ; Tham YK; Kiriazis H; Gregorevic P; Obad S; Kauppinen S; Du XJ; Lin RC; McMullen JR
Proc Natl Acad Sci U S A; 2012 Oct; 109(43):17615-20. PubMed ID: 23047694
[TBL] [Abstract][Full Text] [Related]
7. Allometric Scaling Approaches for Predicting Human Pharmacokinetic of a Locked Nucleic Acid Oligonucleotide Targeting Cancer-Associated miR-221.
Di Martino MT; Arbitrio M; Fonsi M; Erratico CA; Scionti F; Caracciolo D; Tagliaferri P; Tassone P
Cancers (Basel); 2019 Dec; 12(1):. PubMed ID: 31861748
[No Abstract] [Full Text] [Related]
8. LNA-mediated microRNA silencing in non-human primates.
Elmén J; Lindow M; Schütz S; Lawrence M; Petri A; Obad S; Lindholm M; Hedtjärn M; Hansen HF; Berger U; Gullans S; Kearney P; Sarnow P; Straarup EM; Kauppinen S
Nature; 2008 Apr; 452(7189):896-9. PubMed ID: 18368051
[TBL] [Abstract][Full Text] [Related]
9. Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates.
Straarup EM; Fisker N; Hedtjärn M; Lindholm MW; Rosenbohm C; Aarup V; Hansen HF; Ørum H; Hansen JB; Koch T
Nucleic Acids Res; 2010 Nov; 38(20):7100-11. PubMed ID: 20615897
[TBL] [Abstract][Full Text] [Related]
10. PEI-complexed LNA antiseeds as miRNA inhibitors.
Thomas M; Lange-Grünweller K; Dayyoub E; Bakowsky U; Weirauch U; Aigner A; Hartmann RK; Grünweller A
RNA Biol; 2012 Aug; 9(8):1088-98. PubMed ID: 22894918
[TBL] [Abstract][Full Text] [Related]
11. Pharmacological Inhibition of miR-130 Family Suppresses Bladder Tumor Growth by Targeting Various Oncogenic Pathways via PTPN1.
Monoe Y; Jingushi K; Kawase A; Hirono T; Hirose R; Nakatsuji Y; Kitae K; Ueda Y; Hase H; Abe Y; Adachi J; Tomonaga T; Tsujikawa K
Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33947152
[TBL] [Abstract][Full Text] [Related]
12. Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver.
Elmén J; Lindow M; Silahtaroglu A; Bak M; Christensen M; Lind-Thomsen A; Hedtjärn M; Hansen JB; Hansen HF; Straarup EM; McCullagh K; Kearney P; Kauppinen S
Nucleic Acids Res; 2008 Mar; 36(4):1153-62. PubMed ID: 18158304
[TBL] [Abstract][Full Text] [Related]
13. In vitro and in vivo activity of miR-92a-Locked Nucleic Acid (LNA)-Inhibitor against endometrial cancer.
Torres A; Kozak J; Korolczuk A; Wdowiak P; Domańska-Glonek E; Maciejewski R; Torres K
BMC Cancer; 2016 Oct; 16(1):822. PubMed ID: 27782822
[TBL] [Abstract][Full Text] [Related]
14. Development and validation of bioanalytical methods for LNA-i-miR-221 quantification in human plasma and urine by LC-MS/MS.
Franzoni S; Morbioli L; Turtoro A; Solazzo L; Greco A; Arbitrio M; Tagliaferri P; Tassone P; Di Martino MT; Breda M
J Pharm Biomed Anal; 2020 Sep; 188():113451. PubMed ID: 32659676
[TBL] [Abstract][Full Text] [Related]
15. Locked nucleic acid-inhibitor of miR-205 decreases endometrial cancer cells proliferation in vitro and in vivo.
Torres A; Kozak J; Korolczuk A; Rycak D; Wdowiak P; Maciejewski R; Torres K
Oncotarget; 2016 Nov; 7(45):73651-73663. PubMed ID: 27655663
[TBL] [Abstract][Full Text] [Related]
16. LNA-anti-miR-150 ameliorated kidney injury of lupus nephritis by inhibiting renal fibrosis and macrophage infiltration.
Luan J; Fu J; Chen C; Jiao C; Kong W; Zhang Y; Chang Q; Wang Y; Li D; Illei GG; Kopp JB; Pi J; Zhou H
Arthritis Res Ther; 2019 Dec; 21(1):276. PubMed ID: 31829247
[TBL] [Abstract][Full Text] [Related]
17. A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells.
Gullà A; Di Martino MT; Gallo Cantafio ME; Morelli E; Amodio N; Botta C; Pitari MR; Lio SG; Britti D; Stamato MA; Hideshima T; Munshi NC; Anderson KC; Tagliaferri P; Tassone P
Clin Cancer Res; 2016 Mar; 22(5):1222-33. PubMed ID: 26527748
[TBL] [Abstract][Full Text] [Related]
18. MicroRNA-361-3p is a potent therapeutic target for oral squamous cell carcinoma.
Ogawa H; Nakashiro KI; Tokuzen N; Kuribayashi N; Goda H; Uchida D
Cancer Sci; 2020 May; 111(5):1645-1651. PubMed ID: 32086979
[TBL] [Abstract][Full Text] [Related]
19. Locked nucleic acid anti-miR-21 inhibits cell growth and invasive behaviors of a colorectal adenocarcinoma cell line: LNA-anti-miR as a novel approach.
Nedaeinia R; Sharifi M; Avan A; Kazemi M; Rafiee L; Ghayour-Mobarhan M; Salehi R
Cancer Gene Ther; 2016 Aug; 23(8):246-53. PubMed ID: 27364574
[TBL] [Abstract][Full Text] [Related]
20. Chemical Synthesis of LNA-mCTP and its application for MicroRNA detection.
Kore AR; Hodeib M; Hu Z
Nucleosides Nucleotides Nucleic Acids; 2008 Jan; 27(1):1-17. PubMed ID: 18188765
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
