These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
215 related articles for article (PubMed ID: 27334428)
1. Metformin and gefitinib cooperate to inhibit bladder cancer growth via both AMPK and EGFR pathways joining at Akt and Erk. Peng M; Huang Y; Tao T; Peng CY; Su Q; Xu W; Darko KO; Tao X; Yang X Sci Rep; 2016 Jun; 6():28611. PubMed ID: 27334428 [TBL] [Abstract][Full Text] [Related]
2. Evaluation of the therapeutic potential of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in preclinical models of bladder cancer. Dominguez-Escrig JL; Kelly JD; Neal DE; King SM; Davies BR Clin Cancer Res; 2004 Jul; 10(14):4874-84. PubMed ID: 15269164 [TBL] [Abstract][Full Text] [Related]
3. Synergistic effects of metformin treatment in combination with gefitinib, a selective EGFR tyrosine kinase inhibitor, in LKB1 wild-type NSCLC cell lines. Morgillo F; Sasso FC; Della Corte CM; Vitagliano D; D'Aiuto E; Troiani T; Martinelli E; De Vita F; Orditura M; De Palma R; Ciardiello F Clin Cancer Res; 2013 Jul; 19(13):3508-19. PubMed ID: 23695170 [TBL] [Abstract][Full Text] [Related]
4. Uncoupling between epidermal growth factor receptor and downstream signals defines resistance to the antiproliferative effect of Gefitinib in bladder cancer cells. Kassouf W; Dinney CP; Brown G; McConkey DJ; Diehl AJ; Bar-Eli M; Adam L Cancer Res; 2005 Nov; 65(22):10524-35. PubMed ID: 16288045 [TBL] [Abstract][Full Text] [Related]
5. Combined epidermal growth factor receptor targeting with the tyrosine kinase inhibitor gefitinib (ZD1839) and the monoclonal antibody cetuximab (IMC-C225): superiority over single-agent receptor targeting. Matar P; Rojo F; Cassia R; Moreno-Bueno G; Di Cosimo S; Tabernero J; Guzmán M; Rodriguez S; Arribas J; Palacios J; Baselga J Clin Cancer Res; 2004 Oct; 10(19):6487-501. PubMed ID: 15475436 [TBL] [Abstract][Full Text] [Related]
6. High efficacy of intravesical treatment of metformin on bladder cancer in preclinical model. Peng M; Su Q; Zeng Q; Li L; Liu Z; Xue L; Cheng Y; Huang Y; Tao T; Lv H; Li X; Tao X; Guo P; Chen AF; Yang X Oncotarget; 2016 Feb; 7(8):9102-17. PubMed ID: 26802022 [TBL] [Abstract][Full Text] [Related]
7. The MEK/MAPK pathway is involved in the resistance of breast cancer cells to the EGFR tyrosine kinase inhibitor gefitinib. Normanno N; De Luca A; Maiello MR; Campiglio M; Napolitano M; Mancino M; Carotenuto A; Viglietto G; Menard S J Cell Physiol; 2006 May; 207(2):420-7. PubMed ID: 16419029 [TBL] [Abstract][Full Text] [Related]
8. Activated Src and Ras induce gefitinib resistance by activation of signaling pathways downstream of epidermal growth factor receptor in human gallbladder adenocarcinoma cells. Qin B; Ariyama H; Baba E; Tanaka R; Kusaba H; Harada M; Nakano S Cancer Chemother Pharmacol; 2006 Nov; 58(5):577-84. PubMed ID: 16532343 [TBL] [Abstract][Full Text] [Related]
9. Gefitinib reverses TRAIL resistance in human bladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression. Shrader M; Pino MS; Lashinger L; Bar-Eli M; Adam L; Dinney CP; McConkey DJ Cancer Res; 2007 Feb; 67(4):1430-5. PubMed ID: 17308080 [TBL] [Abstract][Full Text] [Related]
10. Dual-agent molecular targeting of the epidermal growth factor receptor (EGFR): combining anti-EGFR antibody with tyrosine kinase inhibitor. Huang S; Armstrong EA; Benavente S; Chinnaiyan P; Harari PM Cancer Res; 2004 Aug; 64(15):5355-62. PubMed ID: 15289342 [TBL] [Abstract][Full Text] [Related]
11. Metformin and erlotinib synergize to inhibit basal breast cancer. Lau YK; Du X; Rayannavar V; Hopkins B; Shaw J; Bessler E; Thomas T; Pires MM; Keniry M; Parsons RE; Cremers S; Szabolcs M; Maurer MA Oncotarget; 2014 Nov; 5(21):10503-17. PubMed ID: 25361177 [TBL] [Abstract][Full Text] [Related]
12. Combined targeting of epidermal growth factor receptor and MDM2 by gefitinib and antisense MDM2 cooperatively inhibit hormone-independent prostate cancer. Bianco R; Caputo R; Caputo R; Damiano V; De Placido S; Ficorella C; Agrawal S; Bianco AR; Ciardiello F; Tortora G Clin Cancer Res; 2004 Jul; 10(14):4858-64. PubMed ID: 15269162 [TBL] [Abstract][Full Text] [Related]
13. Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2. Chang CM; Chang PY; Tu MG; Lu CC; Kuo SC; Amagaya S; Lee CY; Jao HY; Chen MY; Yang JS Oncol Rep; 2012 Nov; 28(5):1799-807. PubMed ID: 22923287 [TBL] [Abstract][Full Text] [Related]
14. The PI3K/AKT pathway promotes gefitinib resistance in mutant KRAS lung adenocarcinoma by a deacetylase-dependent mechanism. Jeannot V; Busser B; Brambilla E; Wislez M; Robin B; Cadranel J; Coll JL; Hurbin A Int J Cancer; 2014 Jun; 134(11):2560-71. PubMed ID: 24374738 [TBL] [Abstract][Full Text] [Related]
15. EGFR tyrosine kinase inhibition radiosensitizes and induces apoptosis in malignant glioma and childhood ependymoma xenografts. Geoerger B; Gaspar N; Opolon P; Morizet J; Devanz P; Lecluse Y; Valent A; Lacroix L; Grill J; Vassal G Int J Cancer; 2008 Jul; 123(1):209-16. PubMed ID: 18386816 [TBL] [Abstract][Full Text] [Related]
16. Molecular aspects of gefitinib antiproliferative and pro-apoptotic effects in PTEN-positive and PTEN-negative prostate cancer cell lines. Festuccia C; Muzi P; Millimaggi D; Biordi L; Gravina GL; Speca S; Angelucci A; Dolo V; Vicentini C; Bologna M Endocr Relat Cancer; 2005 Dec; 12(4):983-98. PubMed ID: 16322337 [TBL] [Abstract][Full Text] [Related]
17. Blocking the PI3K/AKT and MEK/ERK signaling pathways can overcome gefitinib-resistance in non-small cell lung cancer cell lines. Li H; Schmid-Bindert G; Wang D; Zhao Y; Yang X; Su B; Zhou C Adv Med Sci; 2011; 56(2):275-84. PubMed ID: 22037177 [TBL] [Abstract][Full Text] [Related]
18. Marsdenia tenacissima extract restored gefitinib sensitivity in resistant non-small cell lung cancer cells. Han SY; Zhao MB; Zhuang GB; Li PP Lung Cancer; 2012 Jan; 75(1):30-7. PubMed ID: 21757251 [TBL] [Abstract][Full Text] [Related]
19. Combined inhibition of IGFR enhances the effects of gefitinib in H1650: a lung cancer cell line with EGFR mutation and primary resistance to EGFR-TK inhibitors. Choi YJ; Rho JK; Jeon BS; Choi SJ; Park SC; Lee SS; Kim HR; Kim CH; Lee JC Cancer Chemother Pharmacol; 2010 Jul; 66(2):381-8. PubMed ID: 19921194 [TBL] [Abstract][Full Text] [Related]
20. Gefitinib, a selective EGFR tyrosine kinase inhibitor, induces apoptosis through activation of Bax in human gallbladder adenocarcinoma cells. Ariyama H; Qin B; Baba E; Tanaka R; Mitsugi K; Harada M; Nakano S J Cell Biochem; 2006 Mar; 97(4):724-34. PubMed ID: 16229013 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]